HOME >> BIOLOGY >> NEWS
Staph bacteria are prolific gene swappers, researchers show

When some disease-causing bacteria encounter a new obstacle, they simply swap DNA with their relatives to acquire the genes needed to overcome it. And they do so quite readily, according to scientists from the National Institute of Allergy and Infectious Diseases (NIAID). The research reveals how Staphylococcus aureus, the common "staph" bacterium responsible for several human infections, has repeatedly adapted to novel environments and conditions. The research offers new approaches to antibiotic and vaccine design, and answers long-standing questions about the origins of two diseases: toxic shock syndrome (TSS) and antibiotic-resistant infections.

"We have long wondered how TSS and methicillin-resistant staph strains took hold in the population," says study director James Musser, M.D., Ph.D., a bacteria researcher from NIAID's Rocky Mountain Laboratories in Hamilton, Mont. "The debate among microbiologists has been, did isolated strains pick up new genes once and then spread through the population, or did the bacteria acquire the genes on multiple occasions? Our research clearly shows the second explanation is correct."

The discovery likely settles the debate, Dr. Musser explains, and raises a concern about how easily bacteria can become dangerous. S. aureus is a common microbe that often causes no illness. Some strains can cause diseases, however, including TSS, food poisoning and impetigo. The bacteria can infect the skin, blood, urinary tract and wounds, and are a common source of infections acquired in hospitals. Most people are unknowing S. aureus carriers, intermittently harboring the bacteria on their skin or in their nose and throat, even in the absence of illness.

Whether or not a particular S. aureus strain causes disease depends largely on its genes. Different strains can survive different environments, and Dr. Musser's team sought to learn how genes have been exchanged between strains. In the study reported in today's
'"/>

Contact: Sam Perdue
sp189u@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
9-Jul-2001


Page: 1 2

Related biology news :

1. Staph aureus bacteremia in ESRD patients associated with substantial illness and higher costs
2. An aspirin a day keeps Staphylococcus aureus away
3. Discovery of iron-acquisition pathway suggests new treatments for drug-resistant Staph. infections
4. The growing Staphylococcus aureus arsenal
5. Surprising role for Staphs toxic shock toxin
6. Nabi experimental vaccine reduced Staph aureus bloodstream infections by nearly 60 percent
7. Experimental Staph Vaccine Broadly Protective In Animal Studies
8. Researchers find color sensitive atomic switch in bacteria
9. Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
10. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
11. Scientists discover potential new way to control drug-resistant bacteria

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/8/2019)... ... January 07, 2019 , ... ... solutions, is proud to welcome Thomas Kennedy as head of sales and business ... for PureWay. , Mr. Kennedy has previously worked for Johnson & Johnson Medical, ...
(Date:1/4/2019)... ... January 02, 2019 , ... Lifecycle Biotechnologies ... the life science tools and service supplier turned 40 in 2018 and for ... catalog features not just part numbers like most catalogs, but rather, insightful information ...
(Date:12/25/2018)... ... 2018 , ... Researchers at the Icahn School of Medicine ... a long-standing computational concept known as “blacklisting,” which is commonly employed as a ... as a filter to single out genetic variations in patient genomes and exomes ...
Breaking Biology News(10 mins):
(Date:1/8/2019)... ... January 08, 2019 , ... The American Society of ... were named by a selection committee made up of industry leaders identified by the ... Development grants are mentored awards created to support ASGCT members designing transformative pilot studies ...
(Date:1/4/2019)... (PRWEB) , ... January 01, 2019 , ... ... first Microbiome Conference at the World Economic Forum Annual Meeting January 22-25, 2019 ... conference is invitation-only. , The World Economic Forum Annual Meeting brings together leaders ...
(Date:12/20/2018)... ... ... New Year’s brings reflection and desire to improve for individuals and businesses ... on the horizon, Jim Kasic, president and CEO of Boulder iQ, suggests five resolutions ... Regulation (MDR), digital health, and big data are just a few of the challenges ...
(Date:12/18/2018)... ... December 17, 2018 , ... ABCT , ... biosciences ventures invited to participate in the annual program. Twelve ventures will participate ... and a professional network. All startups receive an entrepreneur coach, access to active ...
Breaking Biology Technology:
Cached News: