HOME >> BIOLOGY >> NEWS
Severe depression associated with greater number of nerve cells in thalamus region of brain

Individuals who suffer from severe depression have more nerve cells in the part of the brain that controls emotion, researchers at UT Southwestern Medical Center at Dallas have found.

Studies of postmortem brains of patients diagnosed with major depressive disorder (MDD) showed a 31 percent greater than average number of nerve cells in the portion of the thalamus involved with emotional regulation. Researchers also discovered that this portion of the thalamus is physically larger than normal in people with MDD. Located in the center of the brain, the thalamus is involved with many different brain functions, including relaying information from other parts of the brain to the cerebral cortex.

The findings, published in today's issue of The American Journal of Psychiatry, are the first to directly link a psychiatric disorder with an increase in total regional nerve cells, said Dr. Dwight German, professor of psychiatry at UT Southwestern.

"This supports the hypothesis that structural abnormalities in the brain are responsible for depression," he said. "Often people don't understand why mentally ill people behave in odd ways. They may think they have a weak will or were brought up in some unusual way.

"But if their brains are different, they're going to behave differently. Depression is an emotional disorder. So it makes sense that the part of the brain that is involved in emotional regulation is physically different."

Four groups were represented in the study: subjects with major depression, with bipolar disorder and with schizophrenia, as well as a comparison group with no history of mental illness. Major depression is characterized by a depressed mood and lack of interest or pleasure in normal activities for a prolonged period of time, while bipolar disease is distinguished by alternating periods of extreme mania or elevated mood swings, and severe depression. Schizophrenia often results in psychotic episodes of hallucinations
'"/>

Contact: Donna Steph Hansard
donna.hansard@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
1-Jul-2004


Page: 1 2

Related biology news :

1. Severe kidney disease in blacks linked to genes on two chromosomes
2. Severe Pain Following Shingles Safely Relieved In Clinical Trial Of Anti-Convulsant Drug Gabapentin
3. Scientists Find Gene For Severe Form Of Epilepsy
4. Severe Falciparum Malaria Increases In Honduras
5. Common Anti-Viral Medication Prevents Severe Eye Herpes
6. Common Food Dye Can Cause Severe Allergic Reactions
7. Oral Vaccine Protects Infants From Severe Rotavirus Diarrhea
8. Alcohol-use and depression among pregnant and postpartum women
9. Scientists build on case connecting inflammatory disease and depression
10. UT Southwestern researchers study benefit of exercise, medication on depression
11. Common treatment for depression is safe and effective for Alzheimers patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... August 13, 2019 , ... Join Anguraj Sadanandam, ... Institute of Cancer Research (ICR) in a live webinar on Wednesday, ... of biomarker and companion diagnostic development including machine learning approaches in different gastrointestinal ...
(Date:8/9/2019)... ARLINGTON, Va. (PRWEB) , ... August 09, 2019 , ... ... options for patients, more and more patients will visit urgent care centers (UCC) in ... firm Kalorama Information. The report, The Market for Urgent Care Centers , is ...
(Date:8/6/2019)... ... August 06, 2019 , ... VetStem ... clinical, regulatory and GMP manufacturing experience. In November it spun out a ... extensive regulatory experience and one of the first cGMP cell manufacturing facilities ...
Breaking Biology News(10 mins):
(Date:8/14/2019)... Pa. (PRWEB) , ... August 13, 2019 , ... ... nuclear receptor and in vitro toxicology testing solutions, announced the appointment of Mark ... industry experience to the Board. , Mark McLoughlin will lend his healthcare expertise ...
(Date:8/7/2019)... ... ... Locus Agricultural Solutions (Locus AG) reports record levels of carbon sequestered in ... ® , which is pulling up to 121% more carbon into the soil than ... from the treatment of almonds, cherries, turf/sod, grapes and citrus across the U.S., as ...
(Date:8/6/2019)... DEERFIELD, Ill. (PRWEB) , ... August 05, 2019 ... ... announced that Jason Casarella has been recognized as a distinguished leader by PharmaVOICE ... is featured in an article in the magazine’s July/August special issue. , As ...
(Date:7/30/2019)... , ... July 30, 2019 , ... ... premiere team building and cooking events company. Not only has the company already ... also started offering Private Cooking Parties to its guests. , With Lajollacooks4u’s Private ...
Breaking Biology Technology:
Cached News: