The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Taking a SNP in the gene pool: Scientists harvest human gene differences

What makes one person's genes different from another's? Very often, any difference is tiny: a change in one DNA base pair out of hundreds that make up a gene. Yet scientists are eager to catalog these base pair variations, known as single nucleotide polymorphisms, or SNPs, in the hopes of understanding how differences in our genes lead to differences in us. In the November issue of Genome Research, Kavita Garg, Philip Green, and Deborah Nickerson (University of Washington) report a method to identify common human SNPs located in active genes.

SNPs also arise in the large portion of DNA that does not encode active genes. To sift "coding" SNPs from such non-coding variations, Garg and colleagues made use of so-called cDNA "libraries," which are collections of active genes from one or more individuals. After searching each of 50 different libraries for known genes, they compared sequences from each library base by base to find representative differences between the individuals' genes. This approach yielded 201 coding SNPs, a promising harvest that suggests gene libraries will be a plentiful future source of important human SNPs.


'"/>

Contact: Peggy Calicchia
calicchi@cshl.org
516-367-6834
Cold Spring Harbor Laboratory
14-Nov-1999


Page: 1

Related biology news :

1. Taking aim at bioterrorism: UH professor gets HHS funding to battle anthrax
2. Taking the show on the road - Leading researchers to conduct hands-on science symposium for 500 San Francisco area high school students
3. Taking the long view: examining factors which influence Northern Spotted Owls
4. Taking the pulse of giants: Detecting change and its consequences in western mountain ecosystems
5. Taking vitamin supplements is a common behavior in the U.S.
6. Taking The Animal Out Of Animal Testing
7. Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients
8. National Science Foundation Is Taking Small Business Into A New Phase Of Innovation
9. Digging In And Taking Cover
10. Taking The "Ouch" Out Of Needles: Arrays Of "Microneedles" Offer New Technique For Drug Delivery
11. Intake Of Acetaminophen Increases Risk Of Excessive Anticoagulation In Patients Taking Warfarin
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Taking SNP the gene pool Scientists harvest human gene differences

(Date:11/19/2008)... virtual crime, treating an ageing population, and...l be the focus of a 20 million ($30.4 million) inv...sical Sciences Research Council (EPSRC), Technolog...iological Sciences Research Council (BBSRC). , T...areas where world-class scientific breakthroughs h...
(Date:11/19/2008)...alth threat to city dwellers posed by Southern Cal...have been underestimated by officials. , Detaile...evious California wild fires indicates that the co...health than is generally realized, according to a ...ildfires in Southern California. , The paper, en...
(Date:11/19/2008)...? At the time of birth, mouse ovaries are essent...ch primordial follicles are forming. This key time... of oocytes and follicles and instigates evelopmen...orm, the result is oocyte demise, yet oocytes are ... factors key to follicular formation and oocyte su...
(Date:11/19/2008)...f marine invertebrates worms, sponges, jellyfish ...of no more than two cells: a photoreceptor cell an...ots, resemble the ,proto-eyes, suggested by Charle...lution. They cannot form images but allow the anim...s crucial for phototaxis the swimming towards lig...
Breaking Biology News(10 mins):£20 million to fight virtual crime and treat our ageing population 2£20 million to fight virtual crime and treat our ageing population 3Where there's wildfire smoke, there's toxicity 2December 2008 highlights from Biology of Reproduction 2Uncovering secrets of life in the ocean 2STERIS Isomedix Services Offers Gamma Engineering Run Program 26456 1STERIS Isomedix Services Offers Gamma Engineering Run Program 26456 2MultiVu Video Feed 3A Salvation Army Responding to Hurricane Ike With Food Water 26 Pastoral Care 26453 1MultiVu Video Feed 3A Salvation Army Responding to Hurricane Ike With Food Water 26 Pastoral Care 26453 2Unisys Selects Edifecs Healthcare Accelerator Suite 28TM 29 for MMIS System 26450 1Unisys Selects Edifecs Healthcare Accelerator Suite 28TM 29 for MMIS System 26450 2iMedica Announces Agreement with Misys 26447 1iMedica Announces Agreement with Misys 26447 2
Other News:
...geneticists from Cardiff School of Biosciences has...utan.......The population has declined up to one h...g with the arrival of colonial powers on the islan...e research is among the first to link species decl...
...re effective at knocking out community-acquired pn...tibiotic that has been the front-line CAP treatmen...oordinated at The University of Texas Health Scien...ading cause of death in the elderly, is diagnosed ...
..., zinc and other metals have determined that these...the needs of the global population forever, accord... National Academy of Sciences. ......According to ... the Earth's crust and extensive recycling program...
...f Conservation Biology examines the effects of hum... negative effects of tourism. Although first seein...n is rapid. The authors monitored the defensive h...esponse to stress (plasma corticosterone) of pengu...
Genetic evidence shows colonialists pushed orang-utans to brink of extinction 2Study: Newer antibiotic more effective at treating elders' pneumonia 2Yale study: Not enough metals in earth to meet global demand 2
...95 male and 3,413 female civil servants until the ...ntil 1999.......Deaths increased as the medically ...s) increased. Men and women who had more than five...death rate two to five times greater than those wi...
Delaying chemotherapy until symptoms develop for patients with asymptomatic advanced low-grade non-Hodgkin lymphoma is confirmed as an appropriate strategy authors of a UK study in this week's issue o
... THE LANCET shows that smokers in India are four t...is. Almost 200,000 people a year in India die from... deaths in India involve vascular disease, pulmona...the first major study of how smoking causes death ...
...obic exercise to prevent or control diabetes need ...re to realize its potential benefits, according to...issue of Diabetes, the Journal of the American Dia...cribed to help prevent or control Type 2 diabetes....
health news:Smoking causes half the tuberculosis deaths in Indian men 2health news:Mayo Clinic study finds people over 40 need frequent exercise to prevent or treat Type 2 diabetes 2
...premature use of stem cell therapy could put many ... appropriate safety systems are in place, warn exp...ryonic stem cells has been hailed as the next majo...disorders, such as diabetes and Parkinson's diseas...
A drug that is currently used to treat an enlarged prostate may improve the accuracy of prostate biopsies, a pilot study shows. ......The drug, dutasteride, suppresses blood flow in benign tissue of t
According to a new study, Canada lags behind other western countries in the level of financial support it gives to family caregivers. The international review was conducted as part of the Hidden Costs
...European Society for Medical Oncology (ESMO) is co...respected collection of Minimum Clinical Recommend...f documents that provide up-to-date information fr.....A new issue of ESMO's scientific journal, Annals...
health news:Premature use of stem cell therapy could put patients at risk 2health news:Canada lags behind in caregiver support 2health news:ESMO Minimum Clinical Recommendations 2