HOME >> BIOLOGY >> NEWS
Scientists crack genome sequence of a major parasitic pathogen

MINNEAPOLIS / ST. PAUL (March 25, 2004) -- University of Minnesota researchers have completed sequencing the genome of an intestinal parasite that affects healthy humans and animals and that can be fatal to those with compromised immune systems, such as AIDS patients. The results will be published in the journal Science on March 25.

The parasite, Cryptosporidium parvum, is considered a major public health threat for which there is currently no known treatment or prevention. The gene sequencing will allow researchers to develop new ways of early diagnosis, prevention, and treatment of this parasite.

"This is a horrible, hard to treat condition, largely because we lack a basic understanding of the genetic makeup of the organism," said Mitchell Abrahamsen, Ph.D., principal investigator, and faculty member of the University of Minnesota College Veterinary Medicine. "In fact, since analyzing the complete genome sequence, we now realize that many of the conventional antiparasitic drugs that have been used in an attempt to treat infected individuals have failed because the biochemical targets of the drugs are absent in C. parvum."

Cryptosporidum is spread through feces of infected hosts and results in an acute case of diarrhea in humans and animals. Most people with an intact immune system recover after several days; however, for the young, elderly, and immunosuppressed individuals, symptoms can be severe and require intravenous fluid therapy to deal with the resulting dehydration.

Infection by Cryptosporidium is also one of the major causes of neonatal diarrhea in calves, contributing to significant economic loss in the dairy and beef cattle industries. In 1992, a USDA study revealed that more than 80 percent of farms surveyed were positive for Cryptosporidium.

Despite intensive efforts over the past 20 years, public health authorities have found prevention difficult. The parasite is highly resistant to environmental stresses, inc
'"/>

Contact: Brenda Hudson
bhudson@umn.edu
612-624-5680
University of Minnesota
25-Mar-2004


Page: 1 2

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/27/2019)... (PRWEB) , ... November 26, 2019 , ... ... patients to their Glen Ellyn, IL practice for Invisalign® treatment. Invisalign ... teeth. , Patients with a misaligned bite, also known as malocclusion, present both ...
(Date:11/22/2019)... ... 21, 2019 , ... The inventors of a new and ... major step forward with that therapy, known as SurVaxM. MimiVax LLC principals Robert ... from Roswell Park in 2012, has entered into a China-exclusive licensing agreement for ...
(Date:11/19/2019)... , ... November 19, 2019 , ... ... and sample preparation, and Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global ... in which Diagenode will offer Single-Cell ATAC-Seq (scATAC-Seq) Services, featuring Bio-Rad’s Droplet Digital ...
Breaking Biology News(10 mins):
(Date:12/4/2019)... S.D. (PRWEB) , ... December 04, 2019 , ... The ... smaller than a human hair, but its potential impact on the pharmaceutical industry could ... a professor of biological and chemical engineering at South Dakota School of Mines ...
(Date:11/22/2019)... , ... November 21, 2019 , ... Lajollacooks4u is preparing ... and cooking events company already scheduled several of its popular cooking classes and team-building ... , The company’s Holiday Parties have been a favorite for companies of ...
(Date:11/12/2019)... , ... November 12, 2019 ... ... enterprise software solutions for biopharmaceutical R&D, today announced that Immatics Biotechnologies ... adopted Genedata Biologics® to streamline their R&D operations related to ...
(Date:11/9/2019)... (PRWEB) , ... November 08, ... ... of artificial intelligence (AI)-powered technology for use in pathology research, today announced ... liver biopsy samples from patients enrolled in the phase 3 selonsertib studies ...
Breaking Biology Technology:
Cached News: