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Sex Differences in Cardiovascular Disease

of Alabama at Birmingham - Research shows premenopausal women have lower blood pressure than men of the same age, but that postmenopausal women have higher blood pressure than their male counterparts. These findings suggest that ovarian hormones may affect blood pressure levels. Oparil talked about her work in this area and the cardiovascular effects of estrogen.

  • Richard E. White, Ph.D., an associate professor of pharmacology and toxicology at the Medical College of Georgia in Augusta - Sex steroids, such as estrogen, progesterone and testosterone, have been found to relax coronary artery smooth muscle. White discussed his work in this area and how this may explain some beneficial cardiovascular effects of these hormones.

  • Steven N. Ebert, Ph.D., an assistant professor of pharmacology at Georgetown University Medical Center in Washington, D.C. - Torsades de Pointes, a potentially fatal irregular heartbeat, is more common in women than men. The condition can arise due to congenital birth defects or be triggered by the use of certain medications. Ebert explained his animal studies investigating the biological basis for sex differences in Torsades de Pointes and his hypothesis on testosterone's protective role.

    Other presentations focused on cholesterol trafficking; recent cardiovascular clinical trials focusing on women and areas needing more research; sex differences in heart failure in older adults; and the effects of exercise on hypertrophic cardiomyopathy, a severe genetic heart disease that is the leading cause of sudden death in young athletes and is more common in women than men. Sue Ann Thompson, president of the Wisconsin Women's Health Foundation, opened the meeting as a special guest speaker.

    The scientific meeting was held as a satellite symposium of the International Society for Heart Research's annual meeting. The Society is sponsoring regional Scientific Advisory Meetings in response to the April
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    • Contact: Amy Hoskins
    amy@womens-health.org
    202-496-5015
    Society for Women's Health Research
    16-Jun-2003


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    		TAG: Sex Differences Cardiovascular Disease

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