HOME >> BIOLOGY >> NEWS
Rice researchers develop first fully automatic method to track 3-D movement of cancer cells

HOUSTON-- Sept. 16, 2002 -- Cancer researchers know the disease spreads from organ to organ in a non random pattern, but they are unable to predict exactly how cancer will spread, in part because of the limited tools available to study cancer cell migration in a controlled laboratory setting. In groundbreaking new research, Rice University scientists have designed a computerized system that can track the movement of individual cancer cells growing in a three-dimensional culture of model living tissue. The system can be used to categorize the metastatic patterns of different cancers and to help test the effectiveness of cancer-slowing or proposed cancer prevention drugs.

Described in the current issue of Cancer Research, the Rice study involved experiments on two types of cancer cells -- a strain of breast cancer and a variant of skin cancer. The researchers placed cancer cells from each strain into two types of simulated soft tissue. Using computer automation, the researchers tracked and analyzed the movement of individual cells as they migrated through the tissue.

The skin cancer migrated faster, spread further and penetrated deeper in both types of tissue. However, the research also revealed similarities between the strains. For example, both types of cells showed a tendency to oscillate, burrowing into tissue, reversing briefly and burrowing back along a slightly different vertical path. This suggests that both types of cancer invade tissue by seeking or creating a path of least resistance.

"The most important element of this work is not the differences we observed in the metastatic patterns of these two types of cancer, it's the methodology we developed to study the movement of cancer cells in living tissue," said study co-author Larry McIntire, chair of Rice's Institute of Biosciences and Bioengineering. "Studying tumor cell invasion in live cultures in real time is a significant advance."

Only with in vitro studies of 3-D cell m
'"/>

Contact: Jade Boyd
jadeboyd@rice.edu
713-348-6778
Rice University
16-Sep-2002


Page: 1 2

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2017)... , Aug. 15 2017   ivWatch LLC , a medical ... (IV) therapy, today announced receipt of its ISO 13485 Certification, the ... the International Organization for Standardization (ISO®). ... ivWatch Model 400 Continuous Monitoring device for the early detection ... "This is an important ...
(Date:6/14/2017)...  IBM (NYSE: IBM ) is introducing several innovative ... to developing collaboration between startups and global businesses, taking place ... the event, nine startups will showcase the solutions they have ... France is one ... a 30 percent increase in the number of startups created ...
(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... San Diego-based team building and cooking events company, ... today. The bold new look is part of a transformation to increase awareness, ... significant growth period. , It will also expand its service offering from its signature ...
(Date:10/10/2017)... Philadelphia, PA (PRWEB) , ... October 10, 2017 ... ... University City Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. ... accept the award for Excellence in Volunteer Experience from US2020. , US2020’s mission ...
(Date:10/10/2017)... , Oct. 10, 2017 International research firm Parks ... Strategy, will speak at the TMA 2017 Annual Meeting , October ... trends in the residential home security market and how smart safety and ... Parks ... "The residential ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... optimization firm for the life sciences and healthcare industries, announces a presentation by ... Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will present ...
Breaking Biology Technology:
Cached News: