Telomeres and Telomerase( Telomeres are the protective geneti...)

Telomeres and Telomerase

Telomeres are the protective genetic elements located at the ends of chromosomes and they are essential for correct chromosomal structure and function. During each round of replication, the enzyme telomerase is responsible for the maintenance of these chromosomal ends. This book:

draws together contributions from an interdisciplinary and international group of specialists concerned with research on all aspects of telomeres and telomerase
includes discussions of the genetic structure of telomeres, and the properties, roles and expression of telomerase
discusses the importance of telomeres and telomerase in cancer and ageing, as well as in DNA repair

CONTENTS

The telomere and telomerase: how do they interact?
E. BLACKBURN, A. BHATTACHARYYA, D. GILLEY, K. KIRK, A. KRAUSKOPF, M. MCEACHERN, J. PRESCOTT and T. WARE

Telomerase and the chromosome end replication problem
T. R. CECH and J. LINGNER

Characterization of the role of the EST genes in yeast telomerase function
T. HUGHES, D. MORRIS, N. WALCOTT, C. NUGENT, A. SALINGER and V. LUNDBLAD

Drosophila telomere elongation
H. BIESSMANN, M. F. WALTER and J. M. MASON

A protein-counting mechanism for telomere length regulation in yeast
D. SHORE, S. MARCAND and D. WOTTON

Chromatin and telomeres in ageing in yeast and mammals
B. KENNEDY, N. AUSTRIACO, D. LOMBARD, K. MILLS, T. SMEAL, R. MARCINIAK, S. MA, D. SINCLAIR and L. GUARENTE

The limited reproductive life span of normal human cells in culture
S. SHALL

Human ageing and telomeres
C. B. HARLEY

Telomerase and cancer
J. W. SHAY

Mouse models for telomerase function in cancer
M. A. BLASCO, H.-W LEE, R. DEPINHO and C. W. GREIDER

Telomerase repressor genes. Do they exist? How do we find them?<
'"/>

Contact: Dr Chris Langley
cklangley@novartisfound.org.uk
44 171 636 9456 x224
Novartis Foundation
22-Jan-1998

Page: 1 2
Related biology news :

1. Finding Reveals Broader Role Of Telomerase Enzyme, Suggesting New Target For Extending Life Span Of Cell
2. Research Team Discovers Key Gene For Telomerase Enzyme In Humans

Post Your Comments:

(Date:11/23/2009)...iated strain of the deadly superbug MRSAan infecti...ioticsposes a far greater health threat than previ...according to a study in the December issue of Eme... easily picked up in fitness centers, schools, and... burden of MRSA within hospitals, the report found...

(Date:11/23/2009)...ests that a common oral bacterium may exacerbate a...et al, "Unique Lipids from a Common Human Bacteriu... Enhancing Autoimmunity," appears in the December ... , Multiple sclerosis (MS), a disease where the ...ffects nearly 1 in 700 people in the United States...

(Date:11/23/2009)...University of Alabama at Birmingham (UAB) research...ng medical conditions (co-morbidity) do not explai...ericans compared to Caucasians who also have colon... Cancer , a journal of the American Cancer Society...co-morbidity are independent predictors of poor su...

Breaking Biology News(10 mins):New study finds MRSA on the rise in hospital outpatients 2 Factors from common human bacteria may trigger multiple sclerosis 2 Racial disparity in colon cancer survival not easily explained, UAB researchers say 2 Care Tech Laboratories Agrees to Stop Making Selling and Distributing Unapproved Antimicrobial Products 56497 1 Care Tech Laboratories Agrees to Stop Making Selling and Distributing Unapproved Antimicrobial Products 56497 2 Nepali Home Minister Commends Narconon International for Saving Lives 56495 1 Nepali Home Minister Commends Narconon International for Saving Lives 56495 2 The Dr Oz Show Names Core Team Oz 56493 1 The Dr Oz Show Names Core Team Oz 56493 2 The Dr Oz Show Names Core Team Oz 56493 3 The Dr Oz Show Names Core Team Oz 56493 4

[2] New study finds MRSA on the rise in hospital outpatients [0] Factors from common human bacteria may trigger multiple sclerosis [0] Racial disparity in colon cancer survival not easily explained, UAB researchers say

(Date:11/24/2009)...November24/PRNewswire-FirstCall/--deCODE,genetics,...fits,"firstday"motionsbytheU.S.BankruptcyCourtfort...lastweekfiledavoluntarypetitionfor,reliefunderChap...ptcyCourt. , TheordersissuedbytheBankruptcyCo...uringtheChapter11proceedings.Inparticular,the,comp...

(Date:11/24/2009)...v.24/PRNewswire-FirstCall/--NeurogesX,Inc.(Nasdaq:...ngandcommercializingnovelpainmanagementtherapies,a...xecutiveOfficer,isscheduledtopresentatthe21stAnnua...1-2,2009atTheNewYorkPalaceHotelinNewYork,NewYork. ...Officer,willbeavailabletorespondtoquestionsduringt...

(Date:11/24/2009)...ewswire/--BlueMarbleEnergyCorp.announcedtodaythatt...DA)wererecentlyawarded$2millionbyWashingtonState,s...te/publicpartnershiptoconstructthestate,sfirstspec..., "Thisinvestmentwillsignificantlyspeedthedevelop...lnCounty,"saidBlueMarbleEnergyCEOKellyOgilvie."Wea...

(Date:11/24/2009)...pointhasbeenmetforpatientswithadvanced-stage,orrec...PRNewswire-FirstCall/-AEternaZentarisInc.(NASDAQ: ...calcompanyfocusedonendocrinetherapyandoncology,tod...hitstargetedcytotoxicpeptideconjugate,AEZS-108(for...metrialcancer.Inapersonalizedhealthcareapproach,th...

Breaking Biology Technology:deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court 2 deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court 3 NeurogesX to Present at Piper Jaffray Health Care Conference 2 NeurogesX to Present at Piper Jaffray Health Care Conference 3 Blue Marble Energy, OPDA Awarded $2M by WA's Community Economic Revitalization Board 2 AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 2 AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 3 AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 4

[0] deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court [0] NeurogesX to Present at Piper Jaffray Health Care Conference [0] Blue Marble Energy, OPDA Awarded $2M by WA's Community Economic Revitalization Board [0] AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer

Other News:

...universities leave themselves open to lawsuits by ...g disorders, especially young women, according to ...l expert.. . Worse, most allow athletes to put th...s, lives at risk, says Barbara Bickford, assistant...

...g of the ozone layer, emissions...from the Mt. Pin...and...greenhouse gases into the atmosphere--may he...h's atmosphere has not warmed as quickly as the......per appearing in...the February 18 issue of the jo...

... Tests for Cancer Risk. . The Johns Hopkins scient...or colon cancer predisposition have now developed ...cy of such tests. They can now detect -- nearly 1...ated with certain hereditary diseases. A report o...

...t really answers, but more questions. .Elizabeth D..., does research on a lethal salamander virus. She... the world who are working together to find out wh...es as far and wide as North and Central America an...

Professor says college athletic departments must pay more attention to eating disorders 2 Professor says college athletic departments must pay more attention to eating disorders 3 Scientist find clues to different warming rates 2 Hopkins reports new technology to unmask hidden gene mutations 2 Hopkins reports new technology to unmask hidden gene mutations 3 ASU scientists probe salamander mysteries 2 ASU scientists probe salamander mysteries 3 ASU scientists probe salamander mysteries 4

Professor says college athletic departments must pay more attention to eating disorders Scientist find clues to different warming rates Hopkins reports new technology to unmask hidden gene mutations ASU scientists probe salamander mysteries

...stating blood-borne fungal infections that can be ...patients may be treated more successfully, thanks ...hers at the University of British Columbia in Vanc...Wasan has created a liquid preparation that incorp...

... our body every cell has a skeleton that provides ... fragile inner workings. The cytoskeleton is built...orks whose overall architecture and fine detail ca...icroscopy images. Researchers at the European Mole...

Drinking a specially-made cocoa beverage daily may have the potential to reverse impairments in the functioning of blood vessels, according to a first-of-its-kind study published in the Journal of Car

...AGO -- Photodynamic therapy (PDT) may be an effect...odontal diseases, and could provide a better optio... treating periodontal diseases, according to a new... of Periodontology.... Researchers at So Paulo Sta...

UBC researcher finds new way to treat devastating fungal infections 2 An architectural plan of the cell 2 New study suggests special cocoa may lead to sustained improvement in blood vessel function 2 New study suggests special cocoa may lead to sustained improvement in blood vessel function 3 New study suggests special cocoa may lead to sustained improvement in blood vessel function 4 Photodynamic therapy as alternative therapy for periodontal diseases may be beneficial 2

UBC researcher finds new way to treat devastating fungal infections An architectural plan of the cell New study suggests special cocoa may lead to sustained improvement in blood vessel function Photodynamic therapy as alternative therapy for periodontal diseases may be beneficial