HOME >> BIOLOGY >> NEWS
Study reveals structure of DNA packaging motor in virus

To view a Quicktime movie of the DNA packaging motor, click here. Requires Quicktime 3 or higher.

WEST LAFAYETTE, Ind. - A detailed look at one of nature's smallest motors is providing scientists with new insights on how some viruses package their genetic material and reveals a new type of biological motor system.

Scientists at Purdue University and the University of Minnesota have solved the three-dimensional structure of the central component of a biological "motor" that powers the DNA packaging system in a virus, providing scientists with their first glimpse of such a motor system.

The study describes atom-by-atom how the core of the tiny motor, just millionths of a millimeter in size, is constructed and suggests how it works to translocate, or pack, long stretches of the virus' genetic material into its outer shell during the process of viral replication.

Details appear in the Dec. 7 issue of the scientific journal Nature.

"This study provides the first knowledge of a DNA packaging motor," says Michael Rossmann, Hanley Distinguished Professor of Biological Sciences at Purdue. "Though other motor systems have been studied in biology, this is the first motor known to translocate genetic material."

Viruses are essentially a simple parasite consisting only of an envelope that contains the genetic material ready for transportation from one host to another. They can reproduce only after infecting a host cell. Once inside a cell, the virus manipulates the cell's machinery to produce all the necessary components, including genetic material, to assemble new viruses. It is here that the biological motor is needed to fill newly assembled envelopes with their genetic material, Rossmann says. The new viruses are then released from the host cell and are free to infect other cells.

The study may provide clues as to how DNA is packaged in similar
'"/>

Contact: Susan Gaidos
sgaidos@purdue.edu
765-494-2081
Purdue University
6-Dec-2000


Page: 1 2 3

Related biology news :

1. Study: Emission of smog ingredients from trees is increasing rapidly
2. Study explores gene transfer to modify underlying course of Alzheimers disease
3. Study reveals why eyes in some paintings seem to follow viewers
4. Study by Israeli scientists provides insight on DNA code
5. Study reveals first genetic step necessary for prostate cancer growth
6. Study of flu patients reveals virus outsmarting key drug
7. Study in Science reveals recreational fishing takes big bite of ocean catch
8. Study suggests cell-cycle triggers might be cancer drug targets
9. Study narrows search for genes placing men at increased risk for prostate cancer
10. Study links high carbohydrate diet to increased breast cancer risk
11. Study explains spatial orientation differences between sexes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... June 15, 2017  IBM (NYSE: IBM ) is introducing ... event dedicated to developing collaboration between startups and global businesses, ... 15-17. During the event, nine startups will showcase the solutions ... various industries. France ... market, with a 30 percent increase in the number of ...
(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
(Date:4/17/2017)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... 2016 Annual Report on Form 10-K on Thursday April 13, 2017 ... ... Investor Relations section of the Company,s website at http://www.nxt-id.com  under ... http://www.sec.gov . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:9/21/2017)... ... September 21, 2017 , ... When a downtown Greenville ... was swift and efficient thanks to the continuing efforts of members of the ... more than 50 stakeholders, including officials from area counties and cities, Renewable Water ...
(Date:9/20/2017)... ... September 20, 2017 , ... The ... Agronomic Services (Koch) to feature new innovations aimed at helping farmers solve the ... 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. Check your local listings ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... global provider of engineering, architecture, project controls, construction management, commissioning and qualification ... announced the unveiling of the iCON™ brand which represents the collective facility ...
(Date:9/20/2017)... ... September 20, 2017 , ... From industry leaders, sports stars, ... standard medicine failed. Many of these people had lost all hope. Their ... Free Download (pdf) , “Neil takes readers on a riveting journey ...
Breaking Biology Technology:
Cached News: