Scientists Sequence Chlamydia Trachomatis Genome

t in pelvic inflammatory disease (PID), an infection of the upper reproductive tract. The resulting tubal scarring leads to infertility, tubal pregnancy and chronic pelvic pain. Chlamydial infection also increases the risk for HIV infection.

Researchers have found the study of C. trachomatis challenging because unlike most bacteria, this organism only grows inside the host cell, just like a virus. Also, many aspects of C. trachomatis - its physiology, structure, developmental biology and genetics - are poorly understood. Its genome, however, has already revealed some extraordinary secrets. Over time, it appears that this bacterium has borrowed genetic information from its human hosts, and it uses this information to tap the resources of the cells and get essential nutrients that it cannot make.

"The Chlamydia trachomatis genome represents a molecular gold mine for the research community," says Dr. Stephens. "Even the establishment of a genetic system, which we can manipulate to study the organism, is within reach. This would enable scientists to use molecular tools to investigate, for example, how the organism gets inside the cells, how it causes scarring and how Chlamydia might escape the effects of antibiotic therapy."

The last few years have yielded critical advances in the battle against this devastating STD. A highly sensitive and specific urine test to diagnose the illness has been developed. The pharmaceutical industry has made a safe and effective single-dose oral therapy. NIAID-funded researchers have used these new tools to document the enormous problem in adolescent populations and to show that early screening and treatment for chlamydial infection can prevent PID.

"Despite significant progress, the more we look, the more chlamydial infections we find. Clearly we need better prevention tools if we are going to stop the spread of this silent plague," says Penelope J. Hitchcock, D.V.M., chief of NIAID's STD branch. "Of particul

Contact: Laurie K. Doepel
NIH/National Institute of Allergy and Infectious Diseases

Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:

(Date:6/13/2019)... ... June 13, 2019 , ... KICVentures announced today its plans to ... and Pain Management-Driven ASC Conference in Chicago on Thursday, June 13th at 6:30 pm. ... Chicago, IL in the 3rd floor Ticino Hospitality room in space #74T. , The ...
(Date:6/6/2019)... ... June 05, 2019 , ... MedTech ... the global health and medical technology market, announced that it has selected Medacta ... Robotics Solution” award in the 2019 MedTech Breakthrough Awards program. , ...
(Date:6/4/2019)... ... June 04, 2019 , ... Molecular Devices, a global leader ... the new President of Molecular Devices, replacing Greg Milosevich who has been appointed ... , Since joining Molecular Devices in a scientific engineering role, Ms. Murphy has ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... May 29, 2019 , ... For many years, the primary ... of cancer demand breakthrough therapies. Advances in immuno-oncology have led to the advent of ... cells with engineered T cell receptors known as “CARs”. The CAR enables the final ...
(Date:5/22/2019)... ... 22, 2019 , ... Artemis (formerly Agrilyst), the leading enterprise Cultivation ... round co-led by Astanor Ventures and Talis Capital with participation ... iSelect Fund . The company has raised $11.75m to date and will use the ...
(Date:5/14/2019)... Calif. (PRWEB) , ... May 14, 2019 , ... ... office expansion, effectively doubling its space from 2,500 to 5,000 square feet. , ... Early Gender DNA tests ,” says Gateway Genomics CEO, Chris Jacob. “The SneakPeek At-Home ...
(Date:5/2/2019)... BELTSVILLE, Md. (PRWEB) , ... ... ... certification to the International Organization for Standardization ISO 9001:2015 standard, REPROCELL USA ... consistently meet customer requirements. In addition, REPROCELL USA Inc. aims to enhance ...
Breaking Biology Technology:
Cached News: