HOME >> BIOLOGY >> NEWS
Rice researchers develop first fully automatic method to track 3-D movement of cancer cells

HOUSTON-- Sept. 16, 2002 -- Cancer researchers know the disease spreads from organ to organ in a non random pattern, but they are unable to predict exactly how cancer will spread, in part because of the limited tools available to study cancer cell migration in a controlled laboratory setting. In groundbreaking new research, Rice University scientists have designed a computerized system that can track the movement of individual cancer cells growing in a three-dimensional culture of model living tissue. The system can be used to categorize the metastatic patterns of different cancers and to help test the effectiveness of cancer-slowing or proposed cancer prevention drugs.

Described in the current issue of Cancer Research, the Rice study involved experiments on two types of cancer cells -- a strain of breast cancer and a variant of skin cancer. The researchers placed cancer cells from each strain into two types of simulated soft tissue. Using computer automation, the researchers tracked and analyzed the movement of individual cells as they migrated through the tissue.

The skin cancer migrated faster, spread further and penetrated deeper in both types of tissue. However, the research also revealed similarities between the strains. For example, both types of cells showed a tendency to oscillate, burrowing into tissue, reversing briefly and burrowing back along a slightly different vertical path. This suggests that both types of cancer invade tissue by seeking or creating a path of least resistance.

"The most important element of this work is not the differences we observed in the metastatic patterns of these two types of cancer, it's the methodology we developed to study the movement of cancer cells in living tissue," said study co-author Larry McIntire, chair of Rice's Institute of Biosciences and Bioengineering. "Studying tumor cell invasion in live cultures in real time is a significant advance."

Only with in vitro studies of 3-D cell m
'"/>

Contact: Jade Boyd
jadeboyd@rice.edu
713-348-6778
Rice University
16-Sep-2002


Page: 1 2

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... 2017 Today HYPR Corp. , leading ... component of the HYPR platform is officially FIDO® ... security architecture that empowers biometric authentication across Fortune 500 ... secured over 15 million users across the financial services ... home product suites and physical access represent a growing ...
(Date:3/30/2017)... , March 30, 2017 The research team ... for three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint ... new realm of speed and accuracy for use in identification, crime ... affordable cost. ... A ...
(Date:3/24/2017)... , March 24, 2017 The Controller General of ... Mr. Abdulla Algeen have received the prestigious international IAIR Award ... Continue Reading ... ... and Deputy Controller Abdulla Algeen (small picture on the right) have received ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... ... 2017 , ... Today, 3Bar Biologics Inc ., the ... funding from an impressive group of investors, including Rev1 Ventures, Maumee Ventures, Ohio ... investment, 3Bar is broadening availability of its groundbreaking offering that uses naturally occurring ...
(Date:8/15/2017)... After spending the past two years building a state-of-the-art ... GeneFo now offers this platform to healthcare stakeholders (hospitals, foundations, biopharma ... and data collection vis a vis their members, under their own ... of this offer. ... ...
(Date:8/15/2017)... ... 2017 , ... Any expert in stem cell research or stem cell medicine ... half a century. Despite their essential roles in human health and regenerative medicine, ... tags developed for this purpose also tag other, more abundant, non-stem tissue cells ( ...
(Date:8/15/2017)... ... August 15, 2017 , ... JULABO USA introduces ... the new website makes it easy to navigate through the site whether you’re ... find detailed product information, educational industry content and visit the company’s social media ...
Breaking Biology Technology:
Cached News: