HOME >> BIOLOGY >> NEWS
SARS information for antiviral drug design released by Protein Data Bank

NEW BRUNSWICK/PISCATAWAY, N.J. -- The Protein Data Bank (PDB), an international resource for biomedical research with facilities at Rutgers, The State University of New Jersey, has released to the public a three-dimensional crystal structure of the SARS virus main protease enzyme. Its availability to medical researchers worldwide is crucial because this enzyme is considered the primary target for new antiviral drugs being developed to combat the virus.

"The PDB was able to process and release this information so quickly because of the leading-edge technology it employs," said Rutgers Board of Governors Professor of Chemistry and Chemical Biology Helen M. Berman, director of the Protein Data Bank. "It is critically important that these kinds of data are made available quickly to expedite the drug discovery process, especially when we are dealing with a potentially epidemic disease like SARS. The rapid processing possible by the PDB is going to become increasingly important as we release structures with such medically important potential."

The actual structure determination was made by Structural GenomiX, Inc., a biotechnology company in San Diego. The company deposited its data with the PDB, which were processed rapidly by a team at Rutgers to make the data available in the public database.

"Having the three-dimensional structure of the SARS virus protease should accelerate the search for effective treatments for SARS," said Eddy Arnold, professor, Rutgers' department of chemistry and chemical biology. "Structure-based drug design has had an important impact on the development of anti-AIDS drugs that are now in use, and the rapid progress with characterizing the SARS coronavirus will enable more efficient paths to developing drugs for treating SARS. The PDB renders an important service to the research community in providing rapid access to this crucial information."

The Protein Data Bank is an Internet-accessible internation
'"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x616
Rutgers, the State University of New Jersey
30-Jul-2003


Page: 1 2

Related biology news :

1. Spanish scientists develop powerful tool for exploration and integration of biological information
2. Many scientists believe the dog genome holds information that will benefit human health
3. Research on inherited eye disorders uncovers new information about blood-vessel formation
4. Statistical technique helps researchers gain more information from a single data run
5. CIESIN receives grant to establish government biological information site
6. Workshop takes systems view of information processing in organisms
7. Landmark study offers new information about breast cancer genes
8. Saliva spits out information on chemical exposure
9. Carnegie Mellon receives $2.5M to develop bio-molecular imaging and information discovery systems
10. Data privacy, emergency response, weather prediction to benefit from information technology advances
11. UC San Diego researchers receive $14 million from NSF for 10 new information technology projects

Post Your Comments:
(Date:5/21/2015)... May 21, 2015 According ... Market by Solutions (Hardware, Software, Services), by Applications (Surveillance ... others), by End-Users (Military & Defense & Commercial) ... Thermal Imaging Market is expected to grow from ... 2020, at a Compound Annual Growth Rate (CAGR) ...
(Date:5/19/2015)... Fingerprint Cards (FPC) has received an order for ... from one if its module partners. Deliveries are planned to ... the sensors will be used by smartphone manufacturers in ... amount to 740 MSEK to date. In addition to previously ... number of smaller orders not separately communicated amounting to more ...
(Date:5/14/2015)... DUBLIN , May 14, 2015 Research and ... addition of the "Fingerprint Sensors Market in Smart ... This report believes that 2014 was a watershed ... to Apple,s introduction of ,Apple Pay,. Apple gave fingerprint ... its mobile payment service. Fingerprint sensors are a must-have ...
Breaking Biology News(10 mins):Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Global Smart Mobile Devices Fingerprint Sensors Market 2015-2019: Key Vendors are Authentec, Validity Sensors, Fingerprint Cards, Next Biometrics Group. IDEX, and Qualcomm 2
(Date:5/28/2015)... , May 28, 2015 RXi Pharmaceuticals Corporation ... discovering and developing innovative therapeutics, primarily in the areas ... a public offering of 26 million units at a ... gross proceeds of approximately $10.4 million. Each unit consists ... 13-month overallotment purchase right to purchase 0.50 of a ...
(Date:5/28/2015)... 28, 2015  GenVec, Inc. (Nasdaq: GNVC ) ... J. Swirsky , will present a company overview at ... EDT on Thursday, June 4, 2015. ... will be available at the following link:  http://wsw.com/webcast/jeff88/gnvc ... website.  To access, visit www.genvec.com , click on ...
(Date:5/28/2015)... (PRWEB) May 28, 2015 The Fertility ... our own Dr. Danielle Vitiello has taken on a ... role, Dr. Vitiello will provide guidance, leadership, oversight and ... to count Dr. Vitiello among our team of experienced ... and CEO, Joseph A. Hill, M.D. “Her expertise and ...
(Date:5/28/2015)... 28, 2015 Whitehouse Laboratories is excited ... long term partnership with PTI Inspection Systems. Whitehouse Labs ... clients with custom-tailored method development and validation programs ... available. The agreement includes a more formal program that ... organizational lines. This enables a more effective team approach, ...
Breaking Biology Technology:RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 3GenVec To Present At The Jefferies Healthcare Conference 2Danielle Vitiello, MD of Fertility Centers of New England, Named New Medical Director 2Whitehouse Labs Renews & Enhances Partnership with PTI Inspection Systems 2Whitehouse Labs Renews & Enhances Partnership with PTI Inspection Systems 3
Cached News: