HOME >> BIOLOGY >> NEWS
Severe depression associated with greater number of nerve cells in thalamus region of brain

Individuals who suffer from severe depression have more nerve cells in the part of the brain that controls emotion, researchers at UT Southwestern Medical Center at Dallas have found.

Studies of postmortem brains of patients diagnosed with major depressive disorder (MDD) showed a 31 percent greater than average number of nerve cells in the portion of the thalamus involved with emotional regulation. Researchers also discovered that this portion of the thalamus is physically larger than normal in people with MDD. Located in the center of the brain, the thalamus is involved with many different brain functions, including relaying information from other parts of the brain to the cerebral cortex.

The findings, published in today's issue of The American Journal of Psychiatry, are the first to directly link a psychiatric disorder with an increase in total regional nerve cells, said Dr. Dwight German, professor of psychiatry at UT Southwestern.

"This supports the hypothesis that structural abnormalities in the brain are responsible for depression," he said. "Often people don't understand why mentally ill people behave in odd ways. They may think they have a weak will or were brought up in some unusual way.

"But if their brains are different, they're going to behave differently. Depression is an emotional disorder. So it makes sense that the part of the brain that is involved in emotional regulation is physically different."

Four groups were represented in the study: subjects with major depression, with bipolar disorder and with schizophrenia, as well as a comparison group with no history of mental illness. Major depression is characterized by a depressed mood and lack of interest or pleasure in normal activities for a prolonged period of time, while bipolar disease is distinguished by alternating periods of extreme mania or elevated mood swings, and severe depression. Schizophrenia often results in psychotic episodes of hallucinations
'"/>

Contact: Donna Steph Hansard
donna.hansard@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
1-Jul-2004


Page: 1 2

Related biology news :

1. Severe kidney disease in blacks linked to genes on two chromosomes
2. Severe Pain Following Shingles Safely Relieved In Clinical Trial Of Anti-Convulsant Drug Gabapentin
3. Scientists Find Gene For Severe Form Of Epilepsy
4. Severe Falciparum Malaria Increases In Honduras
5. Common Anti-Viral Medication Prevents Severe Eye Herpes
6. Common Food Dye Can Cause Severe Allergic Reactions
7. Oral Vaccine Protects Infants From Severe Rotavirus Diarrhea
8. Alcohol-use and depression among pregnant and postpartum women
9. Scientists build on case connecting inflammatory disease and depression
10. UT Southwestern researchers study benefit of exercise, medication on depression
11. Common treatment for depression is safe and effective for Alzheimers patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2019)... ... 16, 2019 , ... At nearly eleven years old, Seve, a white Golden ... owner, in the last year or so, he was a little “gimpy” and occasionally ... Echevarria of VCA University Animal Hospital in Dallas, diagnosed him with severe ...
(Date:7/9/2019)... , ... July 09, 2019 , ... ... Tx Genetic Research into its incubator program. The founder and CEO of Tx ... improve the lives of those suffering from epithelial connective tissue disorders. , “We ...
(Date:6/27/2019)... ... June 27, 2019 , ... Lighting designers from integrated design firm ... which honored the designers for creating both engaging and energy efficient lighting systems. , ... an office tower in San Diego, California earned an IES Illumination Award of Merit ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... NEWPORT BEACH, Calif. (PRWEB) , ... May 30, ... ... the future of neurotoxins, is pleased to announce the strategic acquisition of Metabiologics, ... for research. The acquisition provides Object exclusive ownership and commercialization rights to a ...
(Date:5/15/2019)... ... May 15, 2019 , ... Milton Hershey School® has named William ... work within the biomedical industry, where he is changing lives by creating solutions to ... “William Harding epitomizes the vision of our founders – Milton and Catherine Hershey – ...
(Date:5/8/2019)... ... 2019 , ... Standing at 16.2 hands, Atlas is on the large side for a Quarter ... barrel racing, among other activities. When loping around a corner in late 2017, Atlas ... busy horse to only being able to walk. Fortunately Atlas’ owner, Kelly, sought the ...
(Date:5/2/2019)... ... April 30, 2019 , ... ... standard, REPROCELL USA Inc. has demonstrated its ability to provide various services ... aims to enhance customer satisfaction through the effective implementation of its quality ...
Breaking Biology Technology:
Cached News: