La Jolla, CA, April 12, 2001 Scientists at The Scripps Research Institute (TSRI), have developed a screening method, similar to a home pregnancy test, that can detect mercury contamination in fish. According to Kim D. Janda, Ph.D., Eli R. Callaway Chair in Chemistry and Professor, The Skaggs Institute for Chemical Biology, the strategy could be used both by consumers and environmental professionals.
The article, "Practical Screening of Mercury Contamination in Fish Tissue," by Oliver Brummer, James J. La Clair, and Kim D. Janda, is published in the April 2001 issue of Bioorganic & Medicinal Chemistry.
"It's fast and very inexpensive," Janda says, adding that more than one million assays can be prepared in less than a week for just a few hundred dollars. For consumers, he continues, the method could be safe and easy to use. "You could buy your fish in the morning and have tested it by the time you're ready to cook that evening."
Mercury in fish is a serious health hazard, especially for children and pregnant women, because one particularly poisonous form, methylmercury, interferes with developing nervous systems and can cause birth defects. Methylmercury contamination occurs when mercury pollution from automobile emissions or industrial waste washes into the ocean or groundwater. There, aquatic organisms convert normal mercury ions into methlymercury and release the compound into the water.
Fish absorb it through their gills, or through their digestive tracts when they feed, and the poison accumulates in their tissue. Larger fish are the most risky because they eat smaller fish and have longer life spans during which the methylmercury can build up.
In recent months, the Environmental Protection Agency (EPA) has issued a warning to women who are pregnant or who are considering becoming pregnant. The EPA cautions them to avoid eating the larger, high-risk fish, such as swordfish, king mackerel and tilefish. The Food and Drug Administration
Contact: Robin B. Goldsmith
Scripps Research Institute