Seeing How the Brain Changes During Aging

oup has also developed a radiotracer that monitors the level of an enzyme called MAO B that breaks down dopamine. Levels of MAO B increase as we age, contributing to dopamine deficiency. A drug called L-Deprenyl inhibits MAO B and is used to treat patients with Parkinson's and Alzheimer's disease. Fowler says that the PET studies suggest that if we can do things to enhance the activity of dopamine in the human brain, we may be able to slow down some of the cognitive and motor declines in aging and might be able to help determine what doses of the drug would be most beneficial to an individual.

Paper ORGN 4 will be presented by J. S. Fowler from 11:00 a.m. to 12:00 noon, Sun., March 29, in the Convention Center Ballroom A I, Level 3.

A nonprofit organization with a membership of more than 155,000 chemists and chemical engineers, the American Chemical Society publishes scientific journals, convenes major research conferences, and provides educational, science policy and career programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Ohio.


Contact: Nancy Blount
American Chemical Society

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