HOME >> BIOLOGY >> NEWS
Severe depression associated with greater number of nerve cells in thalamus region of brain

Individuals who suffer from severe depression have more nerve cells in the part of the brain that controls emotion, researchers at UT Southwestern Medical Center at Dallas have found.

Studies of postmortem brains of patients diagnosed with major depressive disorder (MDD) showed a 31 percent greater than average number of nerve cells in the portion of the thalamus involved with emotional regulation. Researchers also discovered that this portion of the thalamus is physically larger than normal in people with MDD. Located in the center of the brain, the thalamus is involved with many different brain functions, including relaying information from other parts of the brain to the cerebral cortex.

The findings, published in today's issue of The American Journal of Psychiatry, are the first to directly link a psychiatric disorder with an increase in total regional nerve cells, said Dr. Dwight German, professor of psychiatry at UT Southwestern.

"This supports the hypothesis that structural abnormalities in the brain are responsible for depression," he said. "Often people don't understand why mentally ill people behave in odd ways. They may think they have a weak will or were brought up in some unusual way.

"But if their brains are different, they're going to behave differently. Depression is an emotional disorder. So it makes sense that the part of the brain that is involved in emotional regulation is physically different."

Four groups were represented in the study: subjects with major depression, with bipolar disorder and with schizophrenia, as well as a comparison group with no history of mental illness. Major depression is characterized by a depressed mood and lack of interest or pleasure in normal activities for a prolonged period of time, while bipolar disease is distinguished by alternating periods of extreme mania or elevated mood swings, and severe depression. Schizophrenia often results in psychotic episodes of hallucinations
'"/>

Contact: Donna Steph Hansard
donna.hansard@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
1-Jul-2004


Page: 1 2

Related biology news :

1. Severe kidney disease in blacks linked to genes on two chromosomes
2. Severe Pain Following Shingles Safely Relieved In Clinical Trial Of Anti-Convulsant Drug Gabapentin
3. Scientists Find Gene For Severe Form Of Epilepsy
4. Severe Falciparum Malaria Increases In Honduras
5. Common Anti-Viral Medication Prevents Severe Eye Herpes
6. Common Food Dye Can Cause Severe Allergic Reactions
7. Oral Vaccine Protects Infants From Severe Rotavirus Diarrhea
8. Alcohol-use and depression among pregnant and postpartum women
9. Scientists build on case connecting inflammatory disease and depression
10. UT Southwestern researchers study benefit of exercise, medication on depression
11. Common treatment for depression is safe and effective for Alzheimers patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... First quarter 2016:   , ... the first quarter of 2015 The gross margin was ... 18.8) and the operating margin was 40% (-13) Earnings ... flow from operations was SEK 249.9 M (21.2) , ... SEK 7,000-8,500 M. The operating margin for 2016 is ...
(Date:4/19/2016)... -- The new GEZE SecuLogic access control ... system solution for all door components. It can be ... interface with integration authorization management system, and thus fulfills ... dimensions of the access control and the optimum integration ... considerable freedom of design with regard to the doors. ...
(Date:4/14/2016)... April 14, 2016 BioCatch ... Detection, today announced the appointment of Eyal Goldwerger ... role. Goldwerger,s leadership appointment comes at a ... of the deployment of its platform at several of ... technology, which discerns unique cognitive and physiological factors, is ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... Boston, MA (PRWEB) , ... April 28, 2016 ... ... (EDT), Asymmetrex will deliver a talk on its first-in-class technologies for ... the 2016 Meeting on RNAiMicroRNA Biology to Reprogramming & CRISPR-based Genome ...
(Date:4/27/2016)... ... ... The Pittcon Organizing Committee is pleased to announce that Charles “Chuck” Gardner ... Committee since 1987. Since then, he has served in a number of key leadership ... both the program and exposition committees. In his professional career, Dr. Gardner is the ...
(Date:4/27/2016)... (PRWEB) , ... April 27, 2016 , ... ... that Jon Clark has joined the company as an Expert Consultant. Mr. ... for industry collaborations and managing the development of small molecule monographs based on ...
(Date:4/27/2016)... MedDay, a biotechnology company focused on ... of Catherine Moukheibir as Chairman of its Board of Directors. ... Jacques Garaud , who contributed to the rapid development of ... Catherine started her career in strategy consulting and investment ... London .  She held C-Suite level roles in some ...
Breaking Biology Technology:
Cached News: