HOME >> BIOLOGY >> NEWS
Scientists reveal details of brain cell communication: implications for learning & memory

lectrical stimulation and allow calcium to flow into dendritic spines. Calcium, in turn, triggers biochemical events in the spine which modify synaptic strength and thereby encode memories.

In their study, Sabatini and Svoboda could detect if single calcium channels opened or, by chance, remained closed following stimulation. Measuring the probability of channel opening, "like tossing a coin, where heads is open and tails is closed," says Svoboda, enabled him and Sabatini to determine the number of calcium channels per spine. The scientists discovered that depending on their size, spines contain from one to twenty, and typically three, calcium channels.

"Visually examining calcium fluctuations in a single dendritic spine in the brain as we have done is akin to examining the wrinkles on a raisin sitting on the 50 yard line of a football stadium from the Goodyear blimp," says Sabatini.

But nothing is that simple in the brain. Which type of channel is causing these changes in calcium? There are at least six known varieties of calcium channels that could be present in spines, each having different properties. Using chemical probes, Sabatini and Svoboda were able to demonstrate that one specific type of channel (the R type) is solely responsible for the influx of calcium that they observed. "We are looking at the behavior of single calcium channels in their natural environment, the brain." said Sabatini.

"The local influx of calcium we have observed in spines is a fundamental measure of the information carried in one particular brain neuron and how it is processed locally. The information encoded in the messages passed between neurons is simple," says Sabatini. "It's not unlike computer programming code where a single command can be either one for a positive response or zero for a negative response." When an action potential causes a calcium channel to open, that's a one, when it fails to open that's a zero.

Scientists beli
'"/>

Contact: Michael Stebbins
stebbins@cshl.org
516-367-8881
Cold Spring Harbor Laboratory
28-Nov-2000


Page: 1 2 3

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
(Date:10/29/2014)... stem cell, those referred to as ,facultative, form part—together ... nothing that differentiates these cells from the others. However, ... the capacity to become stem cells again. This phenomenon ... that hosts cells that stimulate tissue growth, thus allowing ... a transplant. Knowledge of the underlying mechanism that ...
(Date:10/29/2014)... – Ghrelin is a hormone released by the stomach ... commonly viewed as a psychoactive substance that primarily affects ... food. , This knowledge, combined with findings from ... has the potential to stimulate alcohol craving. , Dr. ... and found that, as they had anticipated, alcohol craving ...
(Date:10/28/2014)... German . ... sufficient food when times are lean? By studying wild ... researchers of the Max Planck Institute for Evolutionary Anthropology ... great apes can acquire extra energy needed to maintain ... sleeping nests more en route to breakfast sites containing ...
Breaking Biology News(10 mins):A mechanism that allows a differentiated cell to reactivate as a stem cell revealed 2Ghrelin stimulates an appetite for drinking alcohol 2The early chimp gets the fig 2The early chimp gets the fig 3
(Date:10/27/2014)... Cary, North Carolina (PRWEB) October 27, 2014 ... was invited earlier this month to sit down with Bryan ... Spencer from RPG Solutions to discuss talent in the Research ... the topics that were highlighted at the roundtable ... in the Triangle, the significance of work/life balance and the ...
(Date:10/27/2014)... Oct. 27, 2014 Kalorama Information says that ... concern in the United States ... healthcare market researcher said the FDA,s Emergency Use Authorization (EUA) ... tests for the detection of the Ebola virus was ... Kalorama routinely assess the IVD industry and its biennial ...
(Date:10/27/2014)... 2014 The report “Smart Highway ... Management, Communication, Monitoring), and by Display (Variable Message ... segments the global market into various sub-segments with ... identifies the drivers and restraints for this market ... Browse 75 market tables and 37 figures spread ...
(Date:10/26/2014)... The report "Data Center Networking Market [Ethernet ... Optimization Appliances]: Global Advancements, Worldwide Forecasts & Analysis ... market into various segments with an in-depth analysis ... the factors driving this market, various restraints and ... future roadmaps. , Browse 106 market data tables ...
Breaking Biology Technology:Personify's Ryan Carfley Talks Recruiting with Triangle Business Journal, RPG Solutions 2Personify's Ryan Carfley Talks Recruiting with Triangle Business Journal, RPG Solutions 3Kalorama: PCR The Go-to Test in Ebola Fight 2Kalorama: PCR The Go-to Test in Ebola Fight 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 2Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 4Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 2Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 3Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 4
Cached News: