HOME >> BIOLOGY >> NEWS
Scientists create smart mouse

Addition of single gene improves learning and memory

PRINCETON, N.J. -- In an achievement that one day may give scientists the ability to boost human intelligence, Princeton University researchers reported today that they have genetically modified mice to have improved learning and memory.

Neurobiologist Joe Tsien, with collaborators at MIT and Washington University, found that adding a single gene to mice significantly boosted the animals' ability to solve maze tasks, learn from objects and sounds in their environment and to retain that knowledge. This strain of mice, named Doogie, also retained into adulthood certain brain features of juvenile mice, which, like young humans, are widely believed to be better than adults at grasping large amounts of new information.

The work, reported in the September 2 issue of Nature, is a breakthrough in memory research and reveals a common biochemical mechanism at the root of nearly all learning. It shows that the brain uses the same basic tool when it forms associations, even though parts of the brain work in specialized ways and deal with diverse types of information, such as sights, sounds and touch. The result gives scientists confirmation of a long-standing theory about how we learn and remember, an idea posed in 1949 by Donald O. Hebb that had been central to memory research.

The finding also shows that genetic improvement of intelligence and memory in mammals is now feasible, thus offering a striking example of how genetic technology may affect mankind and society in the next century.

"Joe is doing some really interesting and fundamental work," said Ira Black, chairman of neuroscience and cell biology at Rutgers University. "It's a novel approach. It's very exciting and holds the hope of not only making animals smarter, but also, ultimately of having a (human) gene therapy for use in are
'"/>

Contact: Steven Schultz
sschultz@princeton.edu
609-258-5729
Princeton University
2-Sep-1999


Page: 1 2 3 4 5 6

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists create smart mouse

(Date:12/19/2014)... MOUNTAIN VIEW, Calif. , Dec. 18, 2014  23andMe, Inc., ... a study that pinpoints fine-scale differences in genetic ancestry of ... Since immigrants first arrived more than four hundred ... served as a meeting place for peoples from different continents. ...
(Date:12/17/2014)... SM announced today its completion of a Good ... current U.S. Food and Drug Administration (FDA) regulations. This ... smart phone application trials utilizing the highest principles for ... determined to improve global healthcare access, quality, and delivery ...
(Date:12/15/2014)... Dec. 12, 2014 Research and Markets ( ... "Global Facial Recognition Market 2015-2019" report to their ... Facial recognition is a technology used for the ... facial feature of a person such as nose, jaw ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
(Date:1/23/2015)... Biofertilizers stimulate microbial activities in soil. These ... through the activities in the soil or in the ... the stress on reducing environmental pollution and on reducing ... and segments the bio fertilizers market with analysis and ...
(Date:1/22/2015)... today announces the firm brokered a long-term lease totaling 202,492 ... company, at Two Ledgemont Center in Lexington, Massachusetts ... and Brian Cohen , senior vice president, represented Shire ... Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... Johnston, RI (PRWEB) January 22, 2015 ... State , The growing team of brand-neutral, independent consultants, ... CIO Philip Rogers explained that over the years, his ... including , Moroso, Town of Plainfield, as well as ...
(Date:1/22/2015)... Wilmington, DE (PRWEB) January 22, 2015 ... the Pistoia Alliance, which helps companies check the legal ... set to expand to China. , As their ... companies are globally adopting software solutions built as a ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Global Compliance Service for Controlled Substances to Expand to China 2
Cached News: