HOME >> BIOLOGY >> NEWS
Sensor uses DNA to detect presence of lead, a dangerous contaminant

CHAMPAIGN, Ill. Lead is a common environmental contaminant that can cause a number of health problems, particularly in children. Current techniques for lead detection require sophisticated equipment or complicated sample treatment. Now, researchers at the University of Illinois have developed a simple and inexpensive method that permits real-time, on-site detection of lead ions.

A unique feature of our lead sensors is that they consist of small pieces of DNA, the same basic building block of our genes, said Yi Lu, a UI professor of chemistry. DNA is a well-known genetic material with different combinations of code or sequences that determine individual characteristics such as eye color, hair color and height.

This represents a new class of simple and environmentally safe sensors and is the first example of a catalytic DNA-based biosensor for metal ions, Lu said. It combines the high metal ion selectivity of catalytic DNA with the high sensitivity of fluorescence detection.

Because DNA is stable, cost-effective and easily adaptable to optical fiber and chip technology, the catalytic DNA system is an ideal candidate for real-time, remote sensing of lead in applications such as environmental monitoring, clinical toxicology and industrial process monitoring.

To search for the unique sequence of DNA that could distinguish lead from other metal ions, Lu and graduate student Jing Li used a method called in vitro selection. The selection process is capable of sampling a very large pool of DNA sequences (up to 1000 trillion molecules), amplifying the desired sequences by the polymerase chain reaction and introducing mutations to improve performance.

Using in vitro selection, Lu and Li found several DNA sequences that were especially responsive to the presence of lead ions. To enhance the sensitivity of the sensor, the researchers attached a fluorescent tag to a specific DNA sequence.

While most DNA is double stranded, the catalytic DNA Lu and Li
'"/>

Contact: James E. Kloeppel, Physical Sciences Editor
kloeppel@uiuc.edu
217-244-1073
University of Illinois at Urbana-Champaign
2-Nov-2000


Page: 1 2

Related biology news :

1. Sensors at Watts Bar being evaluated by ORNL
2. SensorNet proposed as system to protect millions nationwide
3. Sensor Networks
4. New Carbon Monoxide Sensor Developed For Occupational Use
5. Microchip Sensor Detects Bacteria
6. Getting At The Components Of Mechanotransduction: Genes Required For Vertebrate Sensory Hair Cell Function Identified
7. New Sensor Will Detech Chemical And Biological Pathogens At Incredibly Small Doses
8. New Sensor Adds Precision To Search For Dangerous Gases
9. A Sensor, A Switch, A Zipper: Protein Engineers Design Potential Tool
10. New Sensor Provides First Instant Test For Toxic E. coli Organism
11. New sequence involved in DNA replication timing may aid in cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sensor uses DNA detect presence lead dangerous contaminant

(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... of the "Global Wearable Technologies Market and ... Overview, Trends and Forecast 2014-2020" report to ... are smart devices that can be worn on ...
(Date:1/22/2015)... CHARLOTTE, N.C. , Jan. 22, 2015 Infinisource has ... introduction of the G2 model. The G2 sets a higher ... company,s iSolved human capital management solution. With plug-and-play installation, touch ... G2 time clock provides a robust time collection solution for ...
(Date:12/22/2014)... 2014  NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... the growing mobile commerce market, announces it has retained famous ... the 2015 International CES debut of the Wocket™ biometric smart ... at the NXT-ID booth January 6th and 7 th , ...
Breaking Biology News(10 mins):Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2Infinisource's NXG series sets new time clock standard 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4
(Date:1/23/2015)... Portal Solutions , a technology consulting ... Microsoft Office 365 and SharePoint platforms , today announces its ... being one of the region’s fastest-growing mid-sized companies based on ... , “To be recognized a second year in a row ...
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)... NH (PRWEB) January 22, 2015 GEA ... a table top laboratory homogenizer, the PandaPLUS 2000, which ... nanodispersions, nanoemulsions , and cell disruption . This ... dairy products, fruit juices, liquid food, food additives and ...
(Date:1/22/2015)... Mass (PRWEB) January 21, 2015 Cambridge Semantics, ... Web technology, today announced that 2014 was a record-breaking year ... the capabilities of the Anzo Smart Data Platform and our ... and utilize insights from diverse data which led to record ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Cambridge Semantics Announces Record Results for 2014 2
Cached News: