HOME >> BIOLOGY >> NEWS
Scientists take a step nearer to creating an artificial egg using a somatic cell

Madrid, Spain: Scientists believe that they are an important step nearer to success in creating an artificial egg from the combination of the nucleus of a somatic cell and an oocyte which has had its DNA-carrying nucleus removed, a conference of international fertility experts heard today (Tuesday 1 July).

Dr Peter Nagy, from Reproductive Biology Associates, Atlanta, collaborating with the University of Connecticut, USA, told the European Society of Human Reproduction and Embryology annual conference that former approaches to haploidisation[1] using a fully mature oocyte and a resting (interphase) somatic cell had caused misaligned chromosomes during cell division. However, he was confident from his team's latest experiments that this difficulty could be overcome, even though their new approach also ran into some problems.

"We decided to initiate haploidisation at an earlier stage in the oocyte's cell cycle, when it was still immature, but this time using a somatic cell in its active (metaphase or G2/M) stage. Essentially, we took the control of the first nuclear division away from the oocyte and gave it to the somatic cell," he said.

The US-Brazilian research team[2] , working with mouse cells, removed the nucleus of the immature oocyte, then transformed the somatic cell from its diploid (46 chromosome or 2n) stage to its next (4n) stage and transferred it to the immature enucleated oocyte (ooplast).

"What we expected by doing this was that the DNA in the somatic cell would condense into chromosomes inside the somatic cell not in the ooplast and that the somatic cell would direct the chromosome alignment and initial spindle formation, which would then be normal. The nucleus of the somatic cell, at its second stage of division and correctly assembled, would then undergo chromosome segregation in the ooplast, resulting in twice its diploid nuclear content during in-vitro maturation. As a result of an artificia
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
44-0-536 772181
European Society for Human Reproduction and Embryology
1-Jul-2003


Page: 1 2

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: