HOME >> BIOLOGY >> NEWS
St. Jude ranked among top 500 supercomputer centers

collection to discovery of important new findings."

"The Hartwell Center is dedicated to research that will benefit children, and in the long run, the research will benefit all people who suffer from some of the same catastrophic diseases that threaten children around the world," Naeve said. "In that sense, although this is a St. Jude resource, it will produce knowledge that will be a resource for the entire world."

"Our goal is to help St. Jude use information technology to quicken the pace of clinical research into children's diseases," said James Coffin, Ph.D., vice president, IBM Life Sciences. "The selection of the right technology was very important to St. Jude because of the complexity of the projects and the volume of data that researchers are dealing with in their investigations. We are very pleased that they chose IBM's BladeCenter for their computing needs."

One of the St. Jude projects uses the new computing power to study the motion of enzyme molecules in order to determine how these proteins work, and how mutations in them change or destroy their ability to do their jobs, Naeve said. Enzymes are large proteins that control the speed of specific biochemical reactions in the body. Many diseases are caused by malfunctioning enzymes.

"Shape is everything to a protein," Naeve said. "Mutations that change a protein's shape can derail the protein's function and disrupt the normal function of the cell. And the shape of a potential drug molecule determines whether it will interact properly with its target in the body."

A second project that has benefited from the supercomputer is the study of the flexibility of a tumor suppressor protein called p27, and how the flexibility affects the protein's function. The supercomputer cut computation time from 200 hours to just 20. Another project that is benefiting from the supercomputer is a study that screens various molecules to determine if they might be effective drugs agai
'"/>

Contact: Bonnie Cameron
bonnie.cameron@stjude.org
901-495-4815
St. Jude Children's Research Hospital
22-Dec-2003


Page: 1 2 3

Related biology news :

1. Cleaner water, more efficient electricity among UH chemical research
2. Alcohol-use and depression among pregnant and postpartum women
3. Parents are top influence on soft-drink consumption among kids
4. University of Pittsburgh medical center among first to implant heart assist device
5. Professor and student among tops in technology at UH
6. UCSD study shows how we perceive world depends on precise division of labor among cells in brain
7. Chronic respiratory symptoms prevalent among Alaska natives
8. Specifying alcohol-related brain-damage among heavy social drinkers
9. Researchers identify unifying code among diverse classes of natural antibiotics
10. Marsupial among model organisms next in line for sequencing
11. Mastectomy dramatically reduces breast cancer risk among women with BRCA1/2 mutations

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Jude ranked among top supercomputer centers

(Date:3/23/2015)... 2015  In the 2014 fiscal year, irs.gov recorded ... This figure accounts for a fraction of the estimated ... Report, exceeds $11 billion globally. The polygraph has traditionally ... has occurred. Investor Mark Saint Juste along ... Paolella partnered to administer the test in a ...
(Date:3/20/2015)... 19, 2015 Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ... - Global Strategic Business Report" report to their offering. ... Geometry in US$ Thousands. The report provides separate comprehensive analytics ... Japan , Europe , ... Rest of World. Annual estimates and forecasts are ...
(Date:3/19/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... mobile commerce market, announces its biometric payment technology, the Wocket® ... this week on Washington DC,s Fox ... segment "The Next Great Thing", host Laura Evans ... and ,a really big breakthrough in mobile payment.,  ...
Breaking Biology News(10 mins):Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
(Date:4/23/2015)... PA (PRWEB) April 23, 2015 ... it is the first EMC® Enterprise Content Division ... the entire EMC Documentum® for Life Sciences ... has proven knowledge and capabilities to provide life ... purpose-built solutions. , The EMC Documentum Solution ...
(Date:4/23/2015)... 23, 2015  Propanc Health Group Corporation (OTCBB: ... on the development of cancer treatments for patients ... product includes PRP, a patented formulation consisting of ... well as the enzyme amylase designed to synergistically ... combination of anti-cancer agents working in combination with ...
(Date:4/23/2015)... Delpor, Inc. (Delpor), a biotechnology company ... States Patent and Trademark Office has issued 2 new ... US Pat. No. 8,986,727 was issued on March ... device for the sustained release of therapeutic agents. ... sustained (zero-order) release of large and small molecules for ...
(Date:4/22/2015)... , April 22, 2015 /PRNewswire/ - BioAmber Inc. (NYSE and EURONEXT Paris:BIOA) today ... first quarter 2015 on Thursday, May 7, 2015 after ... a webcast and conference call for 4.30 pm ET ... Live audio of the conference call will be ... investors, members of the news media and the general ...
Breaking Biology Technology:Glemser Earns Accreditation for Life Sciences Solution Suite 2Early Stage BioTech offers Plenty of Risk; Propanc Health Group Analyst Brief Issued by BrokerBank Securities, Inc. 2Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 2Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 3BioAmber Announces Webcast of Fiscal First Quarter 2015 Financial Results 2
Cached News: