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Structure solved by Scripps scientists shows one way that body controls gene expression

ach other, the TIS11d protein binds to the mRNA by forming hydrogen bonds with the Watson-Crick edges of the mRNA.

"It was remarkable to see how these tiny structures [work]," says Wright.

The research article "Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d" is authored by Brian P. Hudson, Maria A. Martinez-Yamout, H. Jane Dyson, and Peter E. Wright and appears in the March 2004 issue of Nature Structural & Molecular Biology.


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Contact: Keith McKeown
kmckeown@scripps.edu
858-784-8134
Scripps Research Institute
13-Feb-2004


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