HOME >> BIOLOGY >> NEWS
Skin condition linked to genetics in Caucasian and Chinese populations

A study at the University of Sheffield in the UK was conducted on the skin condition called psoriasis, revealing a link between susceptibility to psoriasis and regions on chromosomes 6p21 and 4q28-q31. According to the study, psoriasis, a chronic inflammatory dermatosis, is believed to be inherited and triggered by environmental, as well as genetic, factors. It affects "2%-5% of the Caucasian population and 0.1%-0.3% in the far East and China."

This new connection suggests that genes in Caucasians and this specific Chinese population may be involved in the origin and development of psoriasis. As the first meta-analysis performed in the area of this disease, the data collected confirms previous studies and spotlights two regions on chromosomes 6 (major histocompatibility complex MHC) and 4. Conclusively, the 4q28-q31 region has been identified as a focus for future investigation.

Over the past few years, ten genome-wide scans have been conducted, classifying 19 candidate regions for psoriasis. Of these regions, locus PSORS1 (within the MHC) has shown a large presence in the study results, encompassing data from six of the ten scans previously mentioned.

This study is published in the Journal of Investigative Dermatology. Media wishing to receive a pdf of this article please contact medicalnews@bos.blackwellpublishing.net.

About the Author
In 2001, Mr. Gurdeep Sagoo joined Dr. Tazi-Ahnini's group in the Division of Genomic Medicine at the University of Sheffield in the United Kingdom. The group has several other papers presented and published in the areas of psoriasis and dermatology. Mr. Sagoo and Dr. Tazi-Ahnini are both available for questions and interviews and can be reached at g.sagoo@sheffield.ac.uk or r.taziahnini@sheffield.ac.uk.


'"/>

Contact: Sharon Agsalda
medicalnews@bos.blackwellpublishing.net
781-388-8507
Blackwell Publishing Ltd.
15-Jul-2004


Page: 1

Related biology news :

1. Study yields insights into precancerous condition
2. Lack of immune system protein prevents lupus-like condition in mice
3. All ecosystems are equally productive under drought conditions
4. Model shows long-held constant in ocean nutrient ratio may vary as ecological conditions change
5. Study predicts conditions for sustainable lion trophy hunting
6. Chemists at four pharmaceutical companies named Heroes for treating childhood conditions
7. Researchers identify protein which could help protect against neuro-degenerative conditions
8. New cause identified for incurable muscle condition
9. Same gene found to cause mental retardation in children, neurodegenerative condition in older males
10. Facing extreme ice conditions, coast guard, NSF deploy second icebreaker to Antarctica
11. Some people of African descent more susceptible to heart condition, Science study suggests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... ... 2019 , ... Cambridge Innovation Institute (CII) is pleased to ... which includes four annual Internet of Business (IoB) events in the U.S., consisting ... Kuhl, President, Cambridge Innovation Institute, says, "We are delighted to be able to ...
(Date:2/11/2019)... (PRWEB) , ... February 11, 2019 , ... ... DNA analysis products and services, announced a new forensic genealogy service offering to ... combines advanced DNA testing and genealogy to develop ancestral relationships between samples ...
(Date:2/2/2019)... ... January 31, 2019 , ... ... genomics, has awarded microbiome research support in study design, planning, sample collection, and ... Professor of Obstetrics and Gynecology, and Dr. Sara Vaughn, MD, Reproductive Endocrinology and ...
Breaking Biology News(10 mins):
(Date:1/24/2019)... ... January 22, 2019 , ... Controlled Contamination Services is ... in the US. Each of these valuable new team members will support its growing ... model moving forward as CCS scales its business. This addition will enable CCS to ...
(Date:1/24/2019)... ... January 22, 2019 , ... ... has its own set of assumptions, and RFP creation and management generally requires ... is like comparing apples to oranges. These challenges can ultimately lead to study ...
(Date:1/21/2019)... ... 2019 , ... Microbial Discovery Group (MDG), a leading Bacillus ... cleaning market. MDG’s SporActiv liquid and powder product line contains safe ingredients that ... floor and tile cleaners, carpets, drains, portable restroom cleaning and more. , ...
(Date:1/20/2019)... ... January 17, 2019 , ... Consumers are directing healthcare ... of physicians. That's changing as many services now exist for patients to order ... market totaled $208 million in 2018, according to Kalorama Information’s new report, ...
Breaking Biology Technology:
Cached News: