HOME >> BIOLOGY >> NEWS
SARS information for antiviral drug design released by Protein Data Bank

NEW BRUNSWICK/PISCATAWAY, N.J. -- The Protein Data Bank (PDB), an international resource for biomedical research with facilities at Rutgers, The State University of New Jersey, has released to the public a three-dimensional crystal structure of the SARS virus main protease enzyme. Its availability to medical researchers worldwide is crucial because this enzyme is considered the primary target for new antiviral drugs being developed to combat the virus.

"The PDB was able to process and release this information so quickly because of the leading-edge technology it employs," said Rutgers Board of Governors Professor of Chemistry and Chemical Biology Helen M. Berman, director of the Protein Data Bank. "It is critically important that these kinds of data are made available quickly to expedite the drug discovery process, especially when we are dealing with a potentially epidemic disease like SARS. The rapid processing possible by the PDB is going to become increasingly important as we release structures with such medically important potential."

The actual structure determination was made by Structural GenomiX, Inc., a biotechnology company in San Diego. The company deposited its data with the PDB, which were processed rapidly by a team at Rutgers to make the data available in the public database.

"Having the three-dimensional structure of the SARS virus protease should accelerate the search for effective treatments for SARS," said Eddy Arnold, professor, Rutgers' department of chemistry and chemical biology. "Structure-based drug design has had an important impact on the development of anti-AIDS drugs that are now in use, and the rapid progress with characterizing the SARS coronavirus will enable more efficient paths to developing drugs for treating SARS. The PDB renders an important service to the research community in providing rapid access to this crucial information."

The Protein Data Bank is an Internet-accessible internation
'"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x616
Rutgers, the State University of New Jersey
30-Jul-2003


Page: 1 2

Related biology news :

1. Spanish scientists develop powerful tool for exploration and integration of biological information
2. Many scientists believe the dog genome holds information that will benefit human health
3. Research on inherited eye disorders uncovers new information about blood-vessel formation
4. Statistical technique helps researchers gain more information from a single data run
5. CIESIN receives grant to establish government biological information site
6. Workshop takes systems view of information processing in organisms
7. Landmark study offers new information about breast cancer genes
8. Saliva spits out information on chemical exposure
9. Carnegie Mellon receives $2.5M to develop bio-molecular imaging and information discovery systems
10. Data privacy, emergency response, weather prediction to benefit from information technology advances
11. UC San Diego researchers receive $14 million from NSF for 10 new information technology projects

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/19/2016)... UAE, April 20, 2016 The ... as a compact web-based "all-in-one" system solution for all ... fingerprint reader or the door interface with integration authorization ... access control systems. The minimal dimensions of the access ... into the building installations offer considerable freedom of design ...
(Date:4/14/2016)... April 14, 2016 BioCatch ... Detection, today announced the appointment of Eyal Goldwerger ... role. Goldwerger,s leadership appointment comes at a ... of the deployment of its platform at several of ... technology, which discerns unique cognitive and physiological factors, is ...
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... -- Global demand for enzymes is forecast to grow ... billion.  This market includes enzymes used in industrial ... animal feed, and other markets) and specialty applications ... beverages will remain the largest market for enzymes, ... containing enzymes in developing regions.  These and other ...
(Date:6/27/2016)... 2016  Sequenom, Inc. (NASDAQ: SQNM ), ... through the development of innovative products and services, announced ... United States denied its petition to review ... Sequenom,s U.S. Patent No. 6,258,540 (",540 Patent") are not ... the Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories ...
(Date:6/27/2016)... CA (PRWEB) , ... June 27, 2016 , ... ... for clinical trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT ... care circle with the physician and clinical trial team. , Using the CONSULT module, ...
(Date:6/27/2016)... ... June 27, 2016 , ... Rolf ... join the faculty of the University of North Carolina Kenan-Flagler Business School ... and entrepreneurship at UNC Kenan-Flagler, with a focus on the school’s international efforts, ...
Breaking Biology Technology:
Cached News: