HOME >> BIOLOGY >> NEWS
Scientist finds genetic clues to Alzheimer's, establishes DNA bank for future studies

Tiny flaws have been found on three chromosomes in patients with the most common type of Alzheimer's disease by a researcher at the Medical College of Georgia.

These flaws pave the way for discovery of the genes responsible for late-onset Alzheimer's, in which symptoms begin after age 65, and lead to better ways to diagnose and treat the devastating disease, said Dr. Shirley E. Poduslo, neuroscientist.

Dr. Poduslo found the flaws studying DNA donated by Texas families affected by late-onset Alzheimer's while she was director of basic research for the Department of Neurology at Texas Tech University Health Sciences Center in Lubbock. Her research is published in the December issue of the British journal NeuroReport.

Now Dr. Poduslo, who joined the MCG faculty in November, has established a similar DNA bank for patients and their families from throughout Georgia and South Carolina to enable future studies.

"If you live to be 65, you have a 5 percent chance of developing Alzheimer's disease," Dr. Poduslo said. "If you live to be 85, you have a 50 percent chance. If you have a family history, there is an increased risk, no doubt about it," she said of the disease that affects about 4 million Americans today with a health care tab of $80 billion. "As our baby boomers age and retire, we are going to have a national crisis on our hands."

In Texas she enrolled nearly 500 patients, including 15 large, extended families, in her state-funded DNA bank. She was overwhelmed by the response of Texans. "It's something the families can do and it's something that is not difficult for them to do," Dr. Poduslo said of the process of collecting family histories, patients' medical records and blood. She's hoping for a similar response from Georgians and South Carolinians so that work to uncover the genetics of late-onset disease - which accounts for about 95 percent of Alzheimer's - can continue.

"We have really good evidence now that even late-onset
'"/>

Contact: Toni Baker
tbaker@mail.mcg.edu
706-721-4421
Medical College of Georgia
7-Jan-2002


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... August 14, 2019 , ... Gateway Genomics , a leading ... inclusion in the 38th annual Inc. 500|5000 list of fastest growing private ... companies must have been founded and generating revenue by March 31, 2015. Ranking in ...
(Date:8/14/2019)... ... ... Julie Reck of Veterinary Medical Center of Fort Mill has recently begun providing ... her own geriatric Australian Shepherd, Simon, was treated in June 2019 for osteoarthritis in his ... body was weak, and he struggled to play fetch and other games with his family. ...
(Date:8/6/2019)... ... August 06, 2019 , ... A study released today in ... far-reaching implications for personalized medicine, especially when seeking treatments for children with heart ... which stem cell donors and manipulation methods might yield the best therapies for ...
Breaking Biology News(10 mins):
(Date:9/11/2019)... ... 2019 , ... An upcoming episode of Advancements with Ted ... sequencing analysis. Check your local listings for more information. , Advancements will go ... and will explore its revolutionary pathogenic DNA analysis technology, which predicts in real-time, ...
(Date:9/8/2019)... , ... September 05, 2019 , ... ... Blaine Fitzgerald, former Vice President of Finance for Shopify, has been named Chief ... and healthcare venture capitalist Joel Finlayson as strategic advisors. Additionally, Spartan has hired ...
(Date:8/29/2019)... ... August 28, 2019 , ... ... Danisco® ingredient solutions to attendees at the International Baking Industry Expo, September 8 ... challenges from optimizing production efficiency to cost and waste reduction and from maintaining ...
(Date:8/25/2019)... ... 2019 , ... Authors Gopal Nayak and Mahendra Kumar Trivedi ... “Impact of Biofield Treatment on Growth and Anatomical Characteristics of Pogostemon cablin (Benth.)" ... book garnered No. 1 status on Amazon in several categories including: Mind-Body Medicine, ...
Breaking Biology Technology:
Cached News: