HOME >> BIOLOGY >> NEWS
Seattle Researchers Zero In On Location Of Gene For Inherited Prostate Cancer; Gene Also Linked To Brain Cancer

Significant research findings from Michael Milken's CaP CURE funding

SEATTLE - Scientists at the Fred Hutchinson Cancer Research Center and the University of Washington have mapped the region of a gene associated with prostate cancer that runs in families. The gene also may trigger an inherited susceptibility to primary brain cancer.

The study results appear in the American Journal of Human Genetics.

The researchers, who worked three and a half years to map the gene, have named it CAPB, short for "cancer of the prostate and brain." The gene is located on the short arm of chromosome 1 in a region called 1p36.

"Finding genes such as CAPB may provide clues that will eventually help diagnose, treat, cure and even prevent prostate cancer," says senior author Dr. Elaine Ostrander, head of the Genetics Program at the Hutchinson Center and a UW affiliate professor of molecular biotechnology and zoology.

Dr. Janet Stanford, an epidemiologist at the Hutchinson Center and at UW, oversaw recruitment of the 141 families nationwide involved in the Prostate Cancer Genetic Study, or PROGRESS.

"None of this work would have been possible without the participation of these families," says Stanford, a member of the Hutchinson Center's Division of Public Health Sciences and UW research professor of epidemiology. Families enrolled in PROGRESS included those with three or more first-degree relatives with prostate cancer, three or more generations affected by prostate cancer and/or two first-degree relatives diagnosed with prostate cancer by age 60.

Participants included men with and without prostate cancer and selected women, all of whom were asked to fill out questionnaires and donate blood samples for DNA analysis.

Of each family that participated, blood samples were taken from an average of three to four men with prostate cancer. At least a dozen of the families had confirmed cases of both prostate and primary brain cancers. Several pr
'"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
11-Mar-1999


Page: 1 2 3

Related biology news :

1. Agronomy, crop, and soil science societies to meet Oct. 31 to Nov. 4 in Seattle
2. Sleepless over Seattle: Migrating songbirds forgo sleep but keep their wits
3. Seattle, New York researchers to receive neuroscience prize endowed by UNC scientist
4. Worlds largest scientific society convenes regional meeting June 14-17 in Seattle
5. Five Seattle scientists selected as Howard Hughes Medical Institute investigators
6. Trade, science, risk, precaution: Issues for Seattle
7. Researchers determine genetic cause of Timothy syndrome
8. Researchers find color sensitive atomic switch in bacteria
9. Researchers identify protein promoting vascular tumor growth
10. Researchers devise potent new tools to curb ivory poaching
11. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/3/2017)... , April 3, 2017  Data captured ... engineering platform, detected a statistically significant association ... prior to treatment and objective response of ... potential to predict whether cancer patients will ... treatment, as well as to improve both pre-infusion ...
(Date:3/30/2017)... 2017 The research team of The Hong ... fingerprint identification by adopting ground breaking 3D fingerprint minutiae recovery and ... speed and accuracy for use in identification, crime investigation, immigration control, ... ... A research team led ...
(Date:3/29/2017)... CHICAGO , March 29, 2017  higi, the ... ecosystem in North America , today ... Partners and the acquisition of EveryMove. The new investment ... extensive set of tools to transform population health activities ... and lifestyle data. higi collects and secures ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that give it ... Nanoparticle), a technology developed in collaboration with Children’s Hospital Los Angeles (CHLA). ...
(Date:10/10/2017)... SANTA CRUZ, Calif. , Oct. 10, 2017 /PRNewswire/ ... SBIR grant from the NIH to develop RealSeq®-SC (Single ... preparation kit for profiling small RNAs (including microRNAs) from ... Cell Analysis Program highlights the need to accelerate development ... "New techniques for ...
(Date:10/9/2017)... Jupiter, FL (PRWEB) , ... October 09, 2017 , ... ... episode, scheduled to broadcast first quarter 2018. American Farmer airs Tuesdays at 8:30aET on ... Agriculture industry is faced with the challenge of how to continue to feed a ...
(Date:10/7/2017)... ... October 06, 2017 , ... With ... microscopy and surface analysis, Nanoscience Instruments is now expanding into Analytical Services. ... range of contract analysis services for advanced applications. Services will leverage techniques ...
Breaking Biology Technology:
Cached News: