HOME >> BIOLOGY >> NEWS
Scripps scientists discover rich medical drug resource in deep ocean sediments

Although the oceans cover 70 percent of the planet's surface, much of their biomedical potential has gone largely unexplored. Until now.

A group of researchers at Scripps Institution of Oceanography at the University of California, San Diego, have for the first time shown that sediments in the deep ocean are a significant biomedical resource for microbes that produce antibiotic molecules.

In a series of two papers, a group led by William Fenical, director of the Center for Marine Biotechnology and Biomedicine (CMBB) at Scripps Institution, has reported the discovery of a novel group of bacteria found to produce molecules with potential in the treatment of infectious diseases and cancer.

"The average person thinks of the bottom of the ocean as a dark, cold, and nasty place that is irrelevant, but we've shown that this environment may be a huge resource for new antibiotics and drugs for the treatment of cancer," said Fenical.

The first paper, published in the October, 2002 issue of Applied and Environmental Microbiology, highlights the discovery of new bacteria, called actinomycetes, from ocean sediments. For more than 45 years, terrestrial actinomycetes were the foundation of the pharmaceutical industry because of their ability to produce natural antibiotics, including important drugs such as streptomycin, actinomycin, and vancomycin. The data from this paper provide the first conclusive evidence of the widespread occurrence of indigenous actinomycete populations in marine sediments.

The second paper, published in the Jan. 20, 2003 issue of the international edition of the chemistry journal Angewandte Chemie, identifies the structure of a new natural product, which Fenical's group has named Salinosporamide A, from this new bacterial resource. The new compound is a potent inhibitor of cancer growth, including human colon carcinoma, non-small cell lung cancer, and, most effectively, breast cancer. January's report crack
'"/>

Contact: Mario Aguilera or Cindy Clark
scrippsnews@ucsd.edu
858-534-3624
University of California - San Diego
17-Jan-2003


Page: 1 2 3

Related biology news :

1. Structure solved at Scripps shows how one human protein reduces potency of chemotherapy
2. Protein believed to control formation of memory identified by Scripps & UCSD scientists
3. 22-amino acid bacterium created by Scripps scientists
4. Scripps scientists look deep inside sharks and their high-performance swimming system
5. Scripps research scientist wins 2004 Koch Prize
6. Scripps Research scientists find deafness genes function
7. New approach limits damage after heart attack and improves survival, say Scripps Research scientists
8. Scripps scientists describe dangerous cocktail of alcohol, brain peptides, and neurotransmitters
9. Chemical that turns mouse stem cells into heart muscles discovered by Scripps researchers
10. Structure solved by Scripps scientists shows one way that body controls gene expression
11. Scripps scientists say genetic mutation doesnt protect against HIV and plague

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ITHACA, N.Y. , June 23, 2017  IBM ... in dairy research, today announced a new collaboration using ... the chances that the global milk supply is impacted ... project, Cornell University has become the newest academic institution ... Chain, a food safety initiative that includes IBM Research, ...
(Date:5/16/2017)... , May 16, 2017   Bridge ... health organizations, and MD EMR Systems , ... development partner for GE, have established a partnership ... Portal product and the GE Centricity™ products, including ... EMR. These new integrations will ...
(Date:4/18/2017)... SUNNYVALE, Calif. , April 18, 2017  Socionext Inc., a ... prototype of a media edge server, the M820, which features the ... face recognition software provided by Tera Probe, Inc., will be showcased ... and at the NAB show at the Las Vegas ... ...
Breaking Biology News(10 mins):
(Date:9/19/2017)... ... September 19, 2017 , ... Participants ... and a high-performance fume hood. Along with the advantages and disadvantages of ductless, ... vs. ducted hoods in the laboratory. , Attendees will learn from an industry ...
(Date:9/19/2017)... ... September 19, 2017 , ... The new and improved ... The pocket testers even stand upright with a new cap design that is versatile, ... in the field who need to test water quality. , The Oakton pocket testers ...
(Date:9/19/2017)... MI (PRWEB) , ... September 19, 2017 , ... ... laboratory, is pleased to announce the recipients of its 2017 Science Student Award. ... exceptional leadership qualities, and involvement with community service defray the costs of obtaining ...
(Date:9/19/2017)... ... September 19, 2017 , ... Band-LOK, LLC, an ... today that two new patents have been allowed by the USPTO on the ... said, “We continue to explore additional clinically-relevant designs for both the implants and ...
Breaking Biology Technology:
Cached News: