HOME >> BIOLOGY >> NEWS
Scientists Study Protein's Role In Tumor Development In Fish

ATHENS, Ohio -- Studies of a protein implicated in the development of skin tumors in fish could lead to a better understanding of a similar protein's role in breast and other human cancers, according to researchers at Ohio University.

Scientists have been exploring the role cyclin D, a protein that regulates cell replication, plays in the development and death of tumors found on walleye, a North American freshwater fish. The skin tumors, walleye dermal sarcoma, appear and disappear seasonally, says Don Holzschu, assistant professor of molecular biology at Ohio University and a lead researcher on the project.

First reported in a National Cancer Institute monograph in 1969, these tumors -- which appear in the fall and die during the spring spawning season -- seem to pose no health risk to humans, according to officials with Ohio Sea Grant. Walleye infected with the tumors have been reported in rivers and lakes throughout North America, including in Ohio, New York and Canada.

Researchers suspect infected walleye spread the virus that causes the tumors during the spawning season, when all the fish are grouped together. "It's just like sending your child to daycare," Holzschu says. "It's a perfect time to spread the virus." It's thought that the virus grows over the summer and tumors begin to appear in the fall. By spring, the tumors are dying and the infection is passed to other fish.

While the seasonal nature of the tumors is enough to keep the scientists' interest, new studies have added to their fascination with this project. In their analysis of the viruses that cause walleye dermal sarcoma and another skin disease, walleye dermal hyperplasia, researchers have discovered the culprits for these infections are three retroviruses that are unlike any ever studied.

A retrovirus is a virus that has RNA as its nucleic acid and uses the enzyme reverse transcriptase to copy its genome into the DNA, whic
'"/>

Contact: Melissa Rake
rake@ohio.edu
740-593-1891
Ohio University
3-Mar-1999


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... -- The Allen Institute for Cell Science today announces the ... and dynamic digital window into the human cell. The ... of deep learning to create predictive models of cell ... growing suite of powerful tools. The Allen Cell Explorer ... available resources created and shared by the Allen Institute ...
(Date:4/5/2017)... LONDON , April 4, 2017 KEY ... is anticipated to expand at a CAGR of 25.76% ... neurodegenerative diseases is the primary factor for the growth ... full report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The ... of product, technology, application, and geography. The stem cell ...
(Date:4/3/2017)... , April 3, 2017  Data ... precision engineering platform, detected a statistically significant ... product prior to treatment and objective response ... the potential to predict whether cancer patients ... to treatment, as well as to improve ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... first-ever genomics analysis platform specifically designed for life science researchers to analyze ... pioneering researcher Rosalind Franklin, who made a major contribution to the discovery ...
(Date:10/11/2017)... YORBA LINDA, CA (PRWEB) , ... October 11, ... ... adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and ... activation (CRISPRa) system with small RNA guides is transformative for performing systematic gain-of-function ...
(Date:10/11/2017)... Alto, CA, USA (PRWEB) , ... October 11, 2017 , ... ... set to take place on 7th and 8th June 2018 in San Francisco, CA. ... policy influencers as well as several distinguished CEOs, board directors and government officials from ...
(Date:10/11/2017)... 2017  VMS BioMarketing, a leading provider of patient support ... Nurse Educator (CNE) network, which will launch this week. The ... health care professionals to enhance the patient care experience by ... other health care professionals to help women who have been ... ...
Breaking Biology Technology:
Cached News: