HOME >> BIOLOGY >> NEWS
Survey reports fall in stem cell transplants for breast cancer

The use of stem cell transplantation in breast cancer treatment soared in the early and mid 1990s but the dramatic fall that begin in 1997 as clinical trials showed it appeared to be of little benefit continues, according to new figures published in the April edition of Annals of Oncology[1].

Nearly 28,000 stem cell transplants were carried out for various types of solid tumours in Europe between 1991 and 2002. Breast cancer accounted for around half of the procedures (more than 13,500). Breast cancer transplants rose from 94 in 1991 to 2,629 in 1997 on the back of promising results from phase II clinical trials where transplants were combined with high-dose chemotherapy. But, as phase III trial results showed the treatment was failing to live up to earlier hopes, they dropped dramatically and the latest figures show that they were down to 330 in 2002.

The findings are from a survey carried out by an international team on behalf of the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT) and in co-operation with the Working Party on Solid Tumours and the Working Party on Paediatric Diseases.

Seven other specific types of solid tumours germ cell cancer (12%), neuroblastoma (9%), Ewing's sarcoma (7%), soft tissue sarcoma (4%), ovarian cancer (3%) glioma (2%) and lung cancer (1%), plus 'others' (13%) made up the transplant total. Ninety-eight per cent of the transplants were autologous (from the patient's own bone marrow) and two per cent were allogenic (from donors).

Lead author Professor Alois Gratwohl from the Department of Internal Medicine at Kantonsspital Basel in Switzerland, said: "In the early and mid-1990s impressive data from phase II trials as well as from registries accelerated the growth in the number of autotransplants for breast cancer. When the first results from phase III studies become available a wave of pessimism began to appear and the numbers undergoing high-dose chemother
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
44-153-677-2181
European Society for Medical Oncology
30-Mar-2004


Page: 1 2 3 4

Related biology news :

1. British Antarctic Survey wins environment award
2. Survey of Chesapeake Bay watershed residents may save the bay
3. Survey Shows Students Turning To Physicians Less As Drug Abuse Increases
4. Food Bacteria-Spice Survey Shows Why Some Cultures Like It Hot
5. U.S. Geological Survey 1998 Budget: Increased Support For Drinking Water, Earthquakes And Biological Sciences
6. APP reports Abraxane(TM) is active in breast cancer patients who failed taxol or taxotere
7. Scientists question reports of massive ant supercolonies in California and Europe
8. VaxGen reports Phase I clinical trial results of anthrax vaccine candidate
9. Immerge reports PERVs most infectious to human cells not part of germ-line DNA of mini-swine
10. By the year 2050, human population could add 2.6 billion people, reports Rockefeller scientist
11. Measles on the rise as vaccinations fall in the UK, Science study reports

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. (NASDAQ: ... announces the filing of its 2016 Annual Report on Form 10-K ... Commission. ... 10-K is available in the Investor Relations section of the Company,s ... the SEC,s website at http://www.sec.gov . 2016 Year ...
(Date:4/13/2017)... , April 13, 2017 According to a new ... Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, ... IAM Market is expected to grow from USD 14.30 Billion in 2017 ... (CAGR) of 17.3%. ... MarketsandMarkets Logo ...
(Date:4/11/2017)... Research and Markets has announced the addition ... their offering. ... tracking market to grow at a CAGR of 30.37% during the ... 2017-2021, has been prepared based on an in-depth market analysis with ... its growth prospects over the coming years. The report also includes ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Bay, Florida (PRWEB) , ... October 11, 2017 ... ... and Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel ... (sdAb) for the treatment of osteosarcoma. SBT-100 is able to cross the cell ...
(Date:10/10/2017)... International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, ... security market and how smart safety and security products impact the competitive ... Parks Associates: Smart Home Devices: Main ... "The residential security market has experienced continued ...
(Date:10/9/2017)... ... October 09, 2017 , ... The award-winning American Farmer television series will ... American Farmer airs Tuesdays at 8:30aET on RFD-TV. , With global population estimates ... of how to continue to feed a growing nation. At the same time, many ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... its ProxiMeta™ Hi-C metagenome deconvolution product, featuring the first commercially available Hi-C ... software to perform Hi-C metagenome deconvolution using their own facilities, supplementing the ...
Breaking Biology Technology:
Cached News: