HOME >> BIOLOGY >> NEWS
Scientists document water molecule movement across cell walls

CHAMPAIGN, Ill. Scientists have documented a ballet in which dancers cross the stage in a billionth of a second. The stage is a class of proteins found in all living things; the dancers are water molecules. The performance, captured by supercomputer simulation, casts new insight for biomedical researchers on the controlled movement of water through cell walls.

Reporting in the April 19 issue of Science, researchers at the University of Illinois Beckman Institute for Advanced Science and Technology and at the University of California at San Francisco say the orientation of water molecules moving through aquaporins assures that only water, not ions such as protons, permeates between cells. If the latter occurs, energy stored as electrical potential between the inside and outside of the cell wall is lost.

Aquaporins, a class of proteins, form transmembrane channels found in cell walls. Plants have 35 different proteins of this type. Mammals, including humans, have 10, with many of them in the kidney, brain and lens of the eye.

When working correctly, said Klaus Schulten, the Swanlund Professor of Physics at the UI, the transport of water between plant cells lets flowers bloom and leaves stand sturdily, for example. In mammals, the machinery processes water efficiently to help maintain optimum health. A breakdown in human kidneys, the busiest water-handling organ with 400 liters being pumped through daily, leads to diabetes insipidus, in which water is not reabsorbed and abnormally large volumes of dilute urine are produced. Breakdowns in other organs can lead to loss of hearing and cataracts.

The structure of aquaporins was determined two years ago by Robert M. Stroud and colleagues at UCSF, who determined the geometry of the protein in the bacterium E. coli (GlpF).

However, Shulten said, that work still could not resolve exactly how water is conducted in the channel, and how it prevents the conduction of ions. Crystall
'"/>

Contact: Jim Barlow
b-james3@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
18-Apr-2002


Page: 1 2

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2017)... , April 18, 2017  Socionext Inc., a global expert ... a media edge server, the M820, which features the company,s hybrid ... software provided by Tera Probe, Inc., will be showcased during the ... the NAB show at the Las Vegas ... ...
(Date:4/11/2017)... April 11, 2017 Crossmatch®, a globally-recognized ... solutions, today announced that it has been awarded ... Projects Activity (IARPA) to develop next-generation Presentation Attack ... "Innovation has been a driving force within ... will allow us to innovate and develop new ...
(Date:4/6/2017)... -- Forecasts by Product Type (EAC), Biometrics, ... (Transportation & Logistics, Government & Public Sector, Utilities / ... Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality ... looking for a definitive report on the $27.9bn Access ... ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... ... technology applications, has announced a facility expansion to accommodate its rapid growth. , ... of new workspace and renovation of the existing areas. The expansion includes, a ...
(Date:5/23/2017)... ... ... Cambridge Semantics , the leading provider of Big Data management and ... Expo in Boston May 23-25 with a featured speaker and solution demos of ... is also a finalist for the Best of Show award. , James LaPointe, Managing ...
(Date:5/22/2017)... ... 22, 2017 , ... Baltimore biotech firm, PathSensors, announced that ... in developing and issuing recommendations to grow Maryland's biohealth industry and position the ... , The recommendations are contained in a report from the ...
(Date:5/21/2017)... CA (PRWEB) , ... May 20, 2017 , ... ... tool that helps avoid the lengthy trial and error process by finding the ... It can also strengthen the doctor-patient relationship through a personalized approach to ...
Breaking Biology Technology:
Cached News: