HOME >> BIOLOGY >> NEWS
Rutgers scientists discover protein in brain affects learning and memory

NEW BRUNSWICK/PISCATAWAY, N.J. Rutgers researchers have discovered what could be the newest target for drugs in the treatment of memory and learning disabilities as well as diseases such as Alzheimer's and fetal alcohol syndrome: a protein known as cypin.

Cypin is found throughout the body, but in the brain it regulates nerve cell or neuron branching. Branching or dendrite growth is an important process in normal brain function and is thought to increase when a person learns. A reduction in branching is associated with certain neurological diseases.

"The identification of cypin and understanding how it works in the brain is particularly exciting since it opens up new avenues for the treatment of serious neurological disorders," said principal investigator Bonnie Firestein, assistant professor of cell biology and neuroscience at Rutgers, The State University of New Jersey. "This paves the way to designing new drugs that could target this protein molecule."

Proteins or the genes that code for them have become the targets of choice for developing precisely focused, effective new drug therapies one of the outcomes of the many revelations provided by the Human Genome Project.

Firestein first identified and isolated cypin in 1999 during her postdoctoral research. She is currently focusing on how it works in the hippocampus, a structure in the brain associated with the regulation of emotions and memory.

"We knew that cypin existed elsewhere in the body where it performs other functions, but no one knew why it was present in the brain," Firestein. Her new research determined that cypin in the brain works as an enzyme involved in shaping neurons.

"One end of a neuron looks like a tree and, in the hippocampus, cypin controls the growth of its branches," she explained. "An increase in the number of branches provides additional sites where a neuron can receive information that it can pass along, enhancing communication
'"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x652
Rutgers, the State University of New Jersey
18-Jan-2004


Page: 1 2

Related biology news :

1. Rutgers-Newark biologist links presence of protein to spread of cancerous cells
2. Rutgers-Newark scientist: Mosquitoes may carry lethal parasite
3. Rutgers cancer prevention expert calls for FDA action to reduce colon cancer and osteoporosis
4. Rutgers chemist uses NMR to elucidate protein-DNA interaction
5. Ocean dye to help Rutgers scientists trace Hudson Rivers path miles into the Atlantic
6. Rutgers ecologists and Brooklyn Botanic Garden botanists to plan Beijing Olympics Forest Park
7. Radioactive and toxic waste site plans are a recipe for disaster, says Rutgers sociologist
8. Rutgers researcher offers a new perspective on human evolution
9. President Bush names Rutgers Evelyn Witkin for nations highest science honor
10. Rutgers geneticist to battle autism with $3.7 million NIH grant
11. Grant of powerful computer to Rutgers-Newark will increase understanding of brain activity

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2019)... ... April 02, 2019 , ... Orbsen ... stromal cell immunotherapies, announced it will move its base of operations from the ... the University’s newly created biotechnology park in Galway, Ireland. , “With four clinical ...
(Date:4/4/2019)... VIEJO, Calif. (PRWEB) , ... April 02, 2019 ... ... leading clinical genetics testing company, will present results demonstrating that RNA genetic testing ... cancer genetic testing. This study, awarded as a Top Rated poster, is one ...
(Date:4/1/2019)... ... April 01, 2019 , ... uBiome announces the ... Conditions” by the US Patent and Trademark Office on January 1, 2019 with ... uBiome collaborators Dr. Zachary Apte, Dr. Daniel Almonacid, Dr. Jessica Richman, and ...
Breaking Biology News(10 mins):
(Date:4/8/2019)... ... April 08, 2019 , ... CallTower, a ... the launch of their app integration solution, CT Cloud Unite. CT Cloud ... while using CT Cloud Voice and Skype for Business solutions. This robust integration ...
(Date:4/4/2019)... ... April 02, 2019 , ... ... would be releasing it’s latest field-ready solution for performing PCR, RT-PCR, qPCR, and ... Franklin™ pays homage to Rosland Franklin, an English chemist and X-ray crystallographer who ...
(Date:3/27/2019)... ... , ... A leader in the field of Regenerative Veterinary Medicine, VetStem Biopharma ... and Canada since 2004. The primary indications for VetStem Regenerative Cell Therapy are ... cat, and horse. Recently, VetStem teamed up with the world-renowned San Diego Zoo ...
(Date:3/23/2019)... ... March 22, 2019 , ... uBiome has awarded ... team of researchers at Nnamdi Azikiwe University in Anambra State, Nigeria led by ... of the Department of Medical Laboratory Sciences and Deputy Provost, College of Health ...
Breaking Biology Technology:
Cached News: