HOME >> BIOLOGY >> NEWS
Scientists At The Scripps Research Institute And R.W. Johnson Pharmaceuticals Develop New Antibacterial Agents

La Jolla, CA. April 28, 1998 -- Scientists at The Scripps Research Institute (TSRI) and their colleagues at the R.W. Johnson Pharmaceutical Research Institute have developed a series of new antibacterial compounds designed specifically to target the biological mechanisms by which bacteria establish an infection in the host. With resistance to antibiotics an increasing public health threat, particularly in the hospital setting, the compounds offer the potential to provide protection against Staphylococcus aureus, or staph infection, vancomycin-resistant enterococci, and penicillin-resistant Staphylococcus pneumoniae.

According to the authors of the study, James A. Hoch, Ph.D., Professor, and John M. Whiteley, Associate Professor in the Department of Molecular and Experimental Medicine, "With infectious disease continuing to be our most serious health problem, this work represents important progress in a new target area for anti-infective therapy."

The study, "Antibacterial agents that inhibit two-component signal transduction systems," by J.F. Barrett, R.M. Goldschmidt, L.E. Lawrence, B. Foleno, R. Chen, J.P. Demers, S. Johnson, R. Kanojia, J. Fernandez, J. Bernstein, L. Licata, A. Donetz, S. Huang, D.J. Hlasta, M.J. Macielag, K. Ohemeng, R. Frechette, M.B. Frosco, D.H. Klaubert, J.M. Whiteley, L. Wang, and J.A. Hoch, appears in today's issue of Proceedings of the National Academy of Sciences, USA.

Due to the overuse of antibiotics and the failure of some patients to take a proper dosage of medication, resistance to antibiotics is becoming an increasing risk to public health. In May, 1997, the Centers for Disease Control and Prevention confirmed that Staphylococcus aureus had for the first time defended itself against vancomycin, the last drug reported to kill all of its strains. That strain, found in Japan, demonstrated an "intermediate" level of resistance to the antibiotic, a le
'"/>

Contact: Robin B. Goldsmith
rgoldsmi@scripps.edu
(619) 784-8134
Scripps Research Institute
28-Apr-1998


Page: 1 2

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... 30, 2017  On April 6-7, 2017, Sequencing.com will ... hackathon at Microsoft,s headquarters in ... focus on developing health and wellness apps that provide ... the Genome is the first hackathon for personal ... largest companies in the genomics, tech and health industries ...
(Date:3/28/2017)... , March 28, 2017 ... Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video ... and Region - Global Forecast to 2022", published by ... in 2016 and is projected to reach USD 75.64 ... 2017 and 2022. The base year considered for the ...
(Date:3/23/2017)... March 23, 2017 The report "Gesture Recognition and Touchless ... and Geography - Global Forecast to 2022", published by MarketsandMarkets, the market is ... of 29.63% between 2017 and 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... ... wash is a basic first aid supply for any work environment, but most personal eye ... first if a dangerous substance enters both eyes? It’s one less decision, and likely quicker ... eye piece. , “Whether its dirt and debris, or an acid or alkali, getting anything ...
(Date:10/11/2017)... ... , ... Disappearing forests and increased emissions are the main causes of the ... Especially those living in larger cities are affected by air pollution related diseases. , ... pollution-affected countries globally - decided to take action. , “I knew I had to ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of ... award for Excellence in Volunteer Experience from US2020. , US2020’s mission is to ...
(Date:10/10/2017)... PITTSBURGH, PA (PRWEB) , ... October 10, 2017 ... ... this year’s recipients of 13 prestigious awards honoring scientists who ... be presented in a scheduled symposium during Pittcon 2018, the world’s leading conference ...
Breaking Biology Technology:
Cached News: