HOME >> BIOLOGY >> NEWS
St. Jude ranked among top 500 supercomputer centers

collection to discovery of important new findings."

"The Hartwell Center is dedicated to research that will benefit children, and in the long run, the research will benefit all people who suffer from some of the same catastrophic diseases that threaten children around the world," Naeve said. "In that sense, although this is a St. Jude resource, it will produce knowledge that will be a resource for the entire world."

"Our goal is to help St. Jude use information technology to quicken the pace of clinical research into children's diseases," said James Coffin, Ph.D., vice president, IBM Life Sciences. "The selection of the right technology was very important to St. Jude because of the complexity of the projects and the volume of data that researchers are dealing with in their investigations. We are very pleased that they chose IBM's BladeCenter for their computing needs."

One of the St. Jude projects uses the new computing power to study the motion of enzyme molecules in order to determine how these proteins work, and how mutations in them change or destroy their ability to do their jobs, Naeve said. Enzymes are large proteins that control the speed of specific biochemical reactions in the body. Many diseases are caused by malfunctioning enzymes.

"Shape is everything to a protein," Naeve said. "Mutations that change a protein's shape can derail the protein's function and disrupt the normal function of the cell. And the shape of a potential drug molecule determines whether it will interact properly with its target in the body."

A second project that has benefited from the supercomputer is the study of the flexibility of a tumor suppressor protein called p27, and how the flexibility affects the protein's function. The supercomputer cut computation time from 200 hours to just 20. Another project that is benefiting from the supercomputer is a study that screens various molecules to determine if they might be effective drugs agai
'"/>

Contact: Bonnie Cameron
bonnie.cameron@stjude.org
901-495-4815
St. Jude Children's Research Hospital
22-Dec-2003


Page: 1 2 3

Related biology news :

1. Cleaner water, more efficient electricity among UH chemical research
2. Alcohol-use and depression among pregnant and postpartum women
3. Parents are top influence on soft-drink consumption among kids
4. University of Pittsburgh medical center among first to implant heart assist device
5. Professor and student among tops in technology at UH
6. UCSD study shows how we perceive world depends on precise division of labor among cells in brain
7. Chronic respiratory symptoms prevalent among Alaska natives
8. Specifying alcohol-related brain-damage among heavy social drinkers
9. Researchers identify unifying code among diverse classes of natural antibiotics
10. Marsupial among model organisms next in line for sequencing
11. Mastectomy dramatically reduces breast cancer risk among women with BRCA1/2 mutations

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... April 11, 2017 No two people ... at the New York University Tandon School of ... have found that partial similarities between prints are ... in mobile phones and other electronic devices can ... The vulnerability lies in the fact that fingerprint-based ...
(Date:4/5/2017)... 2017 KEY FINDINGS The global ... a CAGR of 25.76% during the forecast period of ... factor for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is ... geography. The stem cell market of the product is ...
(Date:3/30/2017)... March 30, 2017 Trends, opportunities and forecast ... behavioral), by technology (fingerprint, AFIS, iris recognition, facial recognition, ... others), by end use industry (government and law enforcement, ... and banking, and others), and by region ( ... Asia Pacific , and the Rest ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Vilnius, Lithuania, announced today that they have entered into a multiyear collaboration to ... provide CRISPR researchers with additional tools for gene editing across all applications. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... BioMedGPS announces expanded coverage ... its newest module, US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats ... sealants, synthetic sealants and biologic sealants used in surgical applications. BioMedGPS estimates the ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... genomics analysis platform specifically designed for life science researchers to analyze and ... researcher Rosalind Franklin, who made a major contribution to the discovery of ...
(Date:10/11/2017)... YORBA LINDA, CA (PRWEB) , ... October 11, ... ... adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and ... activation (CRISPRa) system with small RNA guides is transformative for performing systematic gain-of-function ...
Breaking Biology Technology:
Cached News: