HOME >> BIOLOGY >> NEWS
Scientists Study Protein's Role In Tumor Development In Fish

ATHENS, Ohio -- Studies of a protein implicated in the development of skin tumors in fish could lead to a better understanding of a similar protein's role in breast and other human cancers, according to researchers at Ohio University.

Scientists have been exploring the role cyclin D, a protein that regulates cell replication, plays in the development and death of tumors found on walleye, a North American freshwater fish. The skin tumors, walleye dermal sarcoma, appear and disappear seasonally, says Don Holzschu, assistant professor of molecular biology at Ohio University and a lead researcher on the project.

First reported in a National Cancer Institute monograph in 1969, these tumors -- which appear in the fall and die during the spring spawning season -- seem to pose no health risk to humans, according to officials with Ohio Sea Grant. Walleye infected with the tumors have been reported in rivers and lakes throughout North America, including in Ohio, New York and Canada.

Researchers suspect infected walleye spread the virus that causes the tumors during the spawning season, when all the fish are grouped together. "It's just like sending your child to daycare," Holzschu says. "It's a perfect time to spread the virus." It's thought that the virus grows over the summer and tumors begin to appear in the fall. By spring, the tumors are dying and the infection is passed to other fish.

While the seasonal nature of the tumors is enough to keep the scientists' interest, new studies have added to their fascination with this project. In their analysis of the viruses that cause walleye dermal sarcoma and another skin disease, walleye dermal hyperplasia, researchers have discovered the culprits for these infections are three retroviruses that are unlike any ever studied.

A retrovirus is a virus that has RNA as its nucleic acid and uses the enzyme reverse transcriptase to copy its genome into the DNA, whic
'"/>

Contact: Melissa Rake
rake@ohio.edu
740-593-1891
Ohio University
3-Mar-1999


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... , April 28, 2016 First quarter 2016: ... up 966% compared with the first quarter of 2015 ... SEK 589.1 M (loss: 18.8) and the operating margin was 40% ... 0.32) Cash flow from operations was SEK 249.9 M ... revenue guidance is unchanged, SEK 7,000-8,500 M. The operating ...
(Date:4/19/2016)... , UAE, April 20, 2016 ... implemented as a compact web-based "all-in-one" system solution for ... biometric fingerprint reader or the door interface with integration ... modern access control systems. The minimal dimensions of the ... readers into the building installations offer considerable freedom of ...
(Date:4/14/2016)... TEL AVIV, Israel , April 14, 2016 /PRNewswire/ ... in Behavioral Authentication and Malware Detection, today announced the ... has already assumed the new role. Goldwerger,s ... for BioCatch, on the heels of the deployment of ... In addition, BioCatch,s behavioral biometric technology, which discerns unique ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Wausau, WI (PRWEB) , ... June 23, 2016 ... ... probiotic supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, ... supplements for over 35 years, is proud to add Target to its list ...
(Date:6/23/2016)... Lawrence, MA (PRWEB) , ... June 23, 2016 ... ... the Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research ... test platform of microbial tests introduced last year,” stated Bob Salter, Vice President ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample tracking ... Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application Specialist. ... Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our capacity as ...
(Date:6/23/2016)... June 23, 2016 On Wednesday, June ... 4,833.32, down 0.22%; the Dow Jones Industrial Average edged 0.27% ... at 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on the ... Nektar Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals Inc. ... BIND ). Learn more about these stocks by ...
Breaking Biology Technology:
Cached News: