HOME >> BIOLOGY >> NEWS
Scientists prove mature adult cells can be cloned

Researchers from Rudolf Jaenischs lab at the Whitehead Institute for Biomedical Research have taken a significant step toward answering a half century old questiondo clones, like Dolly, derived from adult cells develop from a fully mature adult cell or do they develop from rare stem cells found in adult tissues? The researchers have proved for the first time that fully differentiated adult cells can form clones, but they found the process is extremely inefficient. It is more likely that elusive adult stem cells, which exist in tiny numbers along with the mature adult cells, are actually the ones to form clones, says Jaenisch. The study was conducted by Konrad Hochedlinger, a student in the Jaenisch lab, and will appear in Nature online February 10, 2002.

"This finding tells us something about the nature of the genome of adult cellsthese cells are not very labile and difficult to clone. This is important to know, if adult cells are going to be cloned for personalized cell therapy," says Jaenisch. Therapeutic cloning involves removing the nucleus, or the genetic command center, of an egg and replacing it with the nucleus from an adult donor cell. Ideally, the egg resets the developmental clock of the nucleus back to a state compatible with early embryonic growth. This ball of cells growing in culture gives rise to embryonic stem (ES) cells that genetically match the donor and have the potential to become any tissue in the body. In theory, these ES cells may be used to treat diseases, such as diabetes or spinal cord injury, without the complications of organ rejection.

Using Immune Cells to Clone Mice

Scientists have known for sometime that cloning using ES cells is much more efficient than using adult cells, probably 10 fold more efficient. This makes sense because ES cells are at the earliest developmental stage and have the potential to become all the cells that make up an organism. But researchers didnt know if cloning could set the cloc
'"/>

Contact: Nadia Halim
halim@wi.mit.edu
617-258-9183
Whitehead Institute for Biomedical Research
10-Feb-2002


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/13/2016)... New York , January 13, 2016 ... Market Research has published a new market report titled ... Growth, Trends, and Forecast, 2015 - 2023. According to the ... in 2014 and is anticipated to reach US$1,625.8 mn ... 2015 to 2023. In terms of volume, the biometric ...
(Date:1/8/2016)... and MANCHESTER, United Kingdom , Jan. ... developer of innovative sensor-based diagnostic products, today announced the closing ... new and existing investors.  Proceeds from the financing will be ... , a hand-held device for detecting early-stage pressure ulcers. ... Ireland after receiving CE Mark approval. The device,s ...
(Date:1/7/2016)... -- A United States District Court in Illinois ... to interpret a biometric privacy statute in a decision ... photo website Shutterfly brought by the law firm Carey Rodriguez ... SHUTTERFLY, INC.; and THISLIFE, INC ( N.D. Ill ., ... Illinois Biometric Privacy Act by collecting and scanning face ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... program for the development of future natural products for crop ... and development center in Israel and ... Stockton has a variety of products adapted to ... in more than 35 counties worldwide. ... product Timorex Gold ® is used to control a ...
(Date:2/5/2016)... ATCC, the premier global biological materials resource ... and life science researchers that are working to address ... CDC website . --> CDC ... a single-stranded RNA virus of the Flaviviridae family, genus ... Chikungunya Viruses. Zika virus is transmitted to humans primarily ...
(Date:2/4/2016)... ... February 04, 2016 , ... Morf Media ... announced an interactive FDA compliance training course, Writing Effective SOPs ... Society) accredited interactive course on Morf Playbook—now conveniently available on smartphones and PCs--provides ...
(Date:2/4/2016)... , Feb. 4, 2016 Beike Biotechnology, ... various medical institutions attended a ceremony in late 2015 ... personalized cell therapy in 2016. --> ... Clinical Translation Platform for Personalized Cell Therapy" was hosted ... Cell Production Center, both subsidiaries of Beike Biotechnology Co., ...
Breaking Biology Technology:
Cached News: