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Targeted Genetics presents advances in synthetic gene delivery technologies

ved in the majority of patients that initially had elevated levels and could be evaluated again after treatment. Based on these data, a 40 patient Phase II clinical trial in head and neck cancer was initiated in September of 1998. The trial uses the highest dose of tgDCC-E1A evaluated in patients with head and neck cancer in the Phase I study. Initial data from the Phase II study are expected to be presented at a scientific conference in the first half of 2000.

Targeted Genetics Corporation develops gene and cell therapy products for the treatment of certain acquired and inherited diseases. The Company has four lead product development programs targeting cystic fibrosis, hemophilia A, cancer, and infectious disease, as well as an extensive technology platform.


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Contact: Page Sargisson
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Noonan/Russo Communications
8-Dec-1999


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