HOME >> BIOLOGY >> NEWS
Test method provides biocompatibility 'barometer'

A new method for quantitatively measuring the compatibility of materials with living tissues has been developed by researchers at the National Institute of Standards and Technology (NIST). Described in a Dec. 11 presentation at the Tissue Engineering Society International's conference in Orlando, Fla., the technique should provide a more sensitive and reliable means to evaluate the biocompatibility of new materials for a wide range of applications from contact lenses to dental coatings to bone implants.

A paper outlining the new method has been accepted for publication in the Journal of Biomedical Materials Research.

The new method, which represents a novel application of existing bench-top scientific instruments, is a two-step process. The first step involves using a device called a polymerase chain reaction instrument to measure the levels of an organism's cytokines when exposed to a given material. Cytokines are signaling molecules released by white blood cells to protect the body from foreign materials. Higher levels of cytokine production generally indicate non-biocompatible materials have caused inflammation. The second step involves testing exposed cells for a specific protein in the cell membrane, the presence of which indicates cells are dying. This is a complementary test for more serious responses to materials because dying cells are often not capable of producing cytokines. The NIST tests were conducted on cultured mouse cells, which produce similar responses as whole tissues.

NIST post-doctoral researcher LeeAnn Bailey called the new method a "barometer" of biocompatibility.

Whereas current means to test biocompatibility produce a yes/no result that a material is minimally biocompatible or not, the new analysis can tell which materials are more biocompatible than others. Industry and researchers should be able to use this method to produce new materials for dentistry and other medical applications that are even more well
'"/>

Contact: Scott Nance
scott.nance@nist.gov
301-975-5226
National Institute of Standards and Technology (NIST)
19-Dec-2003


Page: 1 2

Related biology news :

1. OHSU researchers discover possible method for early detection, prevention of premature birth
2. Japanese researchers develop novel method of introducing transgenes into animals
3. New screening method turns up potential compound for treating anthrax
4. Radiologists provide safe delivery method for gene therapy
5. New method is first to mimic subtle genetic changes
6. New method for determining age of artifacts fills chronological gap for scientists
7. Proven method of bone analysis may clarify human origins
8. UVa researchers describe method of protecting chromosomes during cell division
9. Computer method identifies potentially active enzymes
10. Risk and food are on the same plate: World food safety experts offer new methods to assess risk
11. Purdue engineers develop quick, inexpensive method to prototype microchips

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2017)... YORK , April 4, 2017   EyeLock ... today announced that the United States Patent and Trademark ... patent broadly covers the linking of an iris image ... same transaction) and represents the company,s 45 th ... latest patent is very timely given the multi-modal biometric ...
(Date:3/29/2017)...  higi, the health IT company that operates the ... , today announced a Series B investment from ... The new investment and acquisition accelerates higi,s strategy to ... population health activities through the collection and workflow integration ... collects and secures data today on behalf of over ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), ... published by MarketsandMarkets, the market is expected to be worth USD 18.98 billion ... Continue Reading ... ...      (Logo: ...
Breaking Biology News(10 mins):
(Date:5/26/2017)... Ca (PRWEB) , ... May 25, 2017 , ... ... of Terumo BCT case studies, describing how process development and economic ... new results of T-cell expansion using a hollow-fiber bioreactor system, along with techniques ...
(Date:5/24/2017)... ... May 23, 2017 , ... Triumph ... modular buildings, announced the launch of the Mobile Big Room. This state-of-the-art ... help support on-site teamwork and collaboration. , The Mobile Big Room enables ...
(Date:5/23/2017)... Westminster, Colorado (PRWEB) , ... May 23, 2017 , ... ... amaranth as the most troublesome and difficult to control weed in 12 categories of ... found. , Almost 200 weed scientists across the U.S. and Canada participated in the ...
(Date:5/23/2017)... (PRWEB) , ... May 23, 2017 , ... Vortex ... of “Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology ” ... result of a collaboration with Dr. Dino Di Carlo and Dr. Matthew Rettig at ...
Breaking Biology Technology:
Cached News: