HOME >> BIOLOGY >> NEWS
Sandia Discovery About Protein May Help Clean Up Pollutants, Find Cures For Diseases

ALBUQUERQUE, N.M -- A discovery linking the shape of a unit called the heme in a protein to protein function may prove useful in a range of scientific advances, including finding cures for diseases and cleaning up pollutants, says discoverer John Shelnutt, a physicist at the Department of Energy's Sandia National Laboratories. The first time such a correlation has been made, the discovery is being heralded by the biochemical and biophysical communities as one of the most intriguing new findings about proteins in recent years.

Proteins -- strings of amino acids -- are found in all living cells and are where the work of a cell occurs. The heme, which consists of a ring of carbons and nitrogens, is the portion of a "hemoprotein" that clasps the protein's iron atom in place. A single protein may contain as few as one heme or as many as ten.

"Before, people always thought the heme's primary function was to simply hold the iron in the protein so that the iron could carry out some biochemical reaction," Shelnutt says. "They weren't aware that the heme acted as part of the protein 'machine' and changed shape or even had shape. Many even believed it was flat [which it is outside the protein]. We've shown that that inside the protein the heme is three-dimensional, or nonplanar, and its shape corresponds to function."

Further, he's demonstrated that in many instances the heme's shape changes as it performs its job. "The main thing my discovery has done is provide a new way to look at hemeproteins and what they do," he says. "We're revealing previously hidden influences of the protein on the heme structure." Shelnutt says that initially his findings were so startling that when he first tried to publish his results "no one believed me or would publish them."

His observations finally appeared in a 1998 issue of Biophysical Journal. Since then, his research has captured the interest of the biochemical and biophysical communities. At a March meeting of the A
'"/>

Contact: Chris Burroughs
coburro@sandia.gov
505-844-0948
DOE/Sandia National Laboratories
26-Apr-1999


Page: 1 2 3

Related biology news :

1. Sandia experiments may reduce possibility of future water wars
2. $6 million appropriation to focus Sandia research on drinking water desalination, removal of arsenic
3. Sandia-aided method to heal wounded and diseased achieves US government acceptance
4. Sandia pursues biotechnology as new technology focus area
5. Sandia-developed formulation among products selected to help rid U.S. facilities of anthrax
6. Sandia portable chemical sensor system promises new way of detecting underwater explosives
7. Sandia-developed remote sensor expected to analyze gases up to two miles away
8. Sandia, University Of Montana Researchers Try Training Bees To Find Buried Landmines
9. Sandia Decontamination Foam May Be Tomorrows Best First Response In A Chem-Bio Attack
10. Improved Oxygen Bath To Heal Wounds, Lessen Number Of Amputations: Sandia To Sign Agreement With Numotech To Help Create Home-Use Healing Facility
11. Tracking Hepatitis C: Health Project Demos Worldwide Early-Warning System For Disease Outbreaks; Sandia Tests Disease-Tracking Approach

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2017)... , March 21, 2017 Vigilant Solutions ... serving law enforcement agencies, announced today the appointment of ... director of public safety business development. Mr. ... enforcement experience, including a focus on the aviation transportation ... most recent position, Mr. Sheridan served as the Aviation ...
(Date:3/16/2017)... HANOVER, Germany , March 16, 2017 CeBIT 2017 - Against ... Continue Reading ... Used combined in one project, multi-biometric solutions ... ... Identification Systems) ...
(Date:3/9/2017)... and MOUNTAIN VIEW, Calif. , ... Well Made Simple," and 23andMe , the leading ... better food choices.  Zipongo can now provide customers with ... preferences, health goals and biometrics, but also genetic markers ... choices. Zipongo,s personalized food decision support platform ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... Va. , March 27, 2017  Perthera,s Chief ... Cancer Center, Subha Madhavan , Ph.D., will be ... Joint Summits Panels. On Monday, March 27, 2017, she ... Oncology Data More Usable for Research and Care" (from ... March 28, 2017, she will be a participant in ...
(Date:3/27/2017)... , March 27, 2017 DarioHealth Corp. ... mobile health and big data solutions, today announced that ... insurance coverage option for U.S. consumers who want to ... DarioHealth has signed strategic alliance agreements with partners ... insurance coverage benefits, and if approved, will supply and ...
(Date:3/24/2017)... 24, 2017 Sinovac Biotech Ltd. ("Sinovac" or the "Company") ... China , today announced that its board of directors has ... the plan from March 27, 2017 to March 27, 2018. The amendment ... About Sinovac Biotech Ltd. ... Sinovac Biotech Ltd. is a China ...
(Date:3/23/2017)... ... 2017 , ... Lajollacooks4u is proud to announce it has become the premiere team-building cooking event ... companies around the world, such as Illumina, HP and Qualcomm, and is ranked #1 in ... popularity is due to its new team building format, a way for teams to not ...
Breaking Biology Technology:
Cached News: