HOME >> BIOLOGY >> NEWS
Rising expectations from new yeast study

Although studying the mating response of brewer's yeast may not stimulate most people, it's exciting stuff to University of Illinois at Chicago biologists David Stone and Metodi Metodiev. In the May 24 issue of the journal Science, they report an important finding about the way cells communicate in the yeast Saccharomyces cerevisiae. The finding may have implications for developing a range of pharmaceuticals, including new cancer treatments.

Saccharomyces cerevisiae has been widely studied and was the first eukaryote to have its genome fully sequenced. What makes this microbe a great research tool is that, although it is simpler than higher eukaryotes, its basic mechanisms of cellular function are the same as those of plant and animal cells, despite a billion years of divergent evolution.

Stone, an associate professor of biological sciences, and Metodiev, a research assistant professor, specialize in signal transduction the processes whereby cells consider the many thousands of stimuli they encounter and turn this information into the responses necessary for life. Stone began his study of yeast signal transduction in 1988.

The yeast exists as two mating types, like opposite sexes. Each mating type proliferates rapidly when grown in separate cultures, but when mixed, the opposite types communicate by secreting a chemical love potion called a pheromone. Exposure to pheromone causes the cells to stop dividing, then fuse, or mate.

"To us, the two most important aspects of the mating response are that first, pheromone triggers cells to stop dividing. Second, the cells are able to orient their growth toward the source of pheromone, a process called chemotropism," said Stone. "Growth control is of obvious importance because of its relationship to cancer. Chemotropism is of fundamental importance because we find many chemotropic phenomena in development in adult organisms. For example, our immune systems respond to chemical signals. When
'"/>

Contact: Paul Francuch
francuch@uic.edu
312-996-3457
University of Illinois at Chicago
23-May-2002


Page: 1 2 3

Related biology news :

1. Rising childhood leukaemia incidence prompts conference
2. Rising ozone levels pose challenge to U.S. soybean production, scientists say
3. Rising Maryland to welcome new biotech president
4. Rising rates of overweight among preschoolers in developing countries
5. Binocular rivalry: Fulfilling visual expectations
6. Purdue yeast makes ethanol from agricultural waste more effectively
7. Carnegie Mellon U biologists identify critical player in yeast ribosome assembly
8. Protein-only prions confirmed in FSU yeast study
9. Bakers yeast rises from genome duplication
10. Building a better atlas of yeast proteins
11. New findings in yeast may reveal why growing older is the greatest carcinogen in humans

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/26/2019)... ... February 26, 2019 , ... ... In her position as Account Manager, Ms. Baptiste demonstrated her ability to advocate ... experience. Ms. Baptiste was responsible for partnering with both the Strategic Development team ...
(Date:2/22/2019)... ... February 21, 2019 , ... Clean label food is ... when creating natural foods and beverages. It is quite common to spot consumers running ... meat products are not immune to this label scrutiny. , More than ever, ...
(Date:2/22/2019)... ... February 21, 2019 , ... The ... executed a research agreement establishing a collaborative program to work toward applications of ... develop new radiopharmaceutical lead candidates and will explore Fuzionaire Dx’s platform as a ...
Breaking Biology News(10 mins):
(Date:3/14/2019)... ... 14, 2019 , ... Open registration for the Case Management ... of Case Management,” continues as CMSA makes plans to host the annual event ... management industry conference serving the educational and networking needs of case and care ...
(Date:3/14/2019)... (PRWEB) , ... March 13, 2019 , ... ... its 2019 ISPE Europe Biotechnology Conference , taking place in Brussels, Belgium ... biotechnology best practices, technical and operational solutions, and innovative approaches. , “Biopharmaceuticals ...
(Date:3/12/2019)... (PRWEB) , ... March 12, 2019 , ... ... preparation and epigenetics research, has launched its third generation long-fragment DNA shearing innovation, ... generation instrument with a user-friendly interface, automated processing, and the ability to ...
(Date:3/9/2019)... ... March 07, 2019 , ... ACEA Biosciences ... development and commercialization of high performance, cutting-edge cell analysis platforms for life science ... GLP-certified expertise in cardiovascular pharmacology and electrophysiology, are announcing a partnership to provide ...
Breaking Biology Technology:
Cached News: