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SARS virus can change quickly and unpredictably, analysis indicates

from parts of RDRP genes taken from different coronavirus lineages sometime in the past.

"Our results do not mean that human infection by SARS-CoV is linked to the particular recombination event for which we found evidence," said Mindell. "But demonstration of recombination in the SARS-CoV lineages does indicate its potential for rapid, unpredictable evolutionary change, and this is a potentially important challenge for public health management and for drug and vaccine development."


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Contact: Nancy Ross Flanigan
rossflan@umich.edu
734-647-1853
University of Michigan
2-Oct-2003


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