HOME >> BIOLOGY >> NEWS
Study narrows search for genes placing men at increased risk for prostate cancer

August 18, Phoenix, AZ--Scientists at the Translational Genomics Research Institute (TGen), Johns Hopkins Medical Institutions, the National Institutes of Health, The University of Michigan and five other research institutes world-wide announced today the findings from the largest study of the genetics of prostate cancer undertaken to date. Results have zeroed in on three different regions of the genome containing genes that may make men more vulnerable to this common cancer. Prostate cancer is the second-leading cause of cancer death in US men. The findings appear in the August 18 issue of the Journal of the National Cancer Institute.

The researchers are currently scouring those genome regions, culled from more than 400 cancer-prone families, to identify specifically which genes lead to increased prostate cancer susceptibility.

"This study will help us predict better who is at the highest risk for this disease," says the paper's lead author, Dr. Elizabeth Gillanders, a scientist at the National Institutes of Health in Bethesda, MD. "If we could identify men with susceptibility genes, we can target our surveillance to them and identify their cancers much earlier. Early-stage treatment is far more beneficial in prostate cancer," she says.

In addition, she noted, prostate cancers in men who possess susceptibility genes tend to be more aggressive--and more often fatal--than prostate cancers in men who are not genetically prone to the disease.

"This study focuses and intensifies the hunt for genes that increase a man's risk of prostate cancer," says the paper's senior author, Dr. Jeffrey M. Trent, Scientific Director of TGen in Phoenix, Arizona. "We needed this sort of massive study in order to have the power to target important genome regions."

"The difference between this paper and previous work on the genetics of prostate cancer is the number of families studied," says Dr. William B. Isaacs, of the Johns Hopkins University in
'"/>

Contact: Galen P. Perry
gperry@tgen.org
602-343-8423
The Translational Genomics Research Institute
17-Aug-2004


Page: 1 2 3

Related biology news :

1. Study: Emission of smog ingredients from trees is increasing rapidly
2. Study explores gene transfer to modify underlying course of Alzheimers disease
3. Study reveals why eyes in some paintings seem to follow viewers
4. Study by Israeli scientists provides insight on DNA code
5. Study reveals first genetic step necessary for prostate cancer growth
6. Study of flu patients reveals virus outsmarting key drug
7. Study in Science reveals recreational fishing takes big bite of ocean catch
8. Study suggests cell-cycle triggers might be cancer drug targets
9. Study links high carbohydrate diet to increased breast cancer risk
10. Study explains spatial orientation differences between sexes
11. Study suggests humans can speed evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... MELBOURNE, Florida , April 11, 2017 ... "Company"), a security technology company, announces the appointment of independent ... John Bendheim to its Board of Directors, furthering the ... ... behalf of NXT-ID, we look forward to their guidance and ...
(Date:4/5/2017)... 4, 2017 KEY FINDINGS The ... at a CAGR of 25.76% during the forecast period ... primary factor for the growth of the stem cell ... MARKET INSIGHTS The global stem cell market ... and geography. The stem cell market of the product ...
(Date:3/30/2017)... HONG KONG , March 30, 2017 ... developed a system for three-dimensional (3D) fingerprint identification by adopting ground ... technology into a new realm of speed and accuracy for use ... applications at an affordable cost. ... ...
Breaking Biology News(10 mins):
(Date:7/26/2017)... ... July 26, 2017 , ... ... complex problems we face every day. This unique capability combines high resolution ... chemists, and manufacturers to deliver unprecedented datasets for chemical analysis, quality control, and ...
(Date:7/26/2017)...  Nurse practitioners play a crucial role in helping patients ... Merck Manuals survey released today. The survey of 210 ... (88 percent) believe they spend at least half of appointment ... ... Manuals survey of 210 nurse practitioners finds that 78% of ...
(Date:7/24/2017)... , ... July 24, 2017 , ... Charm Sciences, Inc. ... accepted by the National Conference on Interstate Milk Shipments (NCIMS) Laboratory Committee and Appendix ... set to launch July 1, 2017. , The NCIMS voted at its annual meeting ...
(Date:7/20/2017)... ... July 20, 2017 , ... ... ., the Elihu Thomson Professor of Electrical Engineering and Computer Science at the ... winner. Presented annually, the award recognizes an individual who has made and is ...
Breaking Biology Technology:
Cached News: