HOME >> BIOLOGY >> NEWS
Taking a SNP in the gene pool: Scientists harvest human gene differences

What makes one person's genes different from another's? Very often, any difference is tiny: a change in one DNA base pair out of hundreds that make up a gene. Yet scientists are eager to catalog these base pair variations, known as single nucleotide polymorphisms, or SNPs, in the hopes of understanding how differences in our genes lead to differences in us. In the November issue of Genome Research, Kavita Garg, Philip Green, and Deborah Nickerson (University of Washington) report a method to identify common human SNPs located in active genes.

SNPs also arise in the large portion of DNA that does not encode active genes. To sift "coding" SNPs from such non-coding variations, Garg and colleagues made use of so-called cDNA "libraries," which are collections of active genes from one or more individuals. After searching each of 50 different libraries for known genes, they compared sequences from each library base by base to find representative differences between the individuals' genes. This approach yielded 201 coding SNPs, a promising harvest that suggests gene libraries will be a plentiful future source of important human SNPs.


'"/>

Contact: Peggy Calicchia
calicchi@cshl.org
516-367-6834
Cold Spring Harbor Laboratory
14-Nov-1999


Page: 1

Related biology news :

1. Taking aim at bioterrorism: UH professor gets HHS funding to battle anthrax
2. Taking the show on the road - Leading researchers to conduct hands-on science symposium for 500 San Francisco area high school students
3. Taking the long view: examining factors which influence Northern Spotted Owls
4. Taking the pulse of giants: Detecting change and its consequences in western mountain ecosystems
5. Taking vitamin supplements is a common behavior in the U.S.
6. Taking The Animal Out Of Animal Testing
7. Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients
8. National Science Foundation Is Taking Small Business Into A New Phase Of Innovation
9. Digging In And Taking Cover
10. Taking The "Ouch" Out Of Needles: Arrays Of "Microneedles" Offer New Technique For Drug Delivery
11. Intake Of Acetaminophen Increases Risk Of Excessive Anticoagulation In Patients Taking Warfarin

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/4/2020)... ... March 04, 2020 , ... VGXI, Inc., a ... has been nominated as a finalist in the category of Best Contract Manufacturing ... VGXI expedites manufacturing of a DNA vaccine against the novel coronavirus, COVID-19, under ...
(Date:3/2/2020)... ... 02, 2020 , ... Toronto-based clinical research organization (CRO) and regulatory consulting firm, ... just 5 minutes south of Clarksburg on a farm on Beaver Valley Road. , ... the Rainbow Orchard, and decided it would be a great new option for employees ...
(Date:2/28/2020)... (PRWEB) , ... February 28, 2020 , ... Meridian ... 2020 Vaccine Industry Excellence (ViE) award for Best Clinical Trial Site. Meridian ... finalist for the Best Clinical Trial Network award. These nominations were the result of ...
Breaking Biology News(10 mins):
(Date:3/4/2020)... ... March 04, 2020 , ... ... industry-leading provider of recombinant antibody products and services, today announced the launch ... flexibility to rapidly express a large number of antibodies at 80 ml ...
(Date:3/3/2020)... ... March 03, 2020 , ... ... pharmaceutical, biotech and medical device industries, was recognized by INC. 5,000 on an ... annual lists to note industry leaders greatly impacting their spheres of influence and ...
(Date:3/2/2020)... ... March 02, 2020 , ... McBee, Moore and Vanik IP, LLC (MMV ... field of Biotechnology and Organics. , According to statistics compiled by Harrity Anaytics, MMV ... issued in technology center 1600 during 2019. Technology center 1600 at the US Patent ...
(Date:2/26/2020)... Del. (PRWEB) , ... February 25, 2020 , ... ... DuPont Nutrition & Biosciences (DuPont) recently published the results of its safety assessment ... over 130 HMOs currently identified in human milk. These complex carbohydrates are indigestible ...
Breaking Biology Technology:
Cached News: