HOME >> BIOLOGY >> NEWS
Stanford explores new avenue for brain injury, paralysis research

STANFORD, Calif. - The central nervous system, made up of the brain and spinal cord, never forgets a slight. Somehow, nerve cells lose the ability to regenerate: witness actor Christopher Reeve's paralysis after his horse threw him at a jump. To find a cure for such injuries, scientists must understand why nerve cells lose the ability to grow back. They know that these cells - called neurons - stop regenerating because a signal tells them to slow down during development. The problem is, scientists haven't known much about that signal.

Now, a team of Stanford University Medical Center researchers have identified the mechanism and some key cells involved in controlling regeneration. It turns out that the signal to slow down doesn't come from the neurons themselves, but from an outside source. The signal's effects appear to be permanent. The findings, published in the June 7 issue of Science, outline what may be a new avenue to explore in the search for brain-damage and paralysis treatments, the researchers say.

Messages move through the average neuron like tributaries flowing into a river. The tributaries are called dendrites, and they flow into the axon, the river itself, which in turn can share messages with dendrites further downstream.

When Reeve fell from his horse, neurons that weren't killed outright may have had their axons chopped in half, disconnecting them from the network. "This is the core problem in neural degenerative diseases, especially things like spinal cord injury. Axons that get cut don't grow past the site of the injury back to normal connections in the brain," said Jeffrey Goldberg, lead author of the paper and senior graduate student in the lab of Ben A. Barres, MD, PhD, associate professor of neurobiology and developmental biology. "When a person is paralyzed, that's permanent," he said.

Left to their own devices, neurons in the central nervous system grow back so slowly that they o
'"/>

Contact: Amy Adams
amyadams@stanford.edu
650-723-3900
Stanford University Medical Center
6-Jun-2002


Page: 1 2 3

Related biology news :

1. Tiny molecules have big potential as cancer drugs, Stanford researcher believes
2. Stanford researchers findings may shed light on common, deadly birth defect
3. Leukemia stem cells identified by Stanford researchers
4. New view of leukemia cells identifies best treatment options, Stanford researchers say
5. Confidentiality of genetic databases questioned by Stanford researchers
6. Stanford researchers go from heaven to Earth in lifeguard test
7. Transplant rejection averted by simple light exposure in Stanford animal study
8. Fat cells heal skull defects in mice, Stanford research shows
9. Gene-based screen sorts cancer cases, say Stanford researchers
10. Elusive but ubiquitous microbe fingered as gum disease culprit in Stanford study
11. Sticklebacks reveal secrets to evolutionary change in Stanford study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2020)... FREDERICK, Md. (PRWEB) , ... ... ... a leading provider of gene-to-protein and monoclonal antibody development services, today announced ... of protein-based products and services to the pharmaceutical, diagnostics, and research industries. ...
(Date:6/23/2020)... ... ... The field of quantitation of large molecules or proteins has been around for a ... of mass spectrometry in this field has gained a lot of momentum in the ... approach to use (LBA or MS)?” In many cases, either technology can answer ...
(Date:6/23/2020)... ... June 23, 2020 , ... In its June 22 online post, business and ... L. Sherley, M.D., Ph.D., founder and director of stem cell biotechnology company Asymmetrex ... 16 that starting July 5 it would begin offering free tissue stem ...
Breaking Biology News(10 mins):
(Date:6/28/2020)... ... ... The Indoor Lab, a leading provider of sensor solutions for monitoring foot ... ensure cleanliness, distancing and occupancy with its patent pending WipeAway™ technology using Artificial Intelligence ... a health performance index system that scores all aspects of compliance similar to the ...
(Date:6/28/2020)... ... June 26, 2020 , ... The Security Industry Association ... strong opposition to the recently introduced bicameral Facial Recognition and Biometric Technology ... federal use of nearly all biometric and related image analytics technologies, incorrectly labeling ...
(Date:6/23/2020)... ... 22, 2020 , ... Regen Suppliers, the one stop shop ... three, get the fourth unit free with no limit on the amniotic derived ... exosomes, have been a game changer for regenerative therapies. The products are manufactured ...
(Date:6/19/2020)... (PRWEB) , ... June 18, 2020 , ... The ... Its goal is to join forces to radically prolong life and find a way ... the aging period. This project was supported by various scientists from all over the ...
Breaking Biology Technology:
Cached News: