HOME >> BIOLOGY >> NEWS
Stanford explores new avenue for brain injury, paralysis research

STANFORD, Calif. - The central nervous system, made up of the brain and spinal cord, never forgets a slight. Somehow, nerve cells lose the ability to regenerate: witness actor Christopher Reeve's paralysis after his horse threw him at a jump. To find a cure for such injuries, scientists must understand why nerve cells lose the ability to grow back. They know that these cells - called neurons - stop regenerating because a signal tells them to slow down during development. The problem is, scientists haven't known much about that signal.

Now, a team of Stanford University Medical Center researchers have identified the mechanism and some key cells involved in controlling regeneration. It turns out that the signal to slow down doesn't come from the neurons themselves, but from an outside source. The signal's effects appear to be permanent. The findings, published in the June 7 issue of Science, outline what may be a new avenue to explore in the search for brain-damage and paralysis treatments, the researchers say.

Messages move through the average neuron like tributaries flowing into a river. The tributaries are called dendrites, and they flow into the axon, the river itself, which in turn can share messages with dendrites further downstream.

When Reeve fell from his horse, neurons that weren't killed outright may have had their axons chopped in half, disconnecting them from the network. "This is the core problem in neural degenerative diseases, especially things like spinal cord injury. Axons that get cut don't grow past the site of the injury back to normal connections in the brain," said Jeffrey Goldberg, lead author of the paper and senior graduate student in the lab of Ben A. Barres, MD, PhD, associate professor of neurobiology and developmental biology. "When a person is paralyzed, that's permanent," he said.

Left to their own devices, neurons in the central nervous system grow back so slowly that they o
'"/>

Contact: Amy Adams
amyadams@stanford.edu
650-723-3900
Stanford University Medical Center
6-Jun-2002


Page: 1 2 3

Related biology news :

1. Tiny molecules have big potential as cancer drugs, Stanford researcher believes
2. Stanford researchers findings may shed light on common, deadly birth defect
3. Leukemia stem cells identified by Stanford researchers
4. New view of leukemia cells identifies best treatment options, Stanford researchers say
5. Confidentiality of genetic databases questioned by Stanford researchers
6. Stanford researchers go from heaven to Earth in lifeguard test
7. Transplant rejection averted by simple light exposure in Stanford animal study
8. Fat cells heal skull defects in mice, Stanford research shows
9. Gene-based screen sorts cancer cases, say Stanford researchers
10. Elusive but ubiquitous microbe fingered as gum disease culprit in Stanford study
11. Sticklebacks reveal secrets to evolutionary change in Stanford study

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Stanford explores new avenue for brain injury paralysis research

(Date:12/17/2014)... BELVOIR, Va. , Dec. 15, 2014 The ... it easier to detect and prevent counterfeit microcircuits from ... agency started performing an in-house microcircuit anti-counterfeit initiative dubbed ... purchased microcircuits while increasing their reliability throughout the supply ...
(Date:12/15/2014)... Markets ( http://www.researchandmarkets.com/research/87pph8/global_facial ) has announced the ... report to their offering. ... technology used for the identification of individuals. Facial recognition ... such as nose, jaw edges, mouth, and the distance ...
(Date:12/10/2014)... here before: you desperately need to sign into your online banking ... to your secret question. What,s your dog,s birthday? Who was your ... a digital infrastructure security company, launches the app that ... usernames, passwords and PINs – 1U TM . 1U ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
(Date:1/22/2015)... , Nueva Jersey , 22 de enero de ... Biomedical Research abre hoy su llamada a nominaciones para ... investigación científica ha hecho, o tiene el potencial para ... humana. Las nominaciones se aceptarán hasta el 15 de ...
(Date:1/22/2015)... PRINCETON, N.J. , Jan. 22, 2015  Derma ... tissue regeneration company focused on advanced wound care, ... from placental tissues, have been added to the ... announcement increases the opportunity for the AMNIOEXCEL® and ...
(Date:12/24/2014)... AUSTIN, Texas , Dec. 24, 2014  Vermillion, ... focused on gynecologic disease, announced today that the ... investors including Oracle Investment Management, Jack W. ... directors. Total proceeds were $10.5 million, before offering ...
(Date:12/24/2014)... Earlier this year in a June 24 ... Adult Stem Cell Technology Center, LLC ( ASCTC ) focused ... of adult tissue stem cells. His title “Asymmetric Self-Renewal ... the Future,” embodied the essence of his message to congress ...
Breaking Biology Technology:El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4
Cached News: