HOME >> BIOLOGY >> NEWS
Testosterone, stress may not suppress immune system after all

Testosterone has been blamed for everything from the muscular prose of Ernest Hemingway to Wall Street greed to the invention of ice hockey. But the biggest rap against the hormone comes from the biomedical world, which long has maintained a correlation between elevated testosterone levels and a suppressed immune system. After all, males across species die earlier than females and are more prone to stress and disease.

Now a biologist at Washington University in St. Louis is suggesting a completely different role for the hormone that made John Travolta and John Wayne famous. Stanton Braude, Ph.D., a lecturer in biology in Arts and Sciences, analyzed a number of studies that focused on the phenomenon whereby bright or showy male animals advertise their disease resistance. For instance, a male bird, during mating season, will display showy feathers to let females know that he is healthy -- resistant to parasites -- and would be a good mate. This evolutionary trick could be likened to Travolta gliding on the dance floor or the Duke strutting through a saloon to talk to the bar maid. These studies, however, revealed a paradox: testosterone, a long-assumed immunosuppressive, is also known to trigger the sexual display. How, Braude asked, could an immunosuppressive play such a vital role?

"The whole idea that testosterone and stress suppress the immune system makes absolutely no sense evolutionarily," says Braude. "Why would we have evolved to shut off immunity when that's so important to keep us healthy? I began to search for another mechanism for testosterone."

Braude came across a new body of research -- about a dozen studies in all over the past five years -- that questions the whole idea of immunosuppression and suggests that, instead of suppressing the immune system, testosterone and other steroids play a key role in what's called immunoredistribution.

"The redistribution hypothesis predicts that when you are under stress the total number o
'"/>

Contact: Tony Fitzpatrick
tony_fitzpatrick@aismail.wustl.edu@internet
314-935-5272
Washington University in St. Louis
4-Oct-1999


Page: 1 2 3 4

Related biology news :

1. UCSD team determines cellular stress within body is critical
2. Genetic basis for individual variations in the response to stress
3. Memory fails you after severe stress
4. Need sex? Its probably something about stress
5. Mix of chemicals plus stress damages brain, liver in animals and likely in humans
6. Researchers-again-pinpoint why stress kills
7. Social stress adversely affects digestive function in subordinate cichlid fish
8. Hebrew University, German and British researchers develop means to help stress sufferers
9. A little stress may be good for you
10. Estrogen promotes gender differences in brains response to stress
11. Study finds new mothers are resistant to stress

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Testosterone stress may not suppress immune system after all

(Date:10/15/2014)... Alt will be awarded the 44th Rosenstiel Award for ... his pioneering research exploring the mechanisms of genomic instability ... cells. Alt is the second alumnus to win the ... Prize in 2003. , Alt is the Charles A. ... Harvard Medical School and an investigator at the Howard ...
(Date:10/14/2014)... 2014)—It,s been millions of years since T. rex ... by Ohio University scientists is breathing life back into ... dinosaur snouts. The research has important implications for how ... to enhance the sense of smell and cool their ... Ohio University doctoral student Jason Bourke, lead author of ...
(Date:10/14/2014)... 2014 – High doses of fish oil supplements, rich in ... type of irregular heartbeat in which the heart can beat ... the AFFORD trial led by the Montreal Heart Institute were ... Cardiology on October 7th. , For the trial, 337 ... randomly assigned to 4 grams of fish oil a day ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3
(Date:10/20/2014)... 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") ... orders to $5.8 million and provides a good start to Q4.  ... North America and one in the Middle ... at record levels," said Peter Bruijns , President & CEO. ... of Q3 than they have been for any complete year since ...
(Date:10/20/2014)... OncLive® is pleased ... at Thomas Jefferson University has joined its Strategic ... Alliance Partnership program, the Sidney Kimmel Cancer Center ... awareness of the Center’s cutting-edge research programs, comprehensive ... and other health care professionals from the Sidney ...
(Date:10/19/2014)... OCTOBER 20-22, 2014: The 9th Annual ... take place at the Congress Center Basel, ... now available at http://www.abim.ch . ... from all over the globe will exchange ... products and developments on the world market. ...
(Date:10/19/2014)... 19, 2014 The Asia-Pacific Speech Analytics ... in Asia-Pacific with analysis and forecast of revenue. This ... 2014 to $208 million by 2019, at a Compound ... 2019. , Browse through the TOC of the Asia-Pacific ... the in-depth analysis provided. It also provides a glimpse ...
Breaking Biology Technology:Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
Cached News: