HOME >> BIOLOGY >> NEWS
Scientists discover how to grow cells that suppress immune responses

growing Tr1 cells in culture dishes for several days, drawing off some of the fluid bathing the cells and adding that fluid to other dishes containing activated, proliferating infection-fighting T cells. The fluid, which contained IL-10 produced by the Tr1 cells, shut down the growth and activity of the T cells.

That was a very good day, says Kemper. IL-10 is the classic substance that suppresses the action and proliferation of other immune cells.

The investigators next want to study how CD46 triggers production of IL-10 and to better define the population of cells that give rise to Tr1 cells. They also want to explore how viruses, including those that cause measles, meningitis and herpes, interact with CD46.

Its tempting to think that these pathogens dock with CD46 because it causes some cells to produce IL-10, which would suppress the action of nearby immune cells and help the pathogen survive, says Kemper. We can investigate such questions because we can now grow these cells in the laboratory.


'"/>

Contact: Darrell E. Ward
wardd@msnotes.wustl.edu
314-286-0122
Washington University School of Medicine
22-Jan-2003


Page: 1 2

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists discover how grow cells that suppress immune responses

(Date:4/22/2014)... in two Minnesota cities demonstrate how communities can ... a ten year program in New England and ... to local conditions. , "Our goal is to ... said program co-leader Latham Stack, of Syntectic International, ... worsened. We help communities move beyond feeling paralyzed ...
(Date:4/21/2014)... is commonly used as a farm soil fertilizer, contains ... from the cows, gut bacteria. The findings, reported in ... American Society for Microbiology, hints that cow manure is ... genes that transfer to bacteria in the soils where ... (AR) genes have already been identified, but the vast ...
(Date:4/21/2014)... are on the decline in the Galpagos. , A new ... indicates numbers of the iconic birds, known for their ... attract mates, have fallen more than 50 percent in less ... is probably due to an unexplained disappearance of sardines from ... at Wake Forest University and the study,s principal investigator. This ...
Breaking Biology News(10 mins):Minnesota projects offer hope and practical help to communities facing more extreme storms 2Cow manure harbors diverse new antibiotic resistance genes 2Cow manure harbors diverse new antibiotic resistance genes 3Lack of breeding threatens blue-footed boobies' survival 2Lack of breeding threatens blue-footed boobies' survival 3
(Date:1/15/2014)... The Pittcon Organizing Committee is pleased to announce that ... an e-Journal and producer of Food Labs Conference ... for the co-location of Food Labs Conference to be held ... registration fee to attend the two-day Food Lab Conference, March ...
(Date:1/15/2014)... 2014 Look inside the new Preferred ... the lab, from fluid handling to instruments to supplies. ... when you order. , Preferred Solutions features a ... the L/S® model for precise flow control and dispensing ...
(Date:1/15/2014)... California , January 15, 2014 Oxford ... today announced the appointment of Thomas C Reynolds MD, PhD ... years, development experience gained in the biotechnology industry, most recently ... am delighted to welcome Tom at this transformative time for ...
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2
Cached News: