HOME >> BIOLOGY >> NEWS
Roderick MacKinnon wins 2003 Nobel Prize in Chemistry

Roderick MacKinnon, a Howard Hughes Medical Institute (HHMI) investigator at The Rockefeller University, is one of two scientists who were awarded the 2003 Nobel Prize in Chemistry for discoveries concerning channels in cell membranes.

MacKinnon shared the prize with Peter Agre of the Johns Hopkins University. Agre is currently a member of HHMI's scientific review board. The two scientists were honored for discoveries clarifying "how salts (ions) and water are transported out of and into the cells of the body," according to the Royal Swedish Academy of Sciences.

"This is appropriate recognition for the beauty of MacKinnon's science and the clarity with which he expresses the biological phenomenon," said HHMI President Thomas R. Cech, who won the Nobel Prize in Chemistry in 1989. "MacKinnon's work is exquisite, but he also makes the data come alive with very thoughtful and clear explanations."

In 1998, much to the surprise of colleagues, MacKinnon and his colleagues determined the three-dimensional structure of a pore that allows cells to control their intake of potassium ions. By determining the structure of the potassium pore, or channel, MacKinnon and his colleagues at The Rockefeller University had solved a riddle that has perplexed biophysicists for decades: How does a potassium channel admit millions of potassium ions per second, while allowing only one smaller sodium ion to slip through for every 1,000 potassium ions?

The answer is important because potassium channels are part of the apparatus that maintains the normal ionic balance across the cell membrane. In excitable cells, like those in nerves and muscles, for example, the channels help re-establish the electrical difference between the inside and outside of the cells after excitation. Without potassium and sodium channels, neurons could not generate electrical signals and hearts could not beat rhythmical
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
8-Oct-2003


Page: 1 2 3 4

Related biology news :

1. MacKinnon labs newest picture tells action potential story
2. Press workshop Life, a Nobel Story
3. Structure of a Nobel-prize winning molecule: Aquaporin
4. Marie Curie Nobel Centennial Celebration of Women in Science
5. Illinois professor wins Nobel Prize
6. UT Southwestern Nobelists find protein structure that may help fight high cholesterol
7. Kurt Wthrich of The Scripps Research Institute wins 2002 Nobel Prize in Chemistry
8. Sydney Brenner, Molecular Sciences Institute founder, awarded the Nobel Prize
9. Salk Institute professor Sydney Brenner receives 2002 Nobel Prize for medicine
10. NLM exhibit features Nobelist Joshua Lederberg
11. Günter Blobel wins 1999 Nobel Prize for physiology or medicine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/5/2018)... ... October 04, 2018 , ... ... of Illinois Extension and Monroe County Economic Development Corporation (EDC), has been ... of Food and Agriculture (NIFA) Non-Land Grant College of Agriculture (NLGCA) Capacity-Building ...
(Date:10/3/2018)... ... October 03, 2018 , ... Fit4D, a leading ... of healthcare visionary, Jimmy Lee, as Strategic Advisor to the company’s board. Mr. ... industry experience. As a Senior Executive at Anthem, he had P&L accountability for ...
(Date:10/2/2018)... ... 02, 2018 , ... Through this webinar, sponsored by Molecular Devices , ... learn the role of calcium kinetics in cardiac safety testing. The speakers for this ... Biography; and Tsang Wai Lam, an assay development scientist at PPSC. , They will ...
Breaking Biology News(10 mins):
(Date:10/18/2018)... (PRWEB) , ... October 18, 2018 , ... With rapid ... freeze and store their eggs. Previously reserved for women facing a cancer diagnosis requiring ... doing so to preserve their options. Simply put, they do not want to ...
(Date:10/16/2018)... (PRWEB) , ... October 16, 2018 , ... ... Dr. Isabel Moreno-Indias, PhD, Senior Researcher at the Biomedical Research Institute of ... the Physiopathology Network of Obesity and Nutrition, to its Scientific Advisory Board. Joining ...
(Date:10/13/2018)... ... October 12, 2018 , ... The ... education, innovation and commercialization, celebrates its 50th birthday in New York’s Times Square ... and Electro-Optics (ICALEO) conference. , In celebration of its 50 years, LIA ...
(Date:10/5/2018)... WILMINGTON, N.C. (PRWEB) , ... October 04, 2018 ... ... announced today that it has received a Spine Technology Award from Orthopedics This ... Angeles, CA last week. The Power T Handle is a surgical instrument that ...
Breaking Biology Technology:
Cached News: