The biology of induced memory

"Imagine the possible benefit for people traumatized by haunting memories of terror or tragedy. The day may come when the cure is recalling the trauma, and then erasing it with a shot", wondered Dallas Morning News reporter Tom Siegfried (Aug. 28, 2000) commenting on Dr. Karim Nader's discovery that a fear memory induced in a rat and reactivated after 1 -12 days of storage in the outer part of the brain could be eradicated with a shot of anisomycin, a protein-synthesis inhibitor.

Two years after the publication of "Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval" in the August 14, 2000 issue of Nature, Dr. Nader and his colleague from New York University , neuroscientist Joseph E. Ledoux, published in the October 24, 2002, issue of Neuron, an article which shows that the same reconsolidation process goes on in another part of the brain which mediates conscious memories, the hippocampus.

"Whether we speak of rats or human beings, we store memories in analogous areas of the brain," say Dr. Nader, now a professor in the McGill Department of Psychology. " Our first findings were based on earlier work identifying the amygdala as a site at which neural changes that underlies auditory fear learning occur. It is a kind of learning that can happen unconsciously. We found evidence that contradicts entrenched psychological and neurobiological models of memory. Current theories posit that memories are processed by our brain initially as sensitive, labile short-term memories (stm) and then get stored as long-term memories (ltm). the transition from stm to ltm is mediated by the production of proteins. Once stored, the memory trace is posited to be "fixed" or "consolidated" in the brain. We found that stored fear experiences in the amygdala, when retrieved, return to a state that again requires protein synthesis in order to be restored or reconsolidated. Thus, if you reactivate the fear memory and block the produ

Contact: Karim Nader
McGill University

Page: 1 2 3

Related biology news :

1. Tips from the Journals of the American Society for Microbiology
2. NSF announces six FIBR awards to tackle some of biologys most challenging questions
3. Integrative biology of exercise APS Intersociety meeting October 6-9, 2004 in Austin
4. No longer just for biology, RNA can now be built into 3-D arrays
5. Tips from the journals of the American Society for Microbiology
6. Shedding new light on biology
7. Joslin Diabetes Center launches research section on developmental and stem cell biology
8. Report outlines vision and recommendations for microbiology in the 21st Century
9. Carnivore extinction risk determined more by biology than human population density, says study
10. Tips from the Journals of the American Society for Microbiology
11. Society for conservation biology conference

Post Your Comments:

(Date:8/7/2020)... (PRWEB) , ... August 06, 2020 , ... ... sciences industry, is pleased to announce that Eric Chen and Jessica Wong have ... of Product Management & Strategy, respectively. , Eric Chen heads development efforts for ...
(Date:7/31/2020)... FRANCISCO (PRWEB) , ... July 30, 2020 , ... ... maturing prescription digital therapeutics product portfolio with a near term focus on Type ... biotech and pharma commercialization experience across multiple therapeutic areas and classes. As Chief ...
(Date:7/10/2020)... ... July 09, 2020 , ... Today CJ BIO announced the first in ... on the “fifth taste” phenomenon that is revolutionizing ingredient mixes, nutritional content and flavor ... live on Monday, July 13, 2020 at11:00 AM (CDT) during SHIFT20, the virtual edition ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... SOMERSET, N.J (PRWEB) , ... July 29, 2020 ... ... editing company, and Catalent, the leading global provider of advanced delivery technologies, development, ... products, today announced that they have entered into a strategic partnership whereby Catalent ...
(Date:7/31/2020)... ... July 30, 2020 , ... Alucio™, ... announced the release of its signature product called Beacon - a content ... other field medical professionals. , Beacon helps MSLs streamline communication and ...
(Date:7/18/2020)... ... 16, 2020 , ... “We are thrilled to deliver this new technology to ... of its kind on the market and we were pleased that the IFT jury ... traditional cultured ingredients, creating a natural way to extend the shelf life and improve ...
(Date:7/10/2020)... LORTON, Va. (PRWEB) , ... July 08, 2020 ... ... laboratory testing services and products, announces a significant expansion of laboratory operations through ... robust collection for agencies implementing testing programs. , Bode-CARES provides ...
Breaking Biology Technology:
Cached News: