HOME >> BIOLOGY >> NEWS
Scientists Study Protein's Role In Tumor Development In Fish

ATHENS, Ohio -- Studies of a protein implicated in the development of skin tumors in fish could lead to a better understanding of a similar protein's role in breast and other human cancers, according to researchers at Ohio University.

Scientists have been exploring the role cyclin D, a protein that regulates cell replication, plays in the development and death of tumors found on walleye, a North American freshwater fish. The skin tumors, walleye dermal sarcoma, appear and disappear seasonally, says Don Holzschu, assistant professor of molecular biology at Ohio University and a lead researcher on the project.

First reported in a National Cancer Institute monograph in 1969, these tumors -- which appear in the fall and die during the spring spawning season -- seem to pose no health risk to humans, according to officials with Ohio Sea Grant. Walleye infected with the tumors have been reported in rivers and lakes throughout North America, including in Ohio, New York and Canada.

Researchers suspect infected walleye spread the virus that causes the tumors during the spawning season, when all the fish are grouped together. "It's just like sending your child to daycare," Holzschu says. "It's a perfect time to spread the virus." It's thought that the virus grows over the summer and tumors begin to appear in the fall. By spring, the tumors are dying and the infection is passed to other fish.

While the seasonal nature of the tumors is enough to keep the scientists' interest, new studies have added to their fascination with this project. In their analysis of the viruses that cause walleye dermal sarcoma and another skin disease, walleye dermal hyperplasia, researchers have discovered the culprits for these infections are three retroviruses that are unlike any ever studied.

A retrovirus is a virus that has RNA as its nucleic acid and uses the enzyme reverse transcriptase to copy its genome into the DNA, whic
'"/>

Contact: Melissa Rake
rake@ohio.edu
740-593-1891
Ohio University
3-Mar-1999


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists Study Protein Role Tumor Development Fish

(Date:10/29/2014)... both genetic and environmental, have been blamed for ... Some, such as a family history of schizophrenia, ... Toxoplasma gondii , a parasite transmitted by ... viewed with skepticism. , A new study by ... at the University of Pennsylvania,s School of Veterinary ...
(Date:10/29/2014)... household and industrial products are in the environment – ... of them, scientists have yet to determine whether they ... toward doing that by estimating which substances people are ... in the ACS journal Environmental Science & Technology ... the risks to human health of any given substance ...
(Date:10/29/2014)... held in New York City on September 19, 2014, ... Cancer Society Professor of Genome Sciences and Medicine at ... Doctor of Philosophy of Tel Aviv University, was awarded ... , In addition to her honorary degree from TAU, ... TAU School of Medicine, and for the past 18 ...
Breaking Biology News(10 mins):Penn vet professor investigates parasite-schizophrenia connection 2Penn vet professor investigates parasite-schizophrenia connection 3Geneticist and humanitarian: Prof. Mary-Claire King receives Lasker Award 2
(Date:10/31/2014)... York, NY (PRWEB) October 31, 2014 ... such as healthcare, construction, finance and consumer electronics ... For this reason, industry research firm IBISWorld has ... industry to its growing industry report collection. , ... develop software for biometric technologies such as fingerprint, ...
(Date:10/30/2014)...  Ardelyx, Inc. (NASDAQ: ARDX ), ... and metabolic diseases, today announced that it will ... November 6, 2014. Following the announcement, the Ardelyx ... and webcast at 4:30pm ET to review the ... The live webcast can be accessed ...
(Date:10/30/2014)... CA (PRWEB) October 30, 2014 ... today that they have manually curated public data source ... non profit customers. the data is now available ... curates and unifies public and internal data sources for ... and knowledge out of the data that becomes more ...
(Date:10/30/2014)... Grace Century portfolio project, Provia Laboratories , ... the Board, to the National Stem Cell Ethics Committee ... by the Ministry of Health on behalf of the Government ... More than a year after Bahamian Parliament passed the ... Christie said the government has completed the accompanying regulations and ...
Breaking Biology Technology:Biometrics Scan Software in the US Industry Market Research Report Now Available from IBISWorld 2Biometrics Scan Software in the US Industry Market Research Report Now Available from IBISWorld 3Ardelyx to Report Third Quarter 2014 Financial Results on November 6, 2014 2Rancho BioSciences Manually Curated TCGA Data Sets Available 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3
Cached News: