HOME >> BIOLOGY >> NEWS
Stanford explores new avenue for brain injury, paralysis research

STANFORD, Calif. - The central nervous system, made up of the brain and spinal cord, never forgets a slight. Somehow, nerve cells lose the ability to regenerate: witness actor Christopher Reeve's paralysis after his horse threw him at a jump. To find a cure for such injuries, scientists must understand why nerve cells lose the ability to grow back. They know that these cells - called neurons - stop regenerating because a signal tells them to slow down during development. The problem is, scientists haven't known much about that signal.

Now, a team of Stanford University Medical Center researchers have identified the mechanism and some key cells involved in controlling regeneration. It turns out that the signal to slow down doesn't come from the neurons themselves, but from an outside source. The signal's effects appear to be permanent. The findings, published in the June 7 issue of Science, outline what may be a new avenue to explore in the search for brain-damage and paralysis treatments, the researchers say.

Messages move through the average neuron like tributaries flowing into a river. The tributaries are called dendrites, and they flow into the axon, the river itself, which in turn can share messages with dendrites further downstream.

When Reeve fell from his horse, neurons that weren't killed outright may have had their axons chopped in half, disconnecting them from the network. "This is the core problem in neural degenerative diseases, especially things like spinal cord injury. Axons that get cut don't grow past the site of the injury back to normal connections in the brain," said Jeffrey Goldberg, lead author of the paper and senior graduate student in the lab of Ben A. Barres, MD, PhD, associate professor of neurobiology and developmental biology. "When a person is paralyzed, that's permanent," he said.

Left to their own devices, neurons in the central nervous system grow back so slowly that they o
'"/>

Contact: Amy Adams
amyadams@stanford.edu
650-723-3900
Stanford University Medical Center
6-Jun-2002


Page: 1 2 3

Related biology news :

1. Tiny molecules have big potential as cancer drugs, Stanford researcher believes
2. Stanford researchers findings may shed light on common, deadly birth defect
3. Leukemia stem cells identified by Stanford researchers
4. New view of leukemia cells identifies best treatment options, Stanford researchers say
5. Confidentiality of genetic databases questioned by Stanford researchers
6. Stanford researchers go from heaven to Earth in lifeguard test
7. Transplant rejection averted by simple light exposure in Stanford animal study
8. Fat cells heal skull defects in mice, Stanford research shows
9. Gene-based screen sorts cancer cases, say Stanford researchers
10. Elusive but ubiquitous microbe fingered as gum disease culprit in Stanford study
11. Sticklebacks reveal secrets to evolutionary change in Stanford study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/18/2016)... LONDON , March 18, 2016 ... Established Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical ... & security companies in the border security market and ... and Europe has led ... your companies improved success. --> defence & ...
(Date:3/15/2016)... , March 15, 2016 Yissum ... , the technology-transfer company of the Hebrew University, announced ... of remote sensing technology of various human biological indicators. ... raising $2.0 million from private investors. ... based on the detection of electromagnetic emissions from sweat ...
(Date:3/11/2016)... , March 11, 2016 http://www.apimages.com ) - ... reference: Picture is available at AP Images ( http://www.apimages.com ) - ... will be used to produce the new refugee identity cards. DERMALOG ... innovations, at CeBIT in Hanover next week.   ... DERMALOG will be used to produce the new refugee identity cards. ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... ... April 29, 2016 , ... Intelligent Implant Systems announced today ... via 510(k) for sale in the United States. These components expand the capabilities ... With one-level sales beginning in October of 2015, the company has seen significant ...
(Date:4/28/2016)... ... 28, 2016 , ... Connecticut Innovations (CI), the ... announced the launch of VentureClash , a $5 million global investment challenge ... looks to attract the best early-stage companies here in Connecticut, around the country ...
(Date:4/27/2016)... ... ... Cambridge Semantics, the leading provider of Smart Data analytic and ... named to The Silicon Review’s “20 Fastest Growing Big Data Companies of 2016.” ... needs of end users facing some of the most complex data challenges in the ...
(Date:4/27/2016)... 2016 NanoStruck Technologies Inc. ... ( Frankfurt : 8NSK) gibt bekannt, ... 13. August 2015 die Genehmigung von der CNSX ... 200.000.000 Einheiten auf 400.000.000 Einheiten zu erhöhen, um ... wurden 157.900.000 Einheiten mit dem ersten Teil der ...
Breaking Biology Technology:
Cached News: