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Tackling a 'hairy beast'

ce, Eisen said, by releasing the data immediately and by creating two interlinked database resources for researchers: a database of genomic information and annotation at TIGR and a manually curated Tetrahymena Genome Database at Stanford University. Eduardo Orias, Ph.D., of UC Santa Barbara will provide project liaison with the ciliate research community.

Major fundamental advances based on studies of Tetrahymena include determination of the structure and function of telomeres--the caps that protect the ends of chromosomes in eukaryotes--and the Nobel Prize-winning discovery that RNA can catalyze biochemical reactions.

"The results of this genome sequencing project will tell us much about how complex cells function and will also provide insight into the diversity and history of life on Earth," said Matthew Kane, Ph.D., Molecular and Cellular Biosciences program director for the National Science Foundation.

The three-year grant from NIGMS for Tetrahymena sequencing and analysis totals $3.87 million, and the two-year grant from NSF totals $2.56 million. The NIGMS grant also includes funds for database development.


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Contact: Linda Joy
linda.joy@nih.gov
301-402-2545
NIH/National Institute of General Medical Sciences
9-Apr-2003


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