Sweet success on the way to vaccine for ulcers, stomach cancer, reported in Science

This news release is also available in French and Swedish.

A spoonful of sugar may help the medicine go down, but for the 50 percent of the global population whose stomachs contain the Helicobacter pylori bacteria, other sugars have less sweet implications. Certain sugars in the body, meant to help the immune system fight the infection (which can lead to ulcers and stomach cancer), actually make the infection worse, according to a report in the journal Science, published by the American Association for the Advancement of Science.

These findings, by a team of Swedish, Estonian, French, and U.S. researchers, help explain why H. pylori is such a tenacious, virulent bug, and provide new prospects for making a vaccine against it.

There are many different strains of H. pylori, some more harmful than others. They cause virtually all ulcers (spicy food and stress do not) and have been linked to stomach cancer, one of the five most common types of cancer in the world, according to the World Health Organization.

H. pylori infections are far more common in the developing world than they are in North America and Europe, said study author Thomas Born of Ume University, in Ume, Sweden. He noted that, while ulcers can be treated with antibiotics, using this type of treatment globally would likely lead to the emergence of drug resistant bacterial strains.

"I think the real therapeutic strategy would be a vaccine," Born said.

During an H. pylori infection, when the bacteria are burrowing into the mucus membrane lining the stomach, the membrane cells display certain sugar molecules on their surfaces. The sugars help usher immune cells into the damaged tissue, but they have an unintended consequence as well, Born a

Contact: Lisa Onaga
American Association for the Advancement of Science

Page: 1 2

Related biology news :

1. Sweet success in targeting sugar molecules to cells in living animals
2. Bakers Yeast Causes Chemical Reactions And Sweet Smelling Labs
3. Inhibition Of A Novel Gene Involved In Phosphorylating Starch In TransgenicPotato Tubers Leads To The Repression Of Cold Induced Sweetening
4. Cancer Cells Self-Destruct When "Sweet Tooth" Is Thwarted
5. Phase II trials of second-generation antisense cancer drug planned following successful early study
6. UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies
7. Molecular marker predicts success of breast cancer treatment
8. Ecological success?
9. Land Regeneration Network celebrates first year success
10. Studies show success of Mectizan partnerships
11. Study of dyslexic brain finds three word forms responsible for reading success

Post Your Comments:

(Date:11/11/2019)... ... November 11, 2019 , ... MicroGenDX, the world leader in ... in the award-winning study “Next Generation Sequencing for the Diagnosis of Periprosthetic Knee ... processed samples using Next Generation DNA Sequencing to examine the ability of NGS ...
(Date:11/6/2019)... Va. (PRWEB) , ... November 06, 2019 , ... ... today that Donald Stanski, MD, a senior pharmaceutical industry executive with expertise in ... and simulation for drug and disease strategic data analytics, has joined the firm ...
(Date:11/5/2019)... WA (PRWEB) , ... November 05, 2019 , ... ... & Amato Dentistry, providing state-of-the-art cosmetic and restorative dentistry to Seattle, WA, including ... her Doctor of Dental Surgery degree from the University of Washington, Dr. Kopp ...
Breaking Biology News(10 mins):
(Date:11/27/2019)... ... November 25, 2019 , ... Silony Medical, a medical ... and navigated surgery in the UK. The procedure was performed in the UK’s ... Syed Aftab and Dr. Alexander Montgomery. The surgery, which took place on July ...
(Date:11/20/2019)... ... November 20, 2019 , ... Defense and ... microturbine electrical power generation units from 2019-2028. The value of this production is ... of 3,821 units worth $569 million. , Reference to 2017 is important, ...
(Date:11/12/2019)... ... November 12, 2019 , ... ... R&D, today announced that Immatics Biotechnologies , a clinical-stage biopharmaceutical company ... to streamline their R&D operations related to the discovery and development of ...
(Date:11/12/2019)... ... November 12, 2019 , ... ... to educate Americans about the deadly healthcare-associated infection C. diff. The campaign, ... of the epidemic, which kills at least 30,000 people in the U.S. each ...
Breaking Biology Technology:
Cached News: