HOME >> BIOLOGY >> NEWS
Stanford researchers make lung cancer finging that could vastly improve treatment and outcome

STANFORD, Calif. - Researchers at the Stanford University Medical Center have uncovered a group of genes that could distinguish between different forms of lung cancer. This finding may help doctors predict individual treatment strategies and may someday lead to better lung cancer drugs.

"What this means is that we can distinguish between different types of lung cancers, which was not possible before, and that those differences have clinical consequences," said David Botstein, MD, professor of genetics and senior author on the study, published in the Proceedings of the National Academy of Sciences on Nov. 13.

Doctors currently categorize lung tumors into one of four types: small cell, squamous cell, large cell and adenocarcinoma. When doctors diagnose a small-cell tumor, they can provide a fairly accurate prognosis. But other tumor types, particularly adenocarcinomas, respond very differently to standard treatment.

"Lung adenocarcinomas may appear morphologically similar, however, the patients differ in survival and possibly drug sensitivity," said Mitchell Garber, a post-doctoral student and first author on the paper. "At present, the pathologist cannot determine patient survival for those diagnosed with adenocarcinoma."

Garber thought these differences may arise from gene variations within the tumor. If that's the case, doctors would have an additional tool for distinguishing how tumors will grow, helping to determine the best course of treatment for each patient. "The short-term goal is to know the fingerprint of a tumor that has a poor prognosis," Garber said. "That will give the clinician an incentive to look a little harder within this patient for additional tumors."

To find out whether genetic differences exist between lung tumors, Garber obtained RNA from 67 lung tumor samples and six normal lung samples. RNA is produced by active genes and can be used to identify which genes are being expressed in a given sample. He t
'"/>

Contact: Sheila Foster
sheila.foster@stanford.edu
650-723-3900
Stanford University Medical Center
15-Nov-2001


Page: 1 2 3

Related biology news :

1. Tiny molecules have big potential as cancer drugs, Stanford researcher believes
2. Stanford researchers findings may shed light on common, deadly birth defect
3. Leukemia stem cells identified by Stanford researchers
4. New view of leukemia cells identifies best treatment options, Stanford researchers say
5. Confidentiality of genetic databases questioned by Stanford researchers
6. Stanford researchers go from heaven to Earth in lifeguard test
7. Transplant rejection averted by simple light exposure in Stanford animal study
8. Fat cells heal skull defects in mice, Stanford research shows
9. Gene-based screen sorts cancer cases, say Stanford researchers
10. Elusive but ubiquitous microbe fingered as gum disease culprit in Stanford study
11. Sticklebacks reveal secrets to evolutionary change in Stanford study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... (PRWEB) , ... August 14, 2019 , ... Join Jonathan ... live session on Tuesday, September 10, 2019 at 1pm EDT to learn about ... and effective management. , NAFLD is the most common diffuse liver disease, with ...
(Date:8/14/2019)... JOLLA, Calif. (PRWEB) , ... August 14, 2019 , ... ... insight into their future children, announces inclusion in the 38th annual Inc. 500|5000 ... been eligible to apply. To qualify, companies must have been founded and generating revenue ...
(Date:8/14/2019)... ... ... Julie Reck of Veterinary Medical Center of Fort Mill has recently begun providing ... her own geriatric Australian Shepherd, Simon, was treated in June 2019 for osteoarthritis in his ... body was weak, and he struggled to play fetch and other games with his family. ...
Breaking Biology News(10 mins):
(Date:6/12/2019)... ... June 12, 2019 , ... ... testing instruments for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries, is ... signed. The agreement will grant exclusive rights for Zillion to represent LDA in ...
(Date:6/11/2019)... ... 10, 2019 , ... DeepDyve and IOP ... to DeepDyve’s rental service for peer-reviewed journals. , IOPP’s portfolio represents an ... 20 million articles, sourced from more than 15,000 journals. , “By partnering with ...
(Date:6/11/2019)... ... June 11, 2019 , ... A study released ... cells (MSC-EV) are able to incorporate into human CD34+ cells, modifying their gene ... MSC-EVs also increased the cells’ ability to lodge into bone marrow. This research ...
(Date:5/31/2019)... ... May 29, 2019 , ... ... proprietary interest to our methodology, processes, and diagnostic techniques. The patent applications ... Somnology’s IP rights including our proprietary sleep scoring methodology. The approval and ...
Breaking Biology Technology:
Cached News: