The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Taking a SNP in the gene pool: Scientists harvest human gene differences

What makes one person's genes different from another's? Very often, any difference is tiny: a change in one DNA base pair out of hundreds that make up a gene. Yet scientists are eager to catalog these base pair variations, known as single nucleotide polymorphisms, or SNPs, in the hopes of understanding how differences in our genes lead to differences in us. In the November issue of Genome Research, Kavita Garg, Philip Green, and Deborah Nickerson (University of Washington) report a method to identify common human SNPs located in active genes.

SNPs also arise in the large portion of DNA that does not encode active genes. To sift "coding" SNPs from such non-coding variations, Garg and colleagues made use of so-called cDNA "libraries," which are collections of active genes from one or more individuals. After searching each of 50 different libraries for known genes, they compared sequences from each library base by base to find representative differences between the individuals' genes. This approach yielded 201 coding SNPs, a promising harvest that suggests gene libraries will be a plentiful future source of important human SNPs.


'"/>

Contact: Peggy Calicchia
calicchi@cshl.org
516-367-6834
Cold Spring Harbor Laboratory
14-Nov-1999


Page: 1

Related biology news :

1. Taking aim at bioterrorism: UH professor gets HHS funding to battle anthrax
2. Taking the show on the road - Leading researchers to conduct hands-on science symposium for 500 San Francisco area high school students
3. Taking the long view: examining factors which influence Northern Spotted Owls
4. Taking the pulse of giants: Detecting change and its consequences in western mountain ecosystems
5. Taking vitamin supplements is a common behavior in the U.S.
6. Taking The Animal Out Of Animal Testing
7. Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients
8. National Science Foundation Is Taking Small Business Into A New Phase Of Innovation
9. Digging In And Taking Cover
10. Taking The "Ouch" Out Of Needles: Arrays Of "Microneedles" Offer New Technique For Drug Delivery
11. Intake Of Acetaminophen Increases Risk Of Excessive Anticoagulation In Patients Taking Warfarin

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Taking SNP the gene pool Scientists harvest human gene differences

(Date:11/23/2009)...sociated strain of the deadly superbug MRSAan infe...tibioticsposes a far greater health threat than pr...s, according to a study in the December issue of ... is easily picked up in fitness centers, schools, ...all burden of MRSA within hospitals, the report fo...
(Date:11/23/2009)...ervation Society says that western lowland gorilla...part of the "mother lode" of more than 125,000 gor...y threatened by growing humans activity in the reg...amp forests adjacent to the southwest border of La...med that high densities of the great apes still ex...
(Date:11/23/2009)...vides "incontrovertible evidence" that the volcani...about 73,000 years ago deforested much of central ...chers report. , The volcano ejected an estimated...leaving a crater (now the world,s largest volcanic...rs wide. Ash from the event has been found in Indi...
Breaking Biology News(10 mins):New study finds MRSA on the rise in hospital outpatients 2A year after discovery, Congo's 'mother lode' of gorillas remains vulnerable 2Supervolcano eruption -- in Sumatra -- deforested India 73,000 years ago 2Cardiac Patients Across Rural America Risk Losing Access to Nearby Care as Federal Agency Considers Cuts this Week 60042 1Cardiac Patients Across Rural America Risk Losing Access to Nearby Care as Federal Agency Considers Cuts this Week 60042 2Cardiac Patients Across Rural America Risk Losing Access to Nearby Care as Federal Agency Considers Cuts this Week 60042 3Wellcome Trust funds dengue fever research in Leuven 10516 1Wellcome Trust funds dengue fever research in Leuven 10516 2Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 1Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 2Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 3Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 4Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 5Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 6Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 7Positive Data from Arena Pharmaceuticals Pivotal BLOOM Trial Demonstrate that Lorcaserin Significantly Improved Markers of Cardiovascular Risk and Gly 60041 8
(Date:11/24/2009)...NTACRUZ,Calif.,Nov.24/PRNewswire/--Twomoreprestigi...,sleadingonlinejobboardandcareerssiteforlifescienc...rsityarenowmembersofthejobboard,joining28othermajo...d, www.biocareercenter.com ,isonlyforpost-graduate...ncecareersitesontheInternet,BioCareerCenteristheon...
(Date:11/24/2009)...YKJAVIK,Iceland,November24/PRNewswire-FirstCall/--...hatithasreceivednoticefrom,theNasdaqStockMarkettha...sofNovember30,2009andaForm25-NSEwillbefiledwiththe...CODE,scommonstock,fromlistingonNasdaq,unlessthecom...Panel.Thecompanyhasfiledsuchanappeal,which,willsta...
(Date:11/24/2009)... Health care employment grew by 2...nly one to show consistent growth during the U.S. ...s remain in trouble, and health systems are coming...l, instead of just administrators. , ...re employment continued growing in October despite...
(Date:11/24/2009)...ANGHAI,Nov.24/PRNewswire-Asia/--NODPharmaceuticals...hasallowedthepatentapplicationfor,itsnano-particle...sahighlyefficientapproachtoincorporatepeptidesor,p...eliveryofdrugs,otherwiseadministeredasinjections.N...tomanymacromoleculardrugssuchasinsulin,interferon,...
Breaking Biology Technology:Two Major Universities Join Nation's Leading Postgrad Bio Job Board 2deCODE Receives Delisting Notice From Nasdaq, Plans to Appeal 2deCODE Receives Delisting Notice From Nasdaq, Plans to Appeal 3The MedZilla Report for October 2009 - Health Care Employment Grows Again in October Even As Clinics, Specialty Centers Close 2The MedZilla Report for October 2009 - Health Care Employment Grows Again in October Even As Clinics, Specialty Centers Close 3The MedZilla Report for October 2009 - Health Care Employment Grows Again in October Even As Clinics, Specialty Centers Close 4
Other News:
...ARBOR, MI - The message that a common pain relieve...er certain conditions seems to have reached most p...ies in getting the word out to their patients and ...hysicians to assess how well they understand the p...
...rch into genetic susceptibility to Alzheimers dise...eptibility locus for Alzheimers disease in a prosp...omatic individuals (GS Zubenko, HB Hughes III, and...L JUNE 18 at 17:00 ET US), is addressed by religio...
...American Society for Microbiology's "Don't Get Cau...onored with two awards for excellence from the Pub...erican Society of Association Executives (ASAE).. ...d from PRSA at a ceremony in New York City June 14...
The Johns Hopkins Medicine Department of Radiology has been selected to take part in the first major study assessing the value of digital mammography versus standard mammography. The study, called th
Doctors aware of Tylenol-related liver risk - but is the public getting the message? 2Doctors aware of Tylenol-related liver risk - but is the public getting the message? 3Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 2Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 3Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 4Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 5Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 6Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 7Alzheimer's genetic susceptibility could bring fear and misunderstanding, religious scholars say 8ASM receives awards for PR excellence 2
...gy Limited have identified a way of switching off ...pment and growth of a tumour. Under the Wellcome T...archers hope to use their findings to develop a dr...g will be used to develop the drug to a point at w...
Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a b
...Society (ACS) News Service Weekly press package (P...reviewed journals and Chemical & Engineering News....0, 2007...ALL CONTENT IS FOR IMMEDIATE USE EXCEPT ...N. 15, 2007)...... PressPac Archive: http://www.ch...
...were not completely "modern" and continued to evol...00 years ago, according to new research published ...my of Sciences (PNAS)....An international team of ...doctoral fellow, and Erik Trinkaus, Ph.D., profess...
Novel approach to cancer drug given major boost 2Scientists find new genetic clue to cause of Alzheimer's disease 2ACS News Service Weekly PressPac -- January 10, 2007 2ACS News Service Weekly PressPac -- January 10, 2007 3ACS News Service Weekly PressPac -- January 10, 2007 4ACS News Service Weekly PressPac -- January 10, 2007 5ACS News Service Weekly PressPac -- January 10, 2007 6ACS News Service Weekly PressPac -- January 10, 2007 7ACS News Service Weekly PressPac -- January 10, 2007 8