HOME >> BIOLOGY >> NEWS
Scientists discover potential approaches to enhance existing cancer therapies

Scientists today reported exciting discoveries to optimize existing cancer treatments. One set of studies demonstrated that the cell-killing effects of either radiation or standard chemotherapy drugs were enhanced when tumor cells such as melanoma were grown in dishes containing PABA, an ingredient in some sunscreens. In a separate study, researchers presented an advanced imaging technique that may help physicians select which recurrent breast cancer patients are most likely to respond to hormonal therapy. The studies were presented today at the International Conference on Molecular Targets and Cancer Therapeutics organized by the American Association of Cancer Research (AACR), National Cancer Institute (NCI) and European Organisation for Research and Treatment of Cancer (EORTC) in Boston.

In vitro and in vivo radiosensitization by p-aminobenzoic acid (PABA): Abstract 1005

A research team from New York University School of Medicine analyzed the effects of PABA and radiation alone and together on several cancer cell lines grown in laboratory dishes, as well as on implanted tumors in mice and chick embryos. In each of the experiments, they discovered that when PABA and radiation were administered together, tumor growth was substantially reduced compared to treatment with either radiation or PABA alone. In another set of experiments, they evaluated the ability of PABA to improve the effects of certain chemotherapy drugs. Again, the addition of PABA significantly improved the anti-tumor effects of drugs such as Taxol.

"These early findings suggest that PABA may optimize current cancer treatments by making tumor cells more vulnerable to certain chemotherapeutic drugs and radiation," says Peter Brooks, Ph.D., associate professor of radiation oncology and cell biology at NYU School of Medicine, who presented the results today. "We will continue to assess the cellular basis for PABA's effects."

Although it isn't yet clear how PABA
'"/>

Contact: Warren Froelich
froelich@aacr.org
215-440-9300
American Association for Cancer Research
19-Nov-2003


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: