HOME >> BIOLOGY >> NEWS
Scripps scientists discover rich medical drug resource in deep ocean sediments

Although the oceans cover 70 percent of the planet's surface, much of their biomedical potential has gone largely unexplored. Until now.

A group of researchers at Scripps Institution of Oceanography at the University of California, San Diego, have for the first time shown that sediments in the deep ocean are a significant biomedical resource for microbes that produce antibiotic molecules.

In a series of two papers, a group led by William Fenical, director of the Center for Marine Biotechnology and Biomedicine (CMBB) at Scripps Institution, has reported the discovery of a novel group of bacteria found to produce molecules with potential in the treatment of infectious diseases and cancer.

"The average person thinks of the bottom of the ocean as a dark, cold, and nasty place that is irrelevant, but we've shown that this environment may be a huge resource for new antibiotics and drugs for the treatment of cancer," said Fenical.

The first paper, published in the October, 2002 issue of Applied and Environmental Microbiology, highlights the discovery of new bacteria, called actinomycetes, from ocean sediments. For more than 45 years, terrestrial actinomycetes were the foundation of the pharmaceutical industry because of their ability to produce natural antibiotics, including important drugs such as streptomycin, actinomycin, and vancomycin. The data from this paper provide the first conclusive evidence of the widespread occurrence of indigenous actinomycete populations in marine sediments.

The second paper, published in the Jan. 20, 2003 issue of the international edition of the chemistry journal Angewandte Chemie, identifies the structure of a new natural product, which Fenical's group has named Salinosporamide A, from this new bacterial resource. The new compound is a potent inhibitor of cancer growth, including human colon carcinoma, non-small cell lung cancer, and, most effectively, breast cancer. January's report crack
'"/>

Contact: Mario Aguilera or Cindy Clark
scrippsnews@ucsd.edu
858-534-3624
University of California - San Diego
17-Jan-2003


Page: 1 2 3

Related biology news :

1. Structure solved at Scripps shows how one human protein reduces potency of chemotherapy
2. Protein believed to control formation of memory identified by Scripps & UCSD scientists
3. 22-amino acid bacterium created by Scripps scientists
4. Scripps scientists look deep inside sharks and their high-performance swimming system
5. Scripps research scientist wins 2004 Koch Prize
6. Scripps Research scientists find deafness genes function
7. New approach limits damage after heart attack and improves survival, say Scripps Research scientists
8. Scripps scientists describe dangerous cocktail of alcohol, brain peptides, and neurotransmitters
9. Chemical that turns mouse stem cells into heart muscles discovered by Scripps researchers
10. Structure solved by Scripps scientists shows one way that body controls gene expression
11. Scripps scientists say genetic mutation doesnt protect against HIV and plague

Post Your Comments:
(Date:6/30/2015)... June 30, 2015 Genisphere announced ... CEO to help further develop Genisphere,s therapeutics capabilities and ... experience, having spent much of the last 25 years ... Baxter Bioscience, and Johnson & Johnson. Tom started his ... and Biotech Corporate Finance. He graduated from Dartmouth College ...
(Date:6/25/2015)... -- According to a new market ... Technology, Material (Optical Prism, Piezoelectric, Capacitive & Adhesives), ... & Geography - Global Forecast to 2014 - ... expected to reach $14,500.07 Million by 2020, at ... 76 market Tables and 109 Figures spread through ...
(Date:6/24/2015)... YORK , June 24, 2015 The ... rate. The major drivers for the market include growth ... number of new drug launches. Over the years, the ... increased. Between 2001 and 2010, the FDA approved 225 ... according to WIPO, Europe accounted ...
Breaking Biology News(10 mins):Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4
(Date:7/1/2015)... 2015   Decision Resources Group finds ... Otezla are its oral administration, alternative mechanism of ... surveyed rheumatologists. Otezla was the first oral therapy ... active psoriatic arthritis in the United ... includes conventional oral treatments including disease-modifying antirheumatic drugs ...
(Date:7/1/2015)... and BANGALORE, India , July 1, ... company that uses next generation sequencing technology to empower ... A. Storrer as chief executive officer. In his ... be responsible for all strategy, business expansion and worldwide ... has served as Strand,s chairman and CEO since its ...
(Date:7/1/2015)... 1, 2015  Axovant Sciences Ltd. (NYSE:  AXON), ... treatment of dementia, today announced that the company ... at 5:45 p.m. EDT following its presentation of ... Conference 2015 (AAIC). The event ... Dr. Lawrence Friedhoff , Chief Development Officer, ...
(Date:7/1/2015)... ... July 01, 2015 , ... A newly launched business plan contest will ask ... to innovation in life sciences R&D. The Pistoia Alliance President’s Startup Challenge 2015 will ... and a period of expert mentorship from a senior industry figure drawn from the ...
Breaking Biology Technology:Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 2Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 3Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 2Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 3Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3Pistoia Alliance Launches Startup Challenge 2Pistoia Alliance Launches Startup Challenge 3
Cached News: