HOME >> BIOLOGY >> NEWS
Scientists find nanowires capable of detecting individual viruses

CAMBRIDGE, Mass., Sept. 22, 2004 - Harvard University scientists have found that ultra-thin silicon wires can be used to electrically detect the presence of single viruses, in real time, with near-perfect selectivity. These nanowire detectors can also differentiate among viruses with great precision, suggesting that the technique could be scaled up to create miniature arrays easily capable of sensing thousands of different viruses.

The work was reported in the most recent issue of the Proceedings of the National Academy of Sciences.

"Viruses are among the most important causes of human disease and are of increasing concern as possible agents of biowarfare and bioterrorism," says author Charles M. Lieber, Mark Hyman Jr. Professor of Chemistry in Harvard's Faculty of Arts and Sciences. "Our work shows that nanoscale silicon wires can be configured as ultra-sensitive detectors that turn on or off in the presence of a single virus. The capabilities of nanowire detectors, which could be fashioned into arrays capable of detecting literally thousands of different viruses, could usher in a new era for diagnostics, biosafety, and response to viral outbreaks."

Lieber and his colleagues merged nanowires conducting a small current with antibody receptors for certain key domains of viruses - such as agglutinin in the influenza A virus. When an individual virus came into contact with a receptor, it sparked a momentary, telltale change in conductance that gave a clear indication of the virus's presence. Simultaneous electrical and optical measurements using fluorescently labeled influenza A confirmed that these conductance changes corresponded to binding and unbinding of single viruses from nanowire devices.

In addition to influenza A, the Lieber group tested nanowire arrays outfitted with receptors specific to paramyxovirus and adenovirus. The researchers found the detectors could differentiate among the three viruses both because of the sp
'"/>

Contact: Steve Bradt
steve_bradt@harvard.edu
617-496-8070
Harvard University
22-Sep-2004


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists discover potential new way to control drug-resistant bacteria
4. Scientists explore genome of methane-breathing microbe
5. Scientists decipher genetic code of biothreat pathogen
6. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
7. Scientists discover proteins involved in spread of HIV-1 infection
8. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
9. Scientists reinvent DNA as template to produce organic molecules
10. Scientists visualise cellular handmaiden that restores shape to proteins
11. Scientists identify compounds that mimic calorie restriction

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/6/2019)... Va. (PRWEB) , ... November 06, 2019 , ... ... today that Donald Stanski, MD, a senior pharmaceutical industry executive with expertise in ... and simulation for drug and disease strategic data analytics, has joined the firm ...
(Date:11/5/2019)... ... November 05, 2019 , ... Dr. Lauren Kopp celebrates ... to Seattle, WA, including porcelain veneers , smile makeovers, dental implants, and ... of Washington, Dr. Kopp is passionate about serving her Seattle community with empathy ...
(Date:10/30/2019)... Va. (PRWEB) , ... October 30, 2019 , ... ... offering from the Farm Credit Knowledge Center in which participants will learn about ... industry best practice relating to these technologies. , Participants will have the ...
Breaking Biology News(10 mins):
(Date:11/2/2019)... ... October 31, 2019 , ... A clinical ... with each other: study managers, principal investigators, supply chain managers, manufacturers, IRT, CRAs ... not informed of the latest data, potentially leading to patient risk. , By ...
(Date:10/29/2019)... ... 2019 , ... CaroGen Corporation , a biotechnology company, today announced three ... Jack R Wands, MD, of Brown University , Dr. Steve Projan, PhD, ... MD, PhD, of Wayne State University, formerly a professor at Yale University School of ...
(Date:10/22/2019)... ... October 22, 2019 , ... Catalent, a global leader in clinical supply services, ... Integration, will participate in a panel session titled “Cell and Gene Therapy Logistics” at ... Gwen Hotel, Chicago, on Oct. 28-30, 2019. , The panel session, on Wednesday, Oct. ...
(Date:10/15/2019)... , ... October 14, 2019 , ... ARPR , an award-winning tech PR agency ... honored as a Health Care Agency of the Year in the Ragan’s Health Care ... as a finalist by Ragan’s. The firm also revealed today that its healthIT practice group ...
Breaking Biology Technology:
Cached News: