HOME >> BIOLOGY >> NEWS
Study links diabetes and colorectal cancer

Diabetics are three times more likely to develop colorectal cancer than people with normal blood sugar levels, according to a team of scientists at the University of Cambridge, U.K., reporting in this month's edition of the journal Cancer Epidemiology, Biomarkers and Prevention.

The researchers found a continuous relationship between glycated hemoglobin (HbA1c) concentrations and colorectal cancer risk, even in individuals not known to have diabetes.

"When both glycated hemoglobin levels and diabetes status were included as variables in the same model, glycated hemoglobin remained a significant predictor of colorectal cancer risk, while the effect of diabetes was not significant," said Kay-Tee Khaw, M.D., FRCP, professor in the clinical gerontology unit of the university's School of Clinical Medicine, and principal investigator for the study. "The significantly increased risk of diabetes with colorectal cancer appeared to be mediated largely through the level of glycated hemoglobin."

Khaw noted further that glycated HbA1c could predict colorectal cancer independently of diabetes and such other risk factors as obesity and cigarette smoking and do so at concentrations below those commonly accepted as the standard for a diagnosis of diabetes.

For every one percent increase in glycated hemoglobin there was a corresponding 33 percent increase in risk across the population.

The results are based on data derived from the European Investigation into CancerNorfolk Study, a prospective population study of the connection between diet and cancer. Participants, more than 30,000 men and women, ages 45 to 79, who live in Norfolk, U.K., completed health and lifestyle questionnaires and received medical examinations. Non-fasting blood samples were drawn. Khaw and her colleagues measured glycated hemoglobin levels in the blood of the nearly 10,000 people for whom the information was available, and who did not report having cancer at th
'"/>

Contact: Elizabeth Tait
tait@aacr.org
215-440-9300
American Association for Cancer Research
4-Jun-2004


Page: 1 2

Related biology news :

1. Study: Emission of smog ingredients from trees is increasing rapidly
2. Study explores gene transfer to modify underlying course of Alzheimers disease
3. Study reveals why eyes in some paintings seem to follow viewers
4. Study by Israeli scientists provides insight on DNA code
5. Study reveals first genetic step necessary for prostate cancer growth
6. Study of flu patients reveals virus outsmarting key drug
7. Study in Science reveals recreational fishing takes big bite of ocean catch
8. Study suggests cell-cycle triggers might be cancer drug targets
9. Study narrows search for genes placing men at increased risk for prostate cancer
10. Study links high carbohydrate diet to increased breast cancer risk
11. Study explains spatial orientation differences between sexes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: