HOME >> BIOLOGY >> NEWS
SARS information for antiviral drug design released by Protein Data Bank

NEW BRUNSWICK/PISCATAWAY, N.J. -- The Protein Data Bank (PDB), an international resource for biomedical research with facilities at Rutgers, The State University of New Jersey, has released to the public a three-dimensional crystal structure of the SARS virus main protease enzyme. Its availability to medical researchers worldwide is crucial because this enzyme is considered the primary target for new antiviral drugs being developed to combat the virus.

"The PDB was able to process and release this information so quickly because of the leading-edge technology it employs," said Rutgers Board of Governors Professor of Chemistry and Chemical Biology Helen M. Berman, director of the Protein Data Bank. "It is critically important that these kinds of data are made available quickly to expedite the drug discovery process, especially when we are dealing with a potentially epidemic disease like SARS. The rapid processing possible by the PDB is going to become increasingly important as we release structures with such medically important potential."

The actual structure determination was made by Structural GenomiX, Inc., a biotechnology company in San Diego. The company deposited its data with the PDB, which were processed rapidly by a team at Rutgers to make the data available in the public database.

"Having the three-dimensional structure of the SARS virus protease should accelerate the search for effective treatments for SARS," said Eddy Arnold, professor, Rutgers' department of chemistry and chemical biology. "Structure-based drug design has had an important impact on the development of anti-AIDS drugs that are now in use, and the rapid progress with characterizing the SARS coronavirus will enable more efficient paths to developing drugs for treating SARS. The PDB renders an important service to the research community in providing rapid access to this crucial information."

The Protein Data Bank is an Internet-accessible internation
'"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x616
Rutgers, the State University of New Jersey
30-Jul-2003


Page: 1 2

Related biology news :

1. Spanish scientists develop powerful tool for exploration and integration of biological information
2. Many scientists believe the dog genome holds information that will benefit human health
3. Research on inherited eye disorders uncovers new information about blood-vessel formation
4. Statistical technique helps researchers gain more information from a single data run
5. CIESIN receives grant to establish government biological information site
6. Workshop takes systems view of information processing in organisms
7. Landmark study offers new information about breast cancer genes
8. Saliva spits out information on chemical exposure
9. Carnegie Mellon receives $2.5M to develop bio-molecular imaging and information discovery systems
10. Data privacy, emergency response, weather prediction to benefit from information technology advances
11. UC San Diego researchers receive $14 million from NSF for 10 new information technology projects

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2017)... Calif. , April 18, 2017  Socionext Inc., a global ... of a media edge server, the M820, which features the company,s ... recognition software provided by Tera Probe, Inc., will be showcased during ... at the NAB show at the Las Vegas ... ...
(Date:4/13/2017)... , April 13, 2017 According to a ... Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, Deployment ... the IAM Market is expected to grow from USD 14.30 Billion in ... Rate (CAGR) of 17.3%. ... MarketsandMarkets Logo ...
(Date:4/11/2017)... 11, 2017 No two people are ... the New York University Tandon School of Engineering ... found that partial similarities between prints are common ... mobile phones and other electronic devices can be ... vulnerability lies in the fact that fingerprint-based authentication ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting in North Carolina, ... Harvard University’s Departments of Physics and Astronomy, has been selected for membership in ... team for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... providing advanced instruments and applications consulting for microscopy and surface analysis, Nanoscience ... application consulting, Nanoscience Analytical offers a broad range of contract analysis services ...
(Date:10/6/2017)... ... October 06, 2017 , ... ... healthcare and technology sector at their fourth annual Conference where founders, investors, innovative ... speakers and the ELEVATE pitch competition showcasing early stage digital health and med ...
(Date:10/5/2017)... PA (PRWEB) , ... October 05, 2017 , ... Understanding ... the newest frontiers in human health. Gut Love: You Are My Future, the newest ... an artist’s perspective as it explores the human condition through the lens of the ...
Breaking Biology Technology:
Cached News: