HOME >> BIOLOGY >> NEWS
Sea Grant researchers isolate new antibiotic from fish

Raleigh, N.C. North Carolina Sea Grant researchers are reporting the discovery of a new peptide antibiotic in fish that may have implications for treating diseases in both humans and animals, according to the November 15th issue of the peer-review journal, Nature.

Named piscidins after the Latin term "pisces" for fishes, the antibiotics were isolated from mast cells in hybrid striped bass. Mast cells are the most common tissue immune cell found in fish and other vertebrates, including humans. They are present in many tissues, including the skin, gills, and gastrointestinal tract. This is the first time that researchers have isolated a peptide antibiotic from mast cells of any animals, including humans. However, it is unclear whether fish mast cells are from the same lineage as mammal mast cells.

"The peptide antibiotics or piscidins have the potential to fight important bacterial pathogens of both fish and mammals, including multi-drug resistant bacteria," said Ed Noga, professor at the North Carolina State University College of Veterinary Medicine, and head of the research team that made the discovery.

"The antibiotics could be a useful template for designing new drugs because they are novel structures and not related to any known and currently used antibiotic," notes Noga. "With the development of antibiotic-resistant bacteria, there is an urgent need to find new types of antibiotics that can fight these resistant pathogens."

"While mast cells are one of the most common immune cells of vertebrates, their role as a critical line of defense has been uncertain," he added. "However, if any type of peptide antibiotic is also present in human mast cells, it could have important implications for treating human diseases, including asthma, skin allergies and certain types of arthritis, because of the prominent role that mast cells play in these diseases."

North Carolina Sea Grant Director Ron Hodson points out that the research
'"/>

Contact: Ed Noga
ed_noga@ncsu.edy
919-515-6236
National Sea Grant College Program
14-Nov-2001


Page: 1 2

Related biology news :

1. Grant advances biochemical engineering laboratory
2. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
3. Grant from GE Foundation to University of Houston to strengthen math, tech pipeline
4. McGill Centre for Intellectual Property Policy receives $3 million SSHRC Grant
5. Grant promotes marine ornamental fish aquaculture
6. Grant of powerful computer to Rutgers-Newark will increase understanding of brain activity
7. Grant renews funding of research toward cloning primates
8. Lipids get the spotlight in new NIGMS Glue Grant
9. Grant funds research to develop tissue-engineered solutions for heart disease
10. Grant strengthens research arm of Penn State Hershey Medical Centers ALS Clinic
11. Sea Grant News & Notes for March 26, 2003

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. Mohamed Anwar ... prestigious international IAIR Award for the most innovative high security ePassport and ... ... Maldives Immigration Controller General, Mr. Mohamed ... the right) have received the IAIR award for the "Most innovative high ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), ... published by MarketsandMarkets, the market is expected to be worth USD 18.98 billion ... Continue Reading ... ...      (Logo: ...
(Date:3/22/2017)... VILNIUS, Lithuania , March 21, 2017 /PRNewswire/ ... identification and object recognition technologies, today announced the ... development kit (SDK), which provides improved facial recognition ... safety cameras on a single computer. The new ... algorithms to improve accuracy, and it utilizes a ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... genomics analysis platform specifically designed for life science researchers to analyze and ... researcher Rosalind Franklin, who made a major contribution to the discovery of ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... announced today it will be hosting a Webinar titled, “Pathology is going digital. ... Associates , on digital pathology adoption best practices and how Proscia improves lab ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... has granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and ... of osteosarcoma. SBT-100 is able to cross the cell membrane and bind intracellular ...
(Date:10/10/2017)... International research firm Parks Associates announced today that Tom ... 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and ...
Breaking Biology Technology:
Cached News: