HOME >> BIOLOGY >> NEWS
Sandia Discovery About Protein May Help Clean Up Pollutants, Find Cures For Diseases

emes were conserved, that is, the same shape is found in multiple proteins from different species."

Another new concept that Shelnutt's research has revealed is that many hemes change shape and go from one distortion to another as they perform their work. For example, when a certain protein binds with oxygen, the heme in the protein changes shape, loosing its ruffling distortion. This causes the protein itself to change shape, turning off a biochemical reaction called nitrogen fixation. Then, when oxygen is no longer around, the heme ruffles once again, and nitrogen fixation is switched back on.

"Sometimes, though, the heme doesn't change at all," Shelnutt says. "It just depends on the job that needs to be done."

Shelnutt's interest in protein analysis and hemes dates back about ten years when he was researching the prospect of engineering molecules to, for example, change gaseous fuel to liquid fuel. Having a history of working with heme proteins at Bell Labs, he wondered if a protein could alter the heme's shape and function as well.

Shelnutt believes that his discovery might lead to changes in the way diseases are treated in the future or for other scientific advances. In collaboration with a French scientist, he is already using his knowledge to develop new anti-inflammatory drugs.

Another possibility is to understand how hemes from another protein Shelnutt is working with convert sulfites or nitrites -- common pollutants -- into hydrogen sulfide or ammonia. Then, analogous arrangements of hemes could be chemically engineered, produced in batches, and released to clean up waste sites.

"The revelation that heme shape is correlated to a protein's function is so new that we don't yet know where this knowledge can take us," Shelnutt says. "We have a new key to better understand life and now we have to figure out what to do with it."


'"/>

Contact: Chris Burroughs
coburro@sandia.gov
505-844-0948
DOE/Sandia National Laboratories
26-Apr-1999


Page: 1 2 3

Related biology news :

1. Sandia experiments may reduce possibility of future water wars
2. $6 million appropriation to focus Sandia research on drinking water desalination, removal of arsenic
3. Sandia-aided method to heal wounded and diseased achieves US government acceptance
4. Sandia pursues biotechnology as new technology focus area
5. Sandia-developed formulation among products selected to help rid U.S. facilities of anthrax
6. Sandia portable chemical sensor system promises new way of detecting underwater explosives
7. Sandia-developed remote sensor expected to analyze gases up to two miles away
8. Sandia, University Of Montana Researchers Try Training Bees To Find Buried Landmines
9. Sandia Decontamination Foam May Be Tomorrows Best First Response In A Chem-Bio Attack
10. Improved Oxygen Bath To Heal Wounds, Lessen Number Of Amputations: Sandia To Sign Agreement With Numotech To Help Create Home-Use Healing Facility
11. Tracking Hepatitis C: Health Project Demos Worldwide Early-Warning System For Disease Outbreaks; Sandia Tests Disease-Tracking Approach

Post Your Comments:
(Date:4/17/2014)... State University engineer has developed a patented technique ... explosive devices. The same technique could help police ... M. and Kay L. Theede chair in engineering ... and his research team have created a template-based ... car trunks. The distance detection method called ...
(Date:4/17/2014)... Several parasites and pathogens that devastate honeybees in Europe, ... Africa, but do not appear to be impacting native ... team of researchers., The invasive pests include including ... East African honeybees appear to be resilient to these ... used to control pests in Europe, Asia and the ...
(Date:4/17/2014)... Cell Press journal Current Biology on April ... sex lives. The Brazilian insects, which represent four distinct ... are the first example of an animal with sex-reversed ... in several different animals, Neotrogla is the ... reversed," says Kazunori Yoshizawa from Hokkaido University in Japan. ...
Breaking Biology News(10 mins):Patented research remotely detects nitrogen-rich explosives 2East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3In sex-reversed cave insects, females have the penises 2
(Date:1/14/2014)... January 14, 2014 Date: Friday, April 11, ... Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... organization solely dedicated to finding a cure for hepatitis B ... will host its annual Crystal Ball on Friday, April 11 ...
(Date:1/14/2014)... 14, 2014 EquitiesIQ, a leading informational ... ALQA). Alliqua is an emerging biomedical company acquiring, developing, ... care market. , Free report download: http://equitiesiq.com/reports/alliqua/ ... seasoned management team and Board, which launched the company’s ...
(Date:1/14/2014)... Jan. 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: RXII), ... commercializing innovative therapies addressing major unmet medical needs ... the Notice of Allowance from the United States ... RNAi compounds (sd-rxRNA®), for the treatment of fibrosis. ...
(Date:1/14/2014)... During the 1600’s through the 1800’s doctors contributed ... In this time period, doctors did not know that they ... the death of vulnerable patients. In the same way, medical ... be unwittingly transmitting herpes viruses to their patients. The CBCD ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
Cached News: