Trif, which helps the body respond to viruses and bacteria. This was the first time that anyone had identified a signaling protein directly activated by signals the innate immune system sends when it recognizes both bacteria and viruses. And recently, Beutler discovered rare genetic mutations in a subset of people who come down with a kind of severe sepsis, an acute and often deadly disease.

A graduate of the University of California, San Diego, Beutler received his medical degree from the University of Chicago. He has been a professor at Scripps Research since 2000. Prior to that, he had been a Professor at The University of Texas Southwestern Medical Center at Dallas and an Assistant Professor at The Rockefeller University. He will receive his share of the total prize money of 65,000 Euros (about $83,000) in the presence of the German Federal Minister of Health and Social Safety later this year.

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Contact: Jason Bardi
jasonb@scripps.edu
858-784-9254
Scripps Research Institute
2-Apr-2004

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