HOME >> BIOLOGY >> NEWS
Scientists prove mature adult cells can be cloned

Researchers from Rudolf Jaenischs lab at the Whitehead Institute for Biomedical Research have taken a significant step toward answering a half century old questiondo clones, like Dolly, derived from adult cells develop from a fully mature adult cell or do they develop from rare stem cells found in adult tissues? The researchers have proved for the first time that fully differentiated adult cells can form clones, but they found the process is extremely inefficient. It is more likely that elusive adult stem cells, which exist in tiny numbers along with the mature adult cells, are actually the ones to form clones, says Jaenisch. The study was conducted by Konrad Hochedlinger, a student in the Jaenisch lab, and will appear in Nature online February 10, 2002.

"This finding tells us something about the nature of the genome of adult cellsthese cells are not very labile and difficult to clone. This is important to know, if adult cells are going to be cloned for personalized cell therapy," says Jaenisch. Therapeutic cloning involves removing the nucleus, or the genetic command center, of an egg and replacing it with the nucleus from an adult donor cell. Ideally, the egg resets the developmental clock of the nucleus back to a state compatible with early embryonic growth. This ball of cells growing in culture gives rise to embryonic stem (ES) cells that genetically match the donor and have the potential to become any tissue in the body. In theory, these ES cells may be used to treat diseases, such as diabetes or spinal cord injury, without the complications of organ rejection.

Using Immune Cells to Clone Mice

Scientists have known for sometime that cloning using ES cells is much more efficient than using adult cells, probably 10 fold more efficient. This makes sense because ES cells are at the earliest developmental stage and have the potential to become all the cells that make up an organism. But researchers didnt know if cloning could set the cloc
'"/>

Contact: Nadia Halim
halim@wi.mit.edu
617-258-9183
Whitehead Institute for Biomedical Research
10-Feb-2002


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists prove mature adult cells can cloned

(Date:4/27/2015)... 27, 2015  For more than four decades, AUVSI,s ... been the premier worldwide event for the unmanned land, ... must-attend event for any local, national, or trade news ... commercial markets and current applications of unmanned technologies. The ... projected $48 billion industry, and how it will soon ...
(Date:4/27/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces that its Wocket® ... first week of May, 2015 and will be fulfilling ... Gino Pereira , Chief Executive Officer ... as Wocket® enters the consumer market. We would like ...
(Date:4/27/2015)... LAUDERDALE, Fla. , Apr. 27, 2015 ... of access control and security systems is pleased to ... the company as a consultant and member of its ... is widely known as a thought leader in ... Distance Learning Technology Group, and has published studies and ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
(Date:4/27/2015)... HEIDELBERG , Alemania, April 27, 2015 ... un nuevo receptor utilizando tecnología de descubrimiento de biomarcador ... en el tratamiento de millones de pacientes con cáncer ... que ha recibido una patente en Europa titulada "Tissue ... de Molecular Health de que EPHB4 es un nuevo ...
(Date:4/27/2015)... (PRWEB) April 27, 2015 Dr. Robert ... and chemical toxicity carries implications for advancing the creation ... 28 at National University , the second-largest private, ... by Dr. Hanzlik, a professor at the University of ... and drug design, starts at 5 p.m. and takes ...
(Date:4/27/2015)... , April 27, 2015  Edico Genome today ... geneticists from Harvard and Stanford Universities showed the ... genome sequence with 300x depth of coverage by ... to 60 hours with standard software. ... challenge, especially for individual research and clinical labs, ...
(Date:4/27/2015)... Philadelphia, PA (PRWEB) April 27, 2015 ... Phelix Therapeutics, the newest resident of the University ... Market Street in Philadelphia. , With a $4.5 ... of Health in hand, Phelix Therapeutics is ... is developing nutritional supplements. The company is developing first-in-class ...
Breaking Biology Technology:Molecular Health obtiene la patente para un nuevo receptor 2Molecular Health obtiene la patente para un nuevo receptor 3Dr. Robert Hanzlik Discusses Pharmaceutical Testing Models at Event Hosted by National University 2Dr. Robert Hanzlik Discusses Pharmaceutical Testing Models at Event Hosted by National University 3Edico Genome, in Collaboration with Researchers from Harvard and Stanford Universities, Speeds Analysis of Whole Genome Sequence with 300x Depth of Coverage Tenfold 2Edico Genome, in Collaboration with Researchers from Harvard and Stanford Universities, Speeds Analysis of Whole Genome Sequence with 300x Depth of Coverage Tenfold 3New Resident of Science Center’s Port Business Incubator Targets SARS and Ebola 2
Cached News: