Scientists report important data in stem cell debate

IH's National Human Genome Research Institute, and Dr. Michael Brownstein, a scientist at NIH's National Institute of Mental Health. "I would have never been able to do this study if I had been in another type of setting," said Tran, highlighting the unique multidisciplinary environment at NIH that allows more complex studies to be undertaken.

Once the assay was up and running, the scientists discovered that all five women had cheek cells that contained both X and Y chromosomes. The range was from 0.8 percent in one woman to 12.7 percent in another. Because some of the women had sons, the scientists performed an additional DNA analysis that ruled out the possibility of the cells originating from their male offspring. The cells also tested positive for cytokeratin.

Interestingly, of the 9,700 cells that were examined in the study, only two showed signs of possible fusion. In the previous reports of cell fusion from celll culture studies, the rate was also extremely low, ranging from one every 100,000 to one million adult stem cells.

While Tran said this paper does not provide the definitive answer to the transdifferentiation debate, it does offer a higher level of evidence. "I hadn't studied stem cells previously," said Tran, who is employing tissue engineering techniques to develop an artificial salivary gland. "But I saw an opportunity to help forward the field with a model that perhaps some had overlooked. I think these data will be helpful to many."


Contact: Bob Kuska
NIH/National Institute of Dental and Craniofacial Research

Page: 1 2 3 4

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:

(Date:10/16/2018)... , ... October 16, 2018 ... ... leader in delivering cloud-based enterprise-class unified communications and collaboration solutions, announced today ... stability by directly connecting CallTower data centers to a customers’ network. CallTower’s ...
(Date:10/11/2018)... , ... October 09, 2018 , ... Exalto Bearings ... marine industries, announces the appointment of Mike Cosgrove as Business Manager. , Cosgrove has ... responsible for the day to day running of the Derby UK facility. , “We ...
(Date:10/5/2018)... ... October 05, 2018 , ... The Amino ... announcing a 10% price increase across all markets in January 2019. , ... building blocks of protein — for the parenteral nutrition, biopharmaceutical, infant/medical food, supplement ...
Breaking Biology News(10 mins):
(Date:10/5/2018)... ... 04, 2018 , ... Karius , a life sciences ... at IDWeek™ 2018 the positive results of a study demonstrating that the Karius® ... causative pathogens in patients with infective endocarditis even when blood cultures were negative ...
(Date:10/2/2018)... ... October 02, 2018 , ... ... Bio-Energy Solutions™, LLC’s (Locus Bio-Energy) AssurEOR product line was chosen for its advancements ... Gulf Energy Information, honor leading innovations in upstream oil applications that are positively ...
(Date:9/28/2018)... ... September 28, 2018 , ... LabRoots , ... and scientists from around the world, is excited to announce Daniel Andrade, a ... as the winner of the LabRoots Summer 2018 Textbook Scholarship, awarding him $1,000 ...
(Date:9/27/2018)... ... September 27, 2018 , ... ... Everwell Health Solutions and SureAdhere Mobile Technology, Inc. announced they will formally merge ... in the battle against tuberculosis (TB) and other diseases. These two social enterprise ...
Breaking Biology Technology:
Cached News: