Study suggests way to short-circuit microbe communication

MADISON - For cell-phone toting humans, the ability to communicate depends on a vast array of technology that includes things like amplifiers and repeaters to speed our words through the ether and ensure their intact arrival at a distant location.

Now, scientists have learned that bacteria use an analogous integrated communications system to sense, retrieve and process the chemical signals they depend on to find nutrients or flee from danger. The new finding, reported today (Jan. 3) in the journal Nature, may help scientists unravel the secrets of how cells communicate with one another, a development that could, among other things, spur new vaccine strategies or the creation of surfaces that naturally repel pathogenic microbes.

Bacteria - and other types of cells - use receptors on their surface to sense their environment and, like a human nose, pick up chemical cues from a distance, said Laura L. Kiessling, a University of Wisconsin-Madison professor of chemistry and biochemistry and the senior author of the Nature paper.

"The receptors act like a sensory organ and help the cell integrate and respond to many different signals," said Kiessling who conducted the study with UW-Madison graduate student Jason E. Gestwicki.

Scientists have long known that the membrane-spanning receptors on cells are conduits of chemical information. What they did not know, according to Kiessling, is that clusters of receptors on the cell surface act in concert to "amplify and integrate sensory information."

In their Nature paper, Kiessling and Gestwicki use a new type of signal, a synthetic multivalent attractant that can interact with several chemoreceptors, to control bacterial responses. They found that the four major types of surface chemoreceptors - each responsible for sensing particular compounds - work as a system to sense their environment and let the cell know whether to move toward or away from the source of a chemical signal.


Contact: Laura Kiessling
University of Wisconsin-Madison

Page: 1 2 3

Related biology news :

1. Study: Emission of smog ingredients from trees is increasing rapidly
2. Study explores gene transfer to modify underlying course of Alzheimers disease
3. Study reveals why eyes in some paintings seem to follow viewers
4. Study by Israeli scientists provides insight on DNA code
5. Study reveals first genetic step necessary for prostate cancer growth
6. Study of flu patients reveals virus outsmarting key drug
7. Study in Science reveals recreational fishing takes big bite of ocean catch
8. Study suggests cell-cycle triggers might be cancer drug targets
9. Study narrows search for genes placing men at increased risk for prostate cancer
10. Study links high carbohydrate diet to increased breast cancer risk
11. Study explains spatial orientation differences between sexes

Post Your Comments:

(Date:4/1/2019)... , ... April 01, 2019 , ... Stay on top ... medical device and food industries. Access to all webinars is free, so be sure ... in your field! , Visit http://www.xtalks.com to see our upcoming webinars: , ...
(Date:3/29/2019)... ... March 29, 2019 , ... ... biomanufacturing systems, will attend the Society for Biomaterials Annual Meeting & Exposition on ... opportunity to connect with academic, healthcare, governmental and business professionals in all aspects ...
(Date:3/26/2019)... (PRWEB) , ... March 26, 2019 , ... ... proud to introduce the four recipients of the Society's 2019 Outstanding Achievement Award, ... four awards will be presented at the ASGCT 22nd Annual Meeting . ...
Breaking Biology News(10 mins):
(Date:4/12/2019)... Fla. (PRWEB) , ... April 12, 2019 , ... ... explore recent developments in neurotechnology and will educate about innovative tools and devices ... Check your local listings for more information. , This segment of Advancements will ...
(Date:4/10/2019)... ... April 10, 2019 , ... After more than three months of renovation, Lajollacooks4u ... equipped with updated appliances and modern lighting and fixtures, and will provide additional workspace ... “We’ve seen tremendous growth in the demand for our team-building events and cooking classes ...
(Date:4/9/2019)... ... April 09, 2019 , ... Sonny Bar Lisa, or Sonny ... for approximately two months. After a series of diagnostics, an MRI was performed ... owner, Alison, researched the injury and found that VetStem Regenerative Cell Therapy ...
(Date:4/8/2019)... ... April 08, 2019 , ... CallTower, ... announced today the launch of their app integration solution, CT Cloud Unite. ... contact-orientated applications while using CT Cloud Voice and Skype for Business solutions. This ...
Breaking Biology Technology:
Cached News: